STRINGSTRING
MAP2K2 MAP2K2 PPP1R12C PPP1R12C PPP1R12A PPP1R12A KCNMB1 KCNMB1 LOC101005611 LOC101005611 ARHGEF12 ARHGEF12 RHOC RHOC ADCY2 ADCY2 LYVE1 LYVE1 PRKACB PRKACB ADCY3 ADCY3 MYL6 MYL6 PLA2G1B PLA2G1B EDN2 EDN2 LOC101013375 LOC101013375 ESYT3 ESYT3 PLA2G2A PLA2G2A PLA2G4A PLA2G4A ARAF ARAF CALCRL CALCRL PTRHD1 PTRHD1 KCNMB4 KCNMB4 GUCY1A1 GUCY1A1 NPPB NPPB ADCY8 ADCY8 PLA2G2E PLA2G2E KCNU1 KCNU1 CACNA1S CACNA1S EDNRA EDNRA ADCY1 ADCY1 ETV3L ETV3L ARHGEF11 ARHGEF11 ADRA1B ADRA1B MRVI1 MRVI1 AGT AGT PPP1R14A PPP1R14A PLCB3 PLCB3 ERF ERF CALML3 CALML3 GNA11 GNA11 LOC101015173 LOC101015173 ENSPANP00000009247 ENSPANP00000009247 GUCY1A2 GUCY1A2 PLA2G2C PLA2G2C ERFL ERFL PPP1CA PPP1CA ITPR2 ITPR2 NPPA NPPA ENSPANP00000010678 ENSPANP00000010678 AVPR1A AVPR1A KCNMB3 KCNMB3 PLA2G2F PLA2G2F PLA2G5 PLA2G5 MYL6B MYL6B PRKCD PRKCD CALM3 CALM3 MYLK MYLK CALCA CALCA ITPR3 ITPR3 MAPK3 MAPK3 MYLK3 MYLK3 ADCY7 ADCY7 ROCK2 ROCK2 PLA2G3 PLA2G3 MYH9 MYH9 PLA2G6 PLA2G6 MYLK4 MYLK4 EDN1 EDN1 ADCY9 ADCY9 PLA2G10 PLA2G10 CALML4 CALML4 EDN3 EDN3 GNAS GNAS CALD1 CALD1 ETV3 ETV3 CALM1 CALM1 AVPR1B AVPR1B JMJD7 JMJD7 PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F GNA13 GNA13 PRKCA PRKCA MYL9 MYL9 AVP AVP ADRA1D ADRA1D PLCB1 PLCB1 PRKCH PRKCH ADORA2A ADORA2A LOC101014452 LOC101014452 ADCY4 ADCY4 NPPC NPPC ACTG2 ACTG2 BRAF BRAF NPR2 NPR2 GNAQ GNAQ MYH10 MYH10 ADORA2B ADORA2B PROCA1 PROCA1 PLA2G12B PLA2G12B PRKG1 PRKG1 EFCAB13 EFCAB13 EFCAB3 EFCAB3 ROCK1 ROCK1 PRKCG PRKCG ADM ADM MAP2K1 MAP2K1 LOC103887915 LOC103887915 GNA12 GNA12 CACNA1C CACNA1C PLA2G4C PLA2G4C PRKCE PRKCE ENSPANP00000025762 ENSPANP00000025762 RAMP2 RAMP2 MAPK1 MAPK1 AGTR1 AGTR1 CACNA1F CACNA1F CALM2 CALM2 ENSPANP00000029897 ENSPANP00000029897 ENSPANP00000030371 ENSPANP00000030371 CALCB CALCB ADRA1A ADRA1A PLA2G12A PLA2G12A PLCB4 PLCB4 KCNMA1 KCNMA1 KCNMB2 KCNMB2 ARHGEF1 ARHGEF1 ENSPANP00000033457 ENSPANP00000033457 ENSPANP00000033712 ENSPANP00000033712 PTGIR PTGIR CALML6 CALML6 MYH11 MYH11 PLCB2 PLCB2 PPP1CB PPP1CB GUCY1B1 GUCY1B1 MYH14 MYH14 PLA2G4B PLA2G4B PPP1R12B PPP1R12B ADCY6 ADCY6 RAMP3 RAMP3 NPR1 NPR1 PRKCQ PRKCQ RHOA RHOA CACNA1D CACNA1D ADCY5 ADCY5 PLA2G2D PLA2G2D RAF1 RAF1 PVALEF PVALEF PRKCB PRKCB ESYT2 ESYT2 ESYT1 ESYT1 ITPR1 ITPR1 MYLK2 MYLK2 PPP1CC PPP1CC PRKACA PRKACA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (385 aa)
PPP1R12CProtein phosphatase 1 regulatory subunit. (783 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1029 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
LOC101005611Uncharacterized protein. (189 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1517 aa)
RHOCRas homolog family member C. (193 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
LYVE1Lymphatic vessel endothelial hyaluronan receptor 1. (321 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (338 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
MYL6Uncharacterized protein. (218 aa)
PLA2G1BPhospholipase A(2). (148 aa)
EDN2Endothelin 2. (178 aa)
LOC101013375Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
ESYT3Extended synaptotagmin 3. (861 aa)
PLA2G2APhospholipase A(2). (144 aa)
PLA2G4APhospholipase A2. (749 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (472 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (688 aa)
NPPBNatriuretic peptide B. (132 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
PLA2G2EPhospholipase A(2). (142 aa)
KCNU1Potassium calcium-activated channel subfamily U member 1. (1152 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
ETV3LETS variant 3 like. (361 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1550 aa)
ADRA1BAdrenoceptor alpha 1B. (518 aa)
MRVI1Murine retrovirus integration site 1 homolog. (913 aa)
AGTAngiotensinogen; Belongs to the serpin family. (490 aa)
PPP1R14AProtein phosphatase 1 regulatory inhibitor subunit 14A. (147 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
ERFETS2 repressor factor. (548 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
GNA11G protein subunit alpha 11. (359 aa)
LOC101015173Uncharacterized protein. (430 aa)
ENSPANP00000009247Uncharacterized protein. (583 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (727 aa)
PLA2G2CPhospholipase A(2). (151 aa)
ERFLETS repressor factor like. (354 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
