STRINGSTRING
TNNT2 TNNT2 MYOCD MYOCD PDE1A PDE1A CACNB2 CACNB2 RHOA RHOA PDE1C PDE1C ENSPANP00000037492 ENSPANP00000037492 PTGS1 PTGS1 PDE1B PDE1B CNN1 CNN1 MYH11 MYH11 ENSPANP00000034073 ENSPANP00000034073 TPM1 TPM1 PDE4B PDE4B PDE4D PDE4D CACNA2D1 CACNA2D1 ROCK1 ROCK1 ALOX15 ALOX15 TRAF1 TRAF1 CPA3 CPA3 ACTG2 ACTG2 KCNK3 KCNK3 PDE5A PDE5A JAG1 JAG1 MYL9 MYL9 ACTC1 ACTC1 ABCC9 ABCC9 PTGIS PTGIS EDN1 EDN1 TNNI3 TNNI3 KCNA2 KCNA2 PTGS2 PTGS2 SLCO2A1 SLCO2A1 HPGD HPGD PTGER4 PTGER4 HAS2 HAS2 MYL2 MYL2 LOX LOX ENSPANP00000004977 ENSPANP00000004977 ATP1B1 ATP1B1 PDE3A PDE3A MYL6 MYL6 IFNG IFNG CNN3 CNN3 LOC101005011 LOC101005011 RHOB RHOB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNNT2Troponin T2, cardiac type. (302 aa)
MYOCDMyocardin. (984 aa)
PDE1APhosphodiesterase. (545 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
RHOARas homolog family member A. (193 aa)
PDE1CPhosphodiesterase. (768 aa)
ENSPANP00000037492Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (308 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (632 aa)
PDE1BPhosphodiesterase. (538 aa)
CNN1Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (310 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1985 aa)
ENSPANP00000034073Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (290 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (326 aa)
PDE4BPhosphodiesterase. (736 aa)
PDE4DPhosphodiesterase. (510 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1103 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
ALOX15Arachidonate 15-lipoxygenase. (662 aa)
TRAF1TNF receptor-associated factor. (416 aa)
CPA3Carboxypeptidase A3. (417 aa)
ACTG2Actin gamma 2, smooth muscle. (376 aa)
KCNK3Potassium channel subfamily K member. (389 aa)
PDE5APhosphodiesterase. (875 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1190 aa)
MYL9Myosin light chain 9. (172 aa)
ACTC1Actin alpha cardiac muscle 1. (372 aa)
ABCC9ATP binding cassette subfamily C member 9. (1549 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (493 aa)
EDN1Endothelin 1. (211 aa)
TNNI3Troponin I3, cardiac type. (211 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (356 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
SLCO2A1Solute carrier organic anion transporter family member. (643 aa)
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
HAS2Hyaluronan synthase 2. (552 aa)
MYL2Myosin light chain 2. (166 aa)
LOXLysyl oxidase. (417 aa)
ENSPANP00000004977Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (281 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
PDE3APhosphodiesterase. (1141 aa)
MYL6Uncharacterized protein. (218 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (165 aa)
CNN3Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (329 aa)
LOC101005011Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (309 aa)
RHOBRas homolog family member B. (196 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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