STRINGSTRING
HBB HBB TLR4 TLR4 CALR3 CALR3 HSP90B1 HSP90B1 SERPINH1 SERPINH1 BANP BANP TLR1 TLR1 CALR CALR USPL1 USPL1 CD180 CD180 DUSP8 DUSP8 SERPINC1 SERPINC1 FABP3 FABP3 MYL2 MYL2 FGB FGB TLR2 TLR2 ATF3 ATF3 GAPDH GAPDH GOT2 GOT2 LDHB LDHB SERPIND1 SERPIND1 CD40 CD40 FGG FGG HSPA5 HSPA5 GOT1 GOT1 ZFAND2A ZFAND2A CHORDC1 CHORDC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HBBHemoglobin subunit beta; Involved in oxygen transport from the lung to the various peripheral tissues. (147 aa)
TLR4Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] (836 aa)
CALR3Calreticulin. (384 aa)
HSP90B1Heat shock protein 90 beta family member 1. (815 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
BANPBTG3 associated nuclear protein. (528 aa)
TLR1Toll-like receptor. (786 aa)
CALRCalreticulin. (417 aa)
USPL1Ubiquitin specific peptidase like 1. (1093 aa)
CD180CD180 molecule. (661 aa)
DUSP8Dual specificity phosphatase 8. (505 aa)
SERPINC1Serpin family C member 1; Belongs to the serpin family. (428 aa)
FABP3Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
MYL2Myosin light chain 2. (166 aa)
FGBFibrinogen beta chain. (491 aa)
TLR2Toll-like receptor. (784 aa)
ATF3Activating transcription factor 3. (181 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
GOT2Aspartate aminotransferase. (430 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
SERPIND1Serpin family D member 1; Belongs to the serpin family. (499 aa)
CD40Uncharacterized protein. (262 aa)
FGGFibrinogen gamma chain. (437 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (592 aa)
GOT1Aspartate aminotransferase. (413 aa)
ZFAND2AAN1-type domain-containing protein. (204 aa)
CHORDC1CHORD domain-containing protein. (121 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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