NPPANatriuretic peptide A. (153 aa)
ENSPANP00000010678Uncharacterized protein. (152 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (301 aa)
PLA2G2FPhospholipase A(2). (210 aa)
PLA2G5Phospholipase A(2). (138 aa)
MYL6BMyosin light chain 6B. (210 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
MYLKMyosin light chain kinase. (1875 aa)
CALCACalcitonin related polypeptide alpha. (140 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2680 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
MYLK3Myosin light chain kinase 3. (819 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1962 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (443 aa)
EDN1Endothelin 1. (211 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PLA2G10Phospholipase A(2). (165 aa)
CALML4Calmodulin like 4. (194 aa)
EDN3Endothelin 3. (230 aa)
GNASGNAS complex locus. (1037 aa)
CALD1Caldesmon 1. (793 aa)
ETV3ETS variant 3. (511 aa)
CALM1Calmodulin 1. (149 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (424 aa)
JMJD7Jumonji domain containing 7. (316 aa)
PLA2G4EPhospholipase A2. (869 aa)
PLA2G4DPhospholipase A2. (817 aa)
PLA2G4FPhospholipase A2. (849 aa)
GNA13G protein subunit alpha 13. (377 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
MYL9Myosin light chain 9. (172 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (148 aa)
ADRA1DAdrenoceptor alpha 1D. (570 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1122 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
LOC101014452Uncharacterized protein. (455 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
NPPCNatriuretic peptide C. (126 aa)
ACTG2Actin gamma 2, smooth muscle. (376 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
NPR2Guanylate cyclase. (1047 aa)
GNAQG protein subunit alpha q. (384 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
PROCA1Protein interacting with cyclin A1. (363 aa)
PLA2G12BPhospholipase A2 group XIIB. (195 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
EFCAB13EF-hand calcium binding domain 13. (973 aa)
EFCAB3EF-hand calcium binding domain 3. (488 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (701 aa)
ADMAdrenomedullin. (184 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC103887915Uncharacterized protein. (245 aa)
GNA12G protein subunit alpha 12. (381 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
PLA2G4CPhospholipase A2 group IVC. (558 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
ENSPANP00000025762Uncharacterized protein. (157 aa)
RAMP2Receptor activity modifying protein 2. (180 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1961 aa)
CALM2Calmodulin 2. (149 aa)
ENSPANP00000029897Uncharacterized protein. (115 aa)
ENSPANP00000030371Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
CALCBCalcitonin related polypeptide beta. (138 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
PLA2G12APhospholipase A2 group XIIA. (189 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1285 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (998 aa)
ENSPANP00000033457Uncharacterized protein; Belongs to the calmodulin family. (99 aa)
ENSPANP00000033712Uncharacterized protein. (74 aa)
PTGIRProstaglandin I2 receptor. (386 aa)
CALML6Calmodulin like 6. (181 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1985 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1170 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (328 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (642 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
PLA2G4BPhospholipase A2. (781 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (1045 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
RAMP3Receptor activity modifying protein 3. (151 aa)
NPR1Guanylate cyclase. (1074 aa)
PRKCQProtein kinase C. (753 aa)
RHOARas homolog family member A. (193 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
PLA2G2DPhospholipase A(2). (145 aa)
RAF1Uncharacterized protein. (668 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ESYT2Extended synaptotagmin 2. (938 aa)
ESYT1Extended synaptotagmin 1. (1141 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2723 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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