STRINGSTRING
PRF1 PRF1 ENSPANP00000019978 ENSPANP00000019978 KLRC1 KLRC1 SYK SYK SHC3 SHC3 BRAF BRAF ENSPANP00000018668 ENSPANP00000018668 IFNAR1 IFNAR1 ERAS ERAS PLCG1 PLCG1 GZMB GZMB ULBP3 ULBP3 PRKCA PRKCA IFNGR2 IFNGR2 SOS2 SOS2 BID BID LOC103883952 LOC103883952 ENSPANP00000017234 ENSPANP00000017234 LOC101022300 LOC101022300 ENSPANP00000017241 ENSPANP00000017241 RAET1E RAET1E FYN FYN LOC101013367 LOC101013367 SOS1 SOS1 LOC101023471 LOC101023471 PPP3CC PPP3CC PTPN11 PTPN11 TNFRSF10B TNFRSF10B PAK1 PAK1 PIK3R2 PIK3R2 HCST HCST NCR1 NCR1 IFNAR2 IFNAR2 NFATC1 NFATC1 LCP2 LCP2 CSDE1 CSDE1 KIR3DL3 KIR3DL3 HRAS HRAS SHC2 SHC2 PIK3R1 PIK3R1 PTK2B PTK2B ENSPANP00000001773 ENSPANP00000001773 IFNG IFNG KLRG1 KLRG1 PIK3R3 PIK3R3 VAV1 VAV1 NCR3 NCR3 SH2D1B SH2D1B CD244 CD244 CSF2 CSF2 TNFRSF10A TNFRSF10A ARAF ARