STRINGSTRING
RAC2 RAC2 NGF NGF ENSPANP00000047688 ENSPANP00000047688 KRAS KRAS AKT2 AKT2 DRD2 DRD2 RAP1GAP RAP1GAP FGF17 FGF17 PRKCB PRKCB SIPA1L2 SIPA1L2 PVALEF PVALEF EFNA4 EFNA4 MAPK13 MAPK13 RAF1 RAF1 CTNND1 CTNND1 PFN1 PFN1 ADCY5 ADCY5 ENAH ENAH ENSPANP00000041348 ENSPANP00000041348 EFNA2 EFNA2 TLN1 TLN1 GRIN1 GRIN1 NGFR NGFR PGF PGF RHOA RHOA MAGI2 MAGI2 SKAP1 SKAP1 PRKD1 PRKD1 MAP2K2 MAP2K2 ENSPANP00000038985 ENSPANP00000038985 TIAM1 TIAM1 ADCY6 ADCY6 CDC42 CDC42 IGF1 IGF1 FLT4 FLT4 IGF1R IGF1R RAPGEF1 RAPGEF1 AFDN AFDN EVL EVL ITGB3 ITGB3 PLCB2 PLCB2 ACTG1 ACTG1 CALML6 CALML6 PRKD2 PRKD2 PIK3CB PIK3CB ENSPANP00000033457 ENSPANP00000033457 LOC100998766 LOC100998766 VAV3 VAV3 ITGB1 ITGB1 ENSPANP00000032942 ENSPANP00000032942 PLCB4 PLCB4 THBS1 THBS1 RAPGEF2 RAPGEF2 MET MET LPAR1 LPAR1 ENSPANP00000030371 ENSPANP00000030371 RAP1GAP2 RAP1GAP2 SRC SRC DOCK4 DOCK4 PARD3 PARD3 RALGDS RALGDS FYB1 FYB1 ADAM15 ADAM15 CALM2 CALM2 ENSPANP00000026453 ENSPANP00000026453 F2RL3 F2RL3 FGFR3 FGFR3 MAPK1 MAPK1 FGF9 FGF9 FGFR2 FGFR2 RAC3 RAC3 VAV2 VAV2 BCAR1 BCAR1 LOC103887915 LOC103887915 ITGAL ITGAL MAP2K1 MAP2K1 ENSPANP00000022011 ENSPANP00000022011 ENSPANP00000021931 ENSPANP00000021931 PRKCG PRKCG ENSPANP00000021298 ENSPANP00000021298 RGL4 RGL4 FGF8 FGF8 ITGA2B ITGA2B PLCE1 PLCE1 PDGFA PDGFA APBB1IP APBB1IP MAP2K3 MAP2K3 ADORA2B ADORA2B CRK CRK GNAQ GNAQ TEK TEK BRAF BRAF KIT KIT KRIT1 KRIT1 RAPGEF4 RAPGEF4 CSF1 CSF1 FGF2 FGF2 ERAS ERAS PFN2 PFN2 FGF23 FGF23 ANGPT2 ANGPT2 FGF3 FGF3 PLCG1 PLCG1 ADCY4 ADCY4 ENSPANP00000017591 ENSPANP00000017591 FGF19 FGF19 GNAI3 GNAI3 GRIN2B GRIN2B PARD6G PARD6G LOC100997719 LOC100997719 ADORA2A ADORA2A SIPA1L1 SIPA1L1 PLCB1 PLCB1 ENSPANP00000017007 ENSPANP00000017007 ANGPT4 ANGPT4 ID1 ID1 RALB RALB MAP2K6 MAP2K6 PRKCA PRKCA CRKL CRKL PRKD3 PRKD3 FGF18 FGF18 CALM1 CALM1 FGF20 FGF20 RALA RALA PDGFC PDGFC RPS6KL1 RPS6KL1 FGF22 FGF22 PIK3CD PIK3CD FGF6 FGF6 KDR KDR PARD6B PARD6B GNAS GNAS CALML4 CALML4 TLN2 TLN2 FGF7 FGF7 GALK2 GALK2 ENSPANP00000013909 ENSPANP00000013909 GRIN2A GRIN2A ADCY9 ADCY9 MAPK11 MAPK11 MAPK12 MAPK12 PDGFB PDGFB AKT1 AKT1 VEGFA VEGFA GNAO1 GNAO1 ITGB2 ITGB2 ADCY7 ADCY7 ITGAM ITGAM MAPK14 MAPK14 MAPK3 MAPK3 LAT LAT ENSPANP00000012445 ENSPANP00000012445 CALM3 CALM3 MAGI1 MAGI1 GPR55 GPR55 ENSPANP00000011336 ENSPANP00000011336 ACTL7B ACTL7B ENSPANP00000011252 ENSPANP00000011252 NRAS NRAS VEGFB VEGFB CSF1R CSF1R ACTL7A ACTL7A ACTB ACTB LPAR2 LPAR2 VASP VASP ACTRT2 ACTRT2 FGF5 FGF5 ENSPANP00000009247 ENSPANP00000009247 EFNA1 EFNA1 VEGFC VEGFC EGF EGF LCP2 LCP2 RASGRP3 RASGRP3 MAGI3 MAGI3 INSR INSR CALML3 CALML3 FGF1 FGF1 FARP2 FARP2 TRAC TRAC PLCB3 PLCB3 FGFR4 FGFR4 PDGFRB PDGFRB PRKCI PRKCI RASGRP2 RASGRP2 LOC100997587 LOC100997587 PIK3R2 PIK3R2 RAPGEF5 RAPGEF5 PDGFRA PDGFRA MRAS MRAS LPAR3 LPAR3 PARD6A PARD6A PFN4 PFN4 ADCY1 ADCY1 FLT1 FLT1 VEGFD VEGFD RAC1 RAC1 ANGPT1 ANGPT1 ADCY8 ADCY8 GNAI1 GNAI1 PRKCZ PRKCZ PDGFD PDGFD RGS12 RGS12 RAP1B RAP1B CTNNB1 CTNNB1 PIK3CA PIK3CA PTRHD1 PTRHD1 RRAS RRAS EPHA2 EPHA2 F2R F2R EGFR EGFR SIPA1L3 SIPA1L3 RAPGEF6 RAPGEF6 FGF21 FGF21 GNAI2 GNAI2 EFNA5 EFNA5 EFNA3 EFNA3 RGS14 RGS14 KITLG KITLG INS INS FGF16 FGF16 FGFR1 FGFR1 ACTL8 ACTL8 VAV1 VAV1 AKT3 AKT3 LOC101024285 LOC101024285 HGF HGF PIK3R3 PIK3R3 ENSPANP00000001773 ENSPANP00000001773 ADCY3 ADCY3 PIK3R1 PIK3R1 CDH1 CDH1 HRAS HRAS ADCY2 ADCY2 RHOC RHOC FGF10 FGF10 RAPGEF3 RAPGEF3 FGF4 FGF4 ACTRT1 ACTRT1 SIPA1 SIPA1 ARAP3 ARAP3 P2RY1 P2RY1 LPAR4 LPAR4 LPAR5 LPAR5 CSDE1 CSDE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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RAC2Rac family small GTPase 2. (192 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (123 aa)
ENSPANP00000047688Uncharacterized protein. (212 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
RAP1GAPRAP1 GTPase activating protein. (750 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
SIPA1L2Signal induced proliferation associated 1 like 2. (1700 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
EFNA4Ephrin A4; Belongs to the ephrin family. (206 aa)
MAPK13Mitogen-activated protein kinase. (386 aa)
RAF1Uncharacterized protein. (668 aa)
CTNND1Catenin delta 1. (971 aa)
PFN1Profilin; Belongs to the profilin family. (167 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
ENAHENAH actin regulator. (789 aa)
ENSPANP00000041348Uncharacterized protein. (182 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (213 aa)
TLN1Talin 1. (2558 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (960 aa)
