node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCN2 | YAP1 | ENSPANP00000018720 | ENSPANP00000036839 | Connective tissue growth factor (Predicted). | Yes associated protein 1. | 0.418 |
RUNX3 | TEAD1 | ENSPANP00000044766 | ENSPANP00000043207 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | TEA domain transcription factor 1. | 0.406 |
RUNX3 | TEAD2 | ENSPANP00000044766 | ENSPANP00000047109 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | TEA domain transcription factor 2. | 0.402 |
RUNX3 | TEAD3 | ENSPANP00000044766 | ENSPANP00000041657 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. | 0.402 |
RUNX3 | TEAD4 | ENSPANP00000044766 | ENSPANP00000008502 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. | 0.434 |
RUNX3 | WWTR1 | ENSPANP00000044766 | ENSPANP00000000586 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | WW domain containing transcription regulator 1. | 0.608 |
RUNX3 | YAP1 | ENSPANP00000044766 | ENSPANP00000036839 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | Yes associated protein 1. | 0.608 |
TEAD1 | RUNX3 | ENSPANP00000043207 | ENSPANP00000044766 | TEA domain transcription factor 1. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.406 |
TEAD1 | TEAD2 | ENSPANP00000043207 | ENSPANP00000047109 | TEA domain transcription factor 1. | TEA domain transcription factor 2. | 0.970 |
TEAD1 | TEAD3 | ENSPANP00000043207 | ENSPANP00000041657 | TEA domain transcription factor 1. | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. | 0.747 |
TEAD1 | TEAD4 | ENSPANP00000043207 | ENSPANP00000008502 | TEA domain transcription factor 1. | Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. | 0.921 |
TEAD1 | WWTR1 | ENSPANP00000043207 | ENSPANP00000000586 | TEA domain transcription factor 1. | WW domain containing transcription regulator 1. | 0.988 |
TEAD1 | YAP1 | ENSPANP00000043207 | ENSPANP00000036839 | TEA domain transcription factor 1. | Yes associated protein 1. | 0.992 |
TEAD2 | RUNX3 | ENSPANP00000047109 | ENSPANP00000044766 | TEA domain transcription factor 2. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.402 |
TEAD2 | TEAD1 | ENSPANP00000047109 | ENSPANP00000043207 | TEA domain transcription factor 2. | TEA domain transcription factor 1. | 0.970 |
TEAD2 | TEAD3 | ENSPANP00000047109 | ENSPANP00000041657 | TEA domain transcription factor 2. | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. | 0.745 |
TEAD2 | TEAD4 | ENSPANP00000047109 | ENSPANP00000008502 | TEA domain transcription factor 2. | Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. | 0.906 |
TEAD2 | WWTR1 | ENSPANP00000047109 | ENSPANP00000000586 | TEA domain transcription factor 2. | WW domain containing transcription regulator 1. | 0.998 |
TEAD2 | YAP1 | ENSPANP00000047109 | ENSPANP00000036839 | TEA domain transcription factor 2. | Yes associated protein 1. | 0.991 |
TEAD3 | RUNX3 | ENSPANP00000041657 | ENSPANP00000044766 | Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.402 |