STRINGSTRING
IL6 IL6 SIRT1 SIRT1 FST FST GDF11 GDF11 CD4 CD4 ICAM1 ICAM1 MSTN MSTN PECAM1 PECAM1 BDNF BDNF APOE APOE COMT COMT IGF1 IGF1 FSTL3 FSTL3 VCAM1 VCAM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL6Uncharacterized protein. (214 aa)
SIRT1Sirtuin 1. (743 aa)
FSTFollistatin. (344 aa)
GDF11Growth differentiation factor 11. (406 aa)
CD4CD4 molecule. (458 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
MSTNMyostatin. (375 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (738 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (312 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
COMTCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (271 aa)
IGF1Insulin like growth factor 1. (208 aa)
FSTL3Follistatin like 3. (265 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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