STRINGSTRING
MDM2 MDM2 TOP2A TOP2A EIF5B EIF5B WT1 WT1 EIF4G2 EIF4G2 BCL2 BCL2 SLC7A1 SLC7A1 CEBPA CEBPA ATF5 ATF5 ADH5 ADH5 GTF3A GTF3A HDLBP HDLBP SP3 SP3 AMD1 AMD1 BCKDK BCKDK EIF5 EIF5 DDX17 DDX17 HCK HCK MTR MTR UCP2 UCP2 BAG1 BAG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1549 aa)
EIF5BEukaryotic translation initiation factor 5B. (1226 aa)
WT1WT1 transcription factor. (510 aa)
EIF4G2Eukaryotic translation initiation factor 4 gamma 2. (925 aa)
BCL2BCL2 apoptosis regulator. (238 aa)
SLC7A1Solute carrier family 7 member 1. (629 aa)
CEBPACCAAT/enhancer-binding protein. (349 aa)
ATF5Activating transcription factor 5. (284 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
GTF3AGeneral transcription factor IIIA. (409 aa)
HDLBPHigh density lipoprotein binding protein. (1268 aa)
SP3Sp3 transcription factor. (780 aa)
AMD1S-adenosylmethionine decarboxylase proenzyme. (334 aa)
BCKDKProtein-serine/threonine kinase. (412 aa)
EIF5Eukaryotic translation initiation factor 5. (444 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (733 aa)
HCKTyrosine-protein kinase. (504 aa)
MTRMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1268 aa)
UCP2Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
BAG1BCL2 associated athanogene 1. (347 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.