STRINGSTRING
LOC103887915 LOC103887915 CSDE1 CSDE1 CCND1 CCND1 BAD BAD ADCY2 ADCY2 PRKACB PRKACB HRAS HRAS SHC2 SHC2 PIK3R1 PIK3R1 E2F2 E2F2 ADCY3 ADCY3 BCL2 BCL2 ENSPANP00000001773 ENSPANP00000001773 PPP1R14B PPP1R14B DLL3 DLL3 PIK3R3 PIK3R3 AKT3 AKT3 CDKN1B CDKN1B ARAF ARAF EGFR EGFR NOTCH2 NOTCH2 PTRHD1 PTRHD1 PIK3CA PIK3CA DLL1 DLL1 ADCY8 ADCY8 HBEGF HBEGF GPER1 GPER1 ADCY1 ADCY1 PIK3R2 PIK3R2 CARM1 CARM1 ENSPANP00000007612 ENSPANP00000007612 CDK4 CDK4 RPS6KB2 RPS6KB2 ENSPANP00000009247 ENSPANP00000009247 SP1 SP1 NOTCH3 NOTCH3 MAPK9 MAPK9 NRAS NRAS CCDC170 CCDC170 GPSM3 GPSM3 NOTCH4 NOTCH4 MAPK3 MAPK3 MAPK14 MAPK14 CDKN1A CDKN1A ADCY7 ADCY7 MMP2 MMP2 AKT1 AKT1 JAG2 JAG2 LOC101014319 LOC101014319 BIK BIK MAPK12 MAPK12 MAPK11 MAPK11 ADCY9 ADCY9 CEP152 CEP152 SHC4 SHC4 GNAS GNAS PIK3CD PIK3CD ESR1 ESR1 NOTCH1 NOTCH1 MTOR MTOR MAPK13 MAPK13 RAF1 RAF1 DLL4 DLL4 ADCY5 ADCY5 EYS EYS MAP2K2 MAP2K2 ADCY6 ADCY6 MAPK10 MAPK10 IGF1 IGF1 ERBB2 ERBB2 IGF1R IGF1R BAX BAX SHC1 SHC1 PIK3CB PIK3CB MAPK8 MAPK8 TP53 TP53 E2F3 E2F3 SRC SRC CDKN2C CDKN2C NCOA3 NCOA3 RPS6KB1 RPS6KB1 MAPK1 MAPK1 ENSPANP00000024626 ENSPANP00000024626 ENSPANP00000024582 ENSPANP00000024582 LOC101014919 LOC101014919 PRKACA PRKACA KRAS KRAS AKT2 AKT2 PTK2 PTK2 FOS FOS GRB2 GRB2 E2F1 E2F1 SOS2 SOS2 JAG1 JAG1 ESR2 ESR2 SOS1 SOS1 MMP9 MMP9 ADCY4 ADCY4 ERAS ERAS RB1 RB1 MDM2 MDM2 ABCB11 ABCB11 BRAF BRAF SHC3 SHC3 NCOR1 NCOR1 MED1 MED1 MAP2K1 MAP2K1 CDKN2B CDKN2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103887915Uncharacterized protein. (245 aa)
CSDE1Cold shock domain containing E1. (844 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
BADBCL2 associated agonist of cell death. (168 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (338 aa)
HRASUncharacterized protein. (189 aa)
SHC2Uncharacterized protein. (567 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
E2F2E2F transcription factor 2. (438 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
BCL2BCL2 apoptosis regulator. (238 aa)
ENSPANP00000001773Uncharacterized protein. (189 aa)
PPP1R14BUncharacterized protein. (207 aa)
DLL3Delta like canonical Notch ligand 3. (618 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
NOTCH2Notch receptor 2. (2603 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
PIK3R2Uncharacterized protein. (721 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (608 aa)
ENSPANP00000007612Uncharacterized protein. (190 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
ENSPANP00000009247Uncharacterized protein. (583 aa)
SP1Sp1 transcription factor. (803 aa)
NOTCH3Notch receptor 3. (2315 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CCDC170Coiled-coil domain containing 170. (715 aa)
GPSM3G protein signaling modulator 3. (160 aa)
NOTCH4Notch receptor 4. (2000 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1213 aa)
LOC101014319Uncharacterized protein; Belongs to the cytochrome P450 family. (497 aa)
BIKBCL2 interacting killer. (160 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
CEP152Centrosomal protein 152. (1706 aa)
SHC4SHC adaptor protein 4. (630 aa)
GNASGNAS complex locus. (1037 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
NOTCH1Notch receptor 1. (2541 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
MAPK13Mitogen-activated protein kinase. (386 aa)
RAF1Uncharacterized protein. (668 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (713 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
EYSEyes shut homolog. (3164 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (385 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
MAPK10Mitogen-activated protein kinase. (467 aa)
IGF1Insulin like growth factor 1. (208 aa)
ERBB2Receptor protein-tyrosine kinase. (1399 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
SHC1SHC adaptor protein 1. (601 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
E2F3E2F transcription factor 3. (460 aa)
SRCTyrosine-protein kinase. (644 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
NCOA3Nuclear receptor coactivator. (1418 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ENSPANP00000024626Uncharacterized protein. (82 aa)
ENSPANP00000024582Uncharacterized protein. (147 aa)
LOC101014919Uncharacterized protein; Belongs to the cytochrome P450 family. (487 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
E2F1E2F transcription factor 1. (423 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1190 aa)
ESR2Uncharacterized protein. (530 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ERASES cell expressed Ras. (233 aa)
RB1RB transcriptional corepressor 1. (889 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa)
ABCB11ATP binding cassette subfamily B member 11. (1321 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
SHC3SHC adaptor protein 3. (598 aa)
NCOR1Nuclear receptor corepressor 1. (2442 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1548 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
CDKN2BUncharacterized protein. (173 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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