NGFRNerve growth factor receptor. (429 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (184 aa)
RHOARas homolog family member A. (193 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1456 aa)
SKAP1Src kinase associated phosphoprotein 1. (359 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (385 aa)
ENSPANP00000038985Uncharacterized protein; Belongs to the actin family. (362 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1577 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
CDC42Cell division cycle 42. (191 aa)
IGF1Insulin like growth factor 1. (208 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1362 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1095 aa)
AFDNAfadin, adherens junction formation factor. (1826 aa)
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (422 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1170 aa)
ACTG1Actin gamma 1. (377 aa)
CALML6Calmodulin like 6. (181 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (888 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
ENSPANP00000033457Uncharacterized protein; Belongs to the calmodulin family. (99 aa)
LOC100998766Ras-GEF domain-containing protein. (591 aa)
VAV3Vav guanine nucleotide exchange factor 3. (872 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ENSPANP00000032942Uncharacterized protein. (182 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
THBS1Thrombospondin 1. (1175 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1701 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1404 aa)
LPAR1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ENSPANP00000030371Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
RAP1GAP2RAP1 GTPase activating protein 2. (771 aa)
SRCTyrosine-protein kinase. (644 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1997 aa)
PARD3Par-3 family cell polarity regulator. (1353 aa)
RALGDSUncharacterized protein. (915 aa)
FYB1FYN binding protein 1. (841 aa)
ADAM15ADAM metallopeptidase domain 15. (863 aa)
CALM2Calmodulin 2. (149 aa)
ENSPANP00000026453Uncharacterized protein. (128 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
FGFR3Fibroblast growth factor receptor. (775 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
RAC3Rac family small GTPase 3. (192 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
LOC103887915Uncharacterized protein. (245 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1204 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ENSPANP00000022011Uncharacterized protein. (153 aa)
ENSPANP00000021931Uncharacterized protein. (175 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (701 aa)
ENSPANP00000021298Ras-GEF domain-containing protein. (553 aa)
RGL4Ral guanine nucleotide dissociation stimulator like 4. (540 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
PLCE1Phosphoinositide phospholipase C. (2317 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (662 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (394 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
GNAQG protein subunit alpha q. (384 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
KRIT1Uncharacterized protein. (736 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1011 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (555 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
ERASES cell expressed Ras. (233 aa)
PFN2Profilin; Belongs to the profilin family. (188 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
ANGPT2Angiopoietin 2. (496 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ENSPANP00000017591Ras-GEF domain-containing protein. (579 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
GNAI3G protein subunit alpha i3. (354 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
PARD6GPar-6 family cell polarity regulator gamma. (376 aa)
LOC100997719Ras-GEF domain-containing protein. (593 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
SIPA1L1Signal induced proliferation associated 1 like 1. (1804 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1122 aa)
ENSPANP00000017007Ras-GEF domain-containing protein. (530 aa)
ANGPT4Angiopoietin 4. (503 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (163 aa)
RALBRAS like proto-oncogene B. (206 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
PRKD3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (890 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
