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MFSD11 MFSD11 GSS GSS AHCY AHCY MTR MTR MAT2A MAT2A KYAT1 KYAT1 PSAT1 PSAT1 MAT1A MAT1A GOT1 GOT1 LTO1 LTO1 ENSPANP00000021852 ENSPANP00000021852 ENSPANP00000022020 ENSPANP00000022020 IL4I1 IL4I1 ENSPANP00000023058 ENSPANP00000023058 ENSPANP00000023548 ENSPANP00000023548 ENSPANP00000026052 ENSPANP00000026052 ENSPANP00000026478 ENSPANP00000026478 BCAT1 BCAT1 DNMT3A DNMT3A BCAT2 BCAT2 SRM SRM ENSPANP00000028881 ENSPANP00000028881 ENSPANP00000029921 ENSPANP00000029921 CTH CTH ENSPANP00000030778 ENSPANP00000030778 ENSPANP00000033589 ENSPANP00000033589 ENSPANP00000033977 ENSPANP00000033977 ENSPANP00000035148 ENSPANP00000035148 HSD17B14 HSD17B14 MPST MPST TST TST GCLC GCLC GOT2 GOT2 CBS CBS ADI1 ADI1 SCUBE3 SCUBE3 APIP APIP AMD1 AMD1 SDS SDS TFB2M TFB2M RNF138 RNF138 KYAT3 KYAT3 MDH2 MDH2 MAT2B MAT2B ENOPH1 ENOPH1 LDHC LDHC AGXT2 AGXT2 MDH1B MDH1B SMS SMS AHCYL1 AHCYL1 LDHAL6A LDHAL6A CDO1 CDO1 ACCS ACCS ACCSL ACCSL TRDMT1 TRDMT1 SCUBE2 SCUBE2 URB2 URB2 LOC103877626 LOC103877626 SDSL SDSL GCLM GCLM DIMT1 DIMT1 BHMT BHMT SRFBP1 SRFBP1 DNMT1 DNMT1 PHGDH PHGDH MRI1 MRI1 TFB1M TFB1M TSTD1 TSTD1 LDHB LDHB ENSPANP00000047529 ENSPANP00000047529 SCUBE1 SCUBE1 ENSPANP00000046298 ENSPANP00000046298 ENSPANP00000046292 ENSPANP00000046292 MTAP MTAP ENSPANP00000045671 ENSPANP00000045671 ENSPANP00000045522 ENSPANP00000045522 AHCYL2 AHCYL2 VBP1 VBP1 FTCDNL1 FTCDNL1 MDH1 MDH1 TSTD3 TSTD3 DNMT3B DNMT3B ENSPANP00000039351 ENSPANP00000039351 GOT1L1 GOT1L1 ENSPANP00000038537 ENSPANP00000038537 ENSPANP00000038393 ENSPANP00000038393 TAT TAT ENSPANP00000015767 ENSPANP00000015767
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MFSD11Major facilitator superfamily domain containing 11. (449 aa)
GSSGlutathione synthetase. (474 aa)
AHCYAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (431 aa)
MTRMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1268 aa)
MAT2AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa)
KYAT1Aminotran_1_2 domain-containing protein. (515 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
MAT1AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
GOT1Aspartate aminotransferase. (413 aa)
LTO1LTO1 maturation factor of ABCE1. (225 aa)
ENSPANP00000021852Uncharacterized protein; Belongs to the LDH/MDH superfamily. (342 aa)
ENSPANP00000022020Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (312 aa)
IL4I1Amine oxidase. (589 aa)
ENSPANP00000023058Ldh_1_N domain-containing protein. (87 aa)
ENSPANP00000023548L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (272 aa)
ENSPANP00000026052Aminotran_5 domain-containing protein. (172 aa)
ENSPANP00000026478Uncharacterized protein; Belongs to the LDH/MDH superfamily. (337 aa)
BCAT1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (873 aa)
BCAT2Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (434 aa)
SRMSpermidine synthase; Belongs to the spermidine/spermine synthase family. (324 aa)
ENSPANP00000028881rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (351 aa)
ENSPANP00000029921PNP_UDP_1 domain-containing protein. (192 aa)
CTHCystathionine gamma-lyase. (430 aa)
ENSPANP00000030778PABS domain-containing protein. (235 aa)
ENSPANP00000033589Uncharacterized protein. (278 aa)
ENSPANP00000033977Uncharacterized protein. (305 aa)
ENSPANP00000035148Uncharacterized protein; Belongs to the LDH/MDH superfamily. (396 aa)
HSD17B14Hydroxysteroid 17-beta dehydrogenase 14. (267 aa)
MPSTSulfurtransferase. (317 aa)
TSTSulfurtransferase. (297 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
GOT2Aspartate aminotransferase. (430 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (565 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (1009 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa)
AMD1S-adenosylmethionine decarboxylase proenzyme. (334 aa)
SDSSerine dehydratase. (328 aa)
TFB2MrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (430 aa)
RNF138Ring finger protein 138. (245 aa)
KYAT3Kynurenine aminotransferase 3. (453 aa)
MDH2Malate dehydrogenase. (338 aa)
MAT2BMethionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (336 aa)
ENOPH1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (242 aa)
LDHCL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
AGXT2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (513 aa)
MDH1BMalate dehydrogenase 1B. (544 aa)
SMSPABS domain-containing protein. (366 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
LDHAL6AL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
CDO1Cysteine dioxygenase. (200 aa)
ACCS1-aminocyclopropane-1-carboxylate synthase homolog (inactive). (501 aa)
ACCSL1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like. (568 aa)
TRDMT1tRNA aspartic acid methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (391 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (1025 aa)
URB2URB2 ribosome biogenesis homolog. (1483 aa)
LOC103877626L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (360 aa)
SDSLSerine dehydratase like. (329 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (274 aa)
DIMT1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (313 aa)
BHMTBetaine--homocysteine S-methyltransferase. (470 aa)
SRFBP1Serum response factor binding protein 1. (428 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1617 aa)
PHGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (559 aa)
MRI1Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (369 aa)
TFB1MrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (345 aa)
TSTD1Thiosulfate sulfurtransferase like domain containing 1. (122 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
ENSPANP00000047529Uncharacterized protein. (82 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (1024 aa)
ENSPANP00000046298Aminotran_5 domain-containing protein. (376 aa)
ENSPANP00000046292Aminotran_5 domain-containing protein. (341 aa)
MTAPS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (333 aa)
ENSPANP00000045671Uncharacterized protein. (321 aa)
ENSPANP00000045522S-adenosylmethionine decarboxylase proenzyme. (334 aa)
AHCYL2Adenosylhomocysteinase like 2; Belongs to the adenosylhomocysteinase family. (610 aa)
VBP1VHL binding protein 1. (239 aa)
FTCDNL1Formiminotransferase cyclodeaminase N-terminal like. (147 aa)
MDH1Malate dehydrogenase. (352 aa)
TSTD3Thiosulfate sulfurtransferase like domain containing 3. (81 aa)
DNMT3BDNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (853 aa)
ENSPANP00000039351L-lactate dehydrogenase. (239 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (401 aa)
ENSPANP00000038537L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (317 aa)
ENSPANP00000038393PABS domain-containing protein. (301 aa)
TATTyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (454 aa)
ENSPANP00000015767L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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