STRINGSTRING
PRKCZ PRKCZ DGKI DGKI CDC42BPG CDC42BPG DGKD DGKD PRKCB PRKCB RAF1 RAF1 UNC13B UNC13B PRKCQ PRKCQ PRKD1 PRKD1 UNC13A UNC13A DGKG DGKG KSR2 KSR2 PRKD2 PRKD2 VAV3 VAV3 AKAP13 AKAP13 CDC42BPA CDC42BPA PRKCE PRKCE RASGRP1 RASGRP1 CIT CIT VAV2 VAV2 LOC101010448 LOC101010448 PRKCG PRKCG ROCK1 ROCK1 PLEKHM1 PLEKHM1 STAC2 STAC2 DGKE DGKE KSR1 KSR1 BRAF BRAF RACGAP1 RACGAP1 PRKCH PRKCH PRKCA PRKCA PDZD8 PDZD8 PRKD3 PRKD3 CHN2 CHN2 MYO9A MYO9A UNC13C UNC13C CDC42BPB CDC42BPB ROCK2 ROCK2 PRKCD PRKCD STAC STAC DGKQ DGKQ ENSPANP00000009247 ENSPANP00000009247 RASGRP3 RASGRP3 ARHGEF28 ARHGEF28 MYO9B MYO9B STAC3 STAC3 ARHGAP29 ARHGAP29 TNS2 TNS2 PRKCI PRKCI RASGRP2 RASGRP2 GMIP GMIP ARHGAP45 ARHGAP45 CHN1 CHN1 DGKA DGKA DGKB DGKB KMT2C KMT2C RASSF1 RASSF1 ARHGEF2 ARHGEF2 RASSF5 RASSF5 PLEKHM3 PLEKHM3 DEF8 DEF8 RASGRP4 RASGRP4 ARAF ARAF VAV1 VAV1 DGKH DGKH DGKZ DGKZ DGKK DGKK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (591 aa)
DGKIDiacylglycerol kinase. (1079 aa)
CDC42BPGUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1559 aa)
DGKDDiacylglycerol kinase. (1216 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
RAF1Uncharacterized protein. (668 aa)
UNC13BUncharacterized protein. (4337 aa)
PRKCQProtein kinase C. (753 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa)
UNC13AUnc-13 homolog A. (1581 aa)
DGKGDiacylglycerol kinase. (791 aa)
KSR2Kinase suppressor of ras 2. (950 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (888 aa)
VAV3Vav guanine nucleotide exchange factor 3. (872 aa)
AKAP13A-kinase anchoring protein 13. (2875 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1716 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
RASGRP1RAS guanyl releasing protein 1. (842 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
LOC101010448Phorbol-ester/DAG-type domain-containing protein. (142 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (701 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
PLEKHM1Pleckstrin homology and RUN domain containing M1. (986 aa)
STAC2SH3 and cysteine rich domain 2. (411 aa)
DGKEDiacylglycerol kinase. (558 aa)
KSR1Kinase suppressor of ras 1. (932 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
RACGAP1Rac GTPase activating protein 1. (632 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PDZD8PDZ domain containing 8. (1154 aa)
PRKD3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (890 aa)
CHN2Chimaerin; GTPase-activating protein for p21-rac. (468 aa)
MYO9AMyosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2548 aa)
UNC13CUnc-13 homolog C. (2216 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1711 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
STACSH3 and cysteine rich domain. (402 aa)
DGKQDiacylglycerol kinase. (945 aa)
ENSPANP00000009247Uncharacterized protein. (583 aa)
RASGRP3RAS guanyl releasing protein 3. (734 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28. (1729 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2157 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
ARHGAP29Rho GTPase activating protein 29. (1266 aa)
TNS2Tensin 2. (1419 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
RASGRP2Uncharacterized protein. (621 aa)
GMIPGEM interacting protein. (974 aa)
ARHGAP45Rho GTPase activating protein 45. (1159 aa)
CHN1Chimaerin; GTPase-activating protein for p21-rac. (459 aa)
DGKADiacylglycerol kinase. (735 aa)
DGKBDiacylglycerol kinase. (803 aa)
KMT2CLysine methyltransferase 2C. (4887 aa)
RASSF1Ras association domain family member 1. (344 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1031 aa)
RASSF5Ras association domain family member 5. (418 aa)
PLEKHM3Pleckstrin homology domain containing M3. (761 aa)
DEF8Differentially expressed in FDCP 8 homolog. (512 aa)
RASGRP4RAS guanyl releasing protein 4. (673 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
DGKHDiacylglycerol kinase. (1220 aa)
DGKZDiacylglycerol kinase. (1116 aa)
DGKKDiacylglycerol kinase. (1281 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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