STRINGSTRING
ENSPANP00000047680 ENSPANP00000047680 ENSPANP00000047619 ENSPANP00000047619 ENSPANP00000047241 ENSPANP00000047241 ABCC3 ABCC3 RELA RELA ENSPANP00000043657 ENSPANP00000043657 ABCC1 ABCC1 IKBKB IKBKB ENSPANP00000034052 ENSPANP00000034052 SLC19A1 SLC19A1 IZUMO1R IZUMO1R ENSPANP00000026128 ENSPANP00000026128 IL6 IL6 CHUK CHUK ABCC2 ABCC2 SLC46A1 SLC46A1 SHMT1 SHMT1 ENSPANP00000019725 ENSPANP00000019725 ALOX12 ALOX12 FPGS FPGS ATIC ATIC ABCC5 ABCC5 IL1B IL1B TNF TNF GART GART NFKB1 NFKB1 DHFR DHFR TYMS TYMS GGH GGH MTHFR MTHFR LOC101021316 LOC101021316 ENSPANP00000005727 ENSPANP00000005727 ABCC4 ABCC4 FOLR3 FOLR3 SHMT2 SHMT2 ABCG2 ABCG2 FOLR1 FOLR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPANP00000047680annotation not available (132 aa)
ENSPANP00000047619DHFR domain-containing protein. (134 aa)
ENSPANP00000047241SHMT domain-containing protein. (426 aa)
ABCC3ATP binding cassette subfamily C member 3. (1527 aa)
RELARELA proto-oncogene, NF-kB subunit. (476 aa)
ENSPANP00000043657MGS domain-containing protein. (565 aa)
ABCC1ATP binding cassette subfamily C member 1. (1531 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (776 aa)
ENSPANP00000034052DHFR domain-containing protein. (132 aa)
SLC19A1Solute carrier family 19 member 1. (555 aa)
IZUMO1RIZUMO1 receptor, JUNO. (250 aa)
ENSPANP00000026128DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (175 aa)
IL6Uncharacterized protein. (214 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
ABCC2ATP binding cassette subfamily C member 2. (1545 aa)
SLC46A1Solute carrier family 46 member 1. (459 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa)
ENSPANP00000019725DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (170 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (663 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (587 aa)
ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (592 aa)
ABCC5ATP binding cassette subfamily C member 5. (1424 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
GARTTrifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1010 aa)
NFKB1Nuclear factor kappa B subunit 1. (977 aa)
DHFRDHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (161 aa)
TYMSThymidylate synthetase. (313 aa)
GGHFolate gamma-glutamyl hydrolase. (311 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (693 aa)
LOC101021316DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
ENSPANP00000005727DHFR domain-containing protein. (155 aa)
ABCC4ATP binding cassette subfamily C member 4. (1325 aa)
FOLR3Folate receptor gamma. (245 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
ABCG2ABC transporter domain-containing protein. (655 aa)
FOLR1Folate receptor alpha. (257 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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