STRINGSTRING
G6PC G6PC ENSPANP00000047250 ENSPANP00000047250 ENSPANP00000046741 ENSPANP00000046741 ENSPANP00000046574 ENSPANP00000046574 AKT2 AKT2 FOXO4 FOXO4 KLF4 KLF4 GCK GCK PCK1 PCK1 SMAD2 SMAD2 YWHAG YWHAG ENSPANP00000033894 ENSPANP00000033894 ENSPANP00000033198 ENSPANP00000033198 ATXN3 ATXN3 ENSPANP00000030575 ENSPANP00000030575 TXN TXN YWHAQ YWHAQ ENSPANP00000030356 ENSPANP00000030356 ENSPANP00000029718 ENSPANP00000029718 PCBP4 PCBP4 ENSPANP00000027020 ENSPANP00000027020 TRIM63 TRIM63 ENSPANP00000025126 ENSPANP00000025126 CDKN1B CDKN1B ENSPANP00000022606 ENSPANP00000022606 NFYB NFYB SIRT1 SIRT1 SREBF1 SREBF1 BCL6B BCL6B PPARGC1A PPARGC1A PINK1 PINK1 DDIT3 DDIT3 BCL2L11 BCL2L11 KAT2B KAT2B CCNG2 CCNG2 FOXG1 FOXG1 YWHAB YWHAB ABCA6 ABCA6 YWHAZ YWHAZ HDAC2 HDAC2 MSTN MSTN BCL6 BCL6 SMAD3 SMAD3 CREBBP CREBBP EP300 EP300 AKT1 AKT1 RBL2 RBL2 NFYA NFYA CDKN1A CDKN1A TXNIP TXNIP FOXO6 FOXO6 PLXNA4 PLXNA4 AGRP AGRP ENSPANP00000010220 ENSPANP00000010220 SIN3A SIN3A ENSPANP00000009516 ENSPANP00000009516 STK11 STK11 ENSPANP00000009040 ENSPANP00000009040 GADD45A GADD45A SFN SFN KLF2 KLF2 FOXO1 FOXO1 POMC POMC ENSPANP00000007424 ENSPANP00000007424 SMAD4 SMAD4 IGFBP1 IGFBP1 FASLG FASLG SIRT3 SIRT3 BTG1 BTG1 FOXO3 FOXO3 HDAC1 HDAC1 GDF11 GDF11 NFYC NFYC INS INS SOD2 SOD2 CAT CAT FBXO32 FBXO32 AKT3 AKT3 RETN RETN NR3C1 NR3C1 ENSPANP00000000656 ENSPANP00000000656
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
ENSPANP00000047250Thioredoxin domain-containing protein. (100 aa)
ENSPANP00000046741CBFD_NFYB_HMF domain-containing protein. (276 aa)
ENSPANP00000046574Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (452 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
FOXO4Forkhead box O4. (505 aa)
KLF4Kruppel like factor 4. (511 aa)
GCKPhosphotransferase. (480 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
SMAD2Mothers against decapentaplegic homolog. (472 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
ENSPANP00000033894annotation not available (101 aa)
ENSPANP00000033198Hist_deacetyl domain-containing protein. (225 aa)
ATXN3Ataxin 3. (366 aa)
ENSPANP0000003057514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (218 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
YWHAQTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (267 aa)
ENSPANP0000003035614_3_3 domain-containing protein; Belongs to the 14-3-3 family. (227 aa)
ENSPANP00000029718Thioredoxin; Belongs to the thioredoxin family. (101 aa)
PCBP4Poly(rC) binding protein 4. (411 aa)
ENSPANP00000027020Hist_deacetyl domain-containing protein. (267 aa)
TRIM63Tripartite motif containing 63. (383 aa)
ENSPANP0000002512614_3_3 domain-containing protein; Belongs to the 14-3-3 family. (209 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
ENSPANP0000002260614_3_3 domain-containing protein; Belongs to the 14-3-3 family. (217 aa)
NFYBNuclear transcription factor Y subunit beta. (208 aa)
SIRT1Sirtuin 1. (743 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1177 aa)
BCL6BBCL6B transcription repressor. (474 aa)
PPARGC1APPARG coactivator 1 alpha. (793 aa)
PINK1PTEN induced kinase 1. (581 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (344 aa)
FOXG1Forkhead box G1. (489 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
ABCA6ATP binding cassette subfamily A member 6. (1618 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (246 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (503 aa)
MSTNMyostatin. (375 aa)
BCL6BCL6 transcription repressor. (700 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
CREBBPCREB binding protein. (2442 aa)
EP300E1A binding protein p300. (2427 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
RBL2RB transcriptional corepressor like 2. (1140 aa)
NFYANuclear transcription factor Y subunit alpha. (347 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
TXNIPThioredoxin interacting protein. (391 aa)
FOXO6Forkhead box O6. (462 aa)
PLXNA4Plexin A4. (1950 aa)
AGRPAgouti related neuropeptide. (132 aa)
ENSPANP0000001022014_3_3 domain-containing protein; Belongs to the 14-3-3 family. (257 aa)
SIN3ASIN3 transcription regulator family member A. (1197 aa)
ENSPANP0000000951614_3_3 domain-containing protein; Belongs to the 14-3-3 family. (257 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa)
ENSPANP00000009040Thioredoxin; Belongs to the thioredoxin family. (105 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
KLF2Kruppel like factor 2. (356 aa)
FOXO1Forkhead box O1. (655 aa)
POMCProopiomelanocortin. (265 aa)
ENSPANP00000007424Anti_prolifrtn domain-containing protein. (162 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
IGFBP1Insulin like growth factor binding protein 1. (281 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (282 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (399 aa)
BTG1Uncharacterized protein. (171 aa)
FOXO3Forkhead box O3. (672 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (455 aa)
GDF11Growth differentiation factor 11. (406 aa)
NFYCNuclear transcription factor Y subunit gamma. (439 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (238 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
FBXO32F-box protein 32. (355 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
RETNResistin. (108 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (708 aa)
ENSPANP00000000656Thioredoxin; Belongs to the thioredoxin family. (101 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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