CALM1Calmodulin 1. (149 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
RALARAS like proto-oncogene A. (206 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
RPS6KL1Ribosomal protein S6 kinase like 1. (549 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1315 aa)
PARD6BPar-6 family cell polarity regulator beta. (372 aa)
GNASGNAS complex locus. (1037 aa)
CALML4Calmodulin like 4. (194 aa)
TLN2Talin 2. (2545 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
GALK2Galactokinase 2. (458 aa)
ENSPANP00000013909Profilin; Belongs to the profilin family. (179 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (945 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (412 aa)
GNAO1G protein subunit alpha o1. (354 aa)
ITGB2Integrin beta. (919 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
LATLinker for activation of T cells. (270 aa)
ENSPANP00000012445Uncharacterized protein; Belongs to the actin family. (380 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
MAGI1Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1460 aa)
GPR55G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (319 aa)
ENSPANP00000011336Uncharacterized protein; Belongs to the actin family. (347 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
ENSPANP00000011252G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (378 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (975 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
ACTBActin beta. (379 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (377 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
ENSPANP00000009247Uncharacterized protein. (583 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1161 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
RASGRP3RAS guanyl releasing protein 3. (734 aa)
MAGI3Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1482 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1032 aa)
TRACT cell receptor alpha constant. (110 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
RASGRP2Uncharacterized protein. (621 aa)
LOC100997587Ras-GEF domain-containing protein. (590 aa)
PIK3R2Uncharacterized protein. (721 aa)
RAPGEF5Rap guanine nucleotide exchange factor 5. (730 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (353 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
PFN4Profilin; Belongs to the profilin family. (109 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1325 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
RAC1Rac family small GTPase 1. (211 aa)
ANGPT1Angiopoietin 1. (498 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
GNAI1G protein subunit alpha i1. (422 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (591 aa)
PDGFDPlatelet derived growth factor D. (303 aa)
RGS12Regulator of G protein signaling 12. (1447 aa)
RAP1BUncharacterized protein. (184 aa)
CTNNB1Catenin beta 1. (781 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
RRASRAS related. (218 aa)
EPHA2EPH receptor A2. (976 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
SIPA1L3Signal induced proliferation associated 1 like 3. (1777 aa)
RAPGEF6Uncharacterized protein. (1609 aa)
FGF21Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family. (174 aa)
GNAI2G protein subunit alpha i2. (355 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
EFNA3Ephrin A3; Belongs to the ephrin family. (238 aa)
RGS14Regulator of G protein signaling 14. (572 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGFR1Fibroblast growth factor receptor. (853 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC101024285Uncharacterized protein. (191 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (788 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
ENSPANP00000001773Uncharacterized protein. (189 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)
HRASUncharacterized protein. (189 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
RHOCRas homolog family member C. (193 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (925 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
SIPA1Signal-induced proliferation-associated 1. (1024 aa)
ARAP3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3. (1546 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
LPAR4Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (370 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa)
CSDE1Cold shock domain containing E1. (844 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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