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| | CDC7 | Protein kinase domain-containing protein. (574 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (860 aa) |
| | E2F2 | E2F transcription factor 2. (438 aa) |
| | E2F5 | E2F transcription factor 5. (346 aa) |
| | ANAPC5 | Anaphase promoting complex subunit 5. (755 aa) |
| | TFDP2 | Transcription factor. (446 aa) |
| | WEE1 | Wee1-like protein kinase. (646 aa) |
| | CCNB3 | Cyclin B3; Belongs to the cyclin family. (1363 aa) |
| | SKP1 | Uncharacterized protein; Belongs to the SKP1 family. (165 aa) |
| | CHEK1 | Checkpoint kinase 1. (480 aa) |
| | TMEM82 | Transmembrane protein 82. (343 aa) |
| | ENSPANP00000003354 | Protein kinase domain-containing protein. (555 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (455 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (575 aa) |
| | CDC20 | Cell division cycle 20. (499 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (904 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | ORC3 | Origin recognition complex subunit 3. (690 aa) |
| | MYNN | Myoneurin. (662 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1944 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | ZBTB17 | Zinc finger and BTB domain containing 17. (800 aa) |
| | ZBTB47 | Zinc finger and BTB domain containing 47. (748 aa) |
| | LOC101001699 | S-phase kinase-associated protein 1. (163 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | CDC23 | Cell division cycle 23. (597 aa) |
| | CDKN1C | Cyclin dependent kinase inhibitor 1C. (325 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | WEE2 | Wee1-like protein kinase. (568 aa) |
| | FBXW12 | F-box and WD repeat domain containing 12. (463 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | SFN | Stratifin; Belongs to the 14-3-3 family. (248 aa) |
| | GADD45A | Growth arrest and DNA damage inducible alpha. (165 aa) |
| | CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1198 aa) |
| | ENSPANP00000009516 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (257 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | ENSPANP00000010220 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (257 aa) |
| | FAM126B | Family with sequence similarity 126 member B. (530 aa) |
| | CCNB1 | Cyclin B1; Belongs to the cyclin family. (433 aa) |
| | CDC20B | Cell division cycle 20B. (519 aa) |
| | ENSPANP00000010444 | Transcription factor. (392 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | MAD2L1 | MAD2 mitotic arrest deficient-like 1 (Predicted). (205 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | CDC25A | Cell division cycle 25A. (524 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2630 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (603 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | CCND3 | Cyclin D3 (Predicted); Belongs to the cyclin family. (292 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1140 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (853 aa) |
| | E2F4 | E2F transcription factor 4. (417 aa) |
| | YWHAH | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide (Predicted); Belongs to the 14-3-3 family. (246 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | EP300 | E1A binding protein p300. (2427 aa) |
| | SMC1B | Structural maintenance of chromosomes protein. (1235 aa) |
| | CREBBP | CREB binding protein. (2442 aa) |
| | CCNB2 | Cyclin B2; Belongs to the cyclin family. (398 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | RAD21 | RAD21 cohesin complex component. (631 aa) |
| | CDC25C | Cell division cycle 25C. (458 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (503 aa) |
| | YWHAZ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (246 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4094 aa) |
| | CHEK2 | Checkpoint kinase 2. (589 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (1108 aa) |
| | MAD1L1 | Mitotic arrest deficient 1 like 1. (756 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | BUB1B | Uncharacterized protein. (1046 aa) |
| | ANAPC11 | Anaphase promoting complex subunit 11. (180 aa) |
| | BUB3 | WD_REPEATS_REGION domain-containing protein. (328 aa) |
| | E2F1 | E2F transcription factor 1. (423 aa) |
| | RAD21L1 | RAD21 cohesin complex component like 1. (556 aa) |
| | AP5S1 | Adaptor related protein complex 5 subunit sigma 1. (200 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | TTK | TTK protein kinase. (857 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa) |
| | ESPL1 | Extra spindle pole bodies like 1, separase. (2095 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (224 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | RB1 | RB transcriptional corepressor 1. (889 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa) |
| | ANAPC4 | Anaphase promoting complex subunit 4. (981 aa) |
| | DBF4 | DBF4 zinc finger. (675 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1217 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | ZNF652 | Zinc finger protein 652. (537 aa) |
| | CDK1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa) |
| | CDC27 | Cell division cycle 27. (830 aa) |
| | CDC25B | Cell division cycle 25B. (570 aa) |
| | PKMYT1 | Protein kinase, membrane associated tyrosine/threonine 1. (568 aa) |
| | CDKN2B | Uncharacterized protein. (173 aa) |
| | STAG1 | Stromal antigen 1. (1258 aa) |
| | ENSPANP00000022606 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (217 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (176 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | ENSPANP00000023509 | Protein kinase domain-containing protein. (322 aa) |
| | ENSPANP00000025126 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (209 aa) |
| | ENSPANP00000025308 | DOC domain-containing protein. (110 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa) |
| | ENSPANP00000027020 | Hist_deacetyl domain-containing protein. (267 aa) |
| | ENSPANP00000027322 | Uncharacterized protein. (66 aa) |
| | CDC14A | Cell division cycle 14A. (624 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (325 aa) |
| | ENSPANP00000028654 | Uncharacterized protein. (297 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) |
| | CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (329 aa) |
| | ENSPANP00000030356 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (227 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (304 aa) |
| | YWHAQ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (267 aa) |
| | ENSPANP00000030575 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (218 aa) |
| | ZBTB46 | Zinc finger and BTB domain containing 46. (589 aa) |
| | PTTG1 | PTTG1 regulator of sister chromatid separation, securin. (202 aa) |
| | ORC2 | Origin recognition complex subunit 2. (577 aa) |
| | CDC26 | Cell division cycle 26. (85 aa) |
| | ENSPANP00000032423 | Protein kinase domain-containing protein. (297 aa) |
| | LOC101001092 | Uncharacterized protein. (182 aa) |
| | CDC14C | Cell division cycle 14C. (553 aa) |
| | E2F3 | E2F transcription factor 3. (460 aa) |
| | ENSPANP00000033198 | Hist_deacetyl domain-containing protein. (225 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) |
| | CDC16 | Cell division cycle 16. (620 aa) |
| | CDK20 | Cyclin dependent kinase 20. (359 aa) |
| | ABL1 | Tyrosine-protein kinase. (1112 aa) |
| | YWHAG | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa) |
| | ZBTB10 | Zinc finger and BTB domain containing 10. (827 aa) |
| | ENSPANP00000035397 | Rad21_Rec8 domain-containing protein. (524 aa) |
| | CDC45 | Cell division cycle 45. (598 aa) |
| | ENSPANP00000035959 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (196 aa) |
| | ENSPANP00000037027 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (244 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (472 aa) |
| | ANAPC13 | Anaphase promoting complex subunit 13. (74 aa) |
| | CDC14B | Cell division cycle 14B. (498 aa) |
| | STAG2 | Stromal antigen 2. (1241 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa) |
| | BUB1 | BUB1 mitotic checkpoint serine/threonine kinase. (1096 aa) |
| | CNTD2 | Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (304 aa) |
| | ENSPANP00000041917 | Zf-rbx1 domain-containing protein. (93 aa) |
| | MAD2L1-2 | HORMA domain-containing protein. (206 aa) |
| | SKP2 | S-phase kinase associated protein 2. (424 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (524 aa) |
| | ENSPANP00000046574 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (452 aa) |
| | RBX1 | RING-type domain-containing protein. (108 aa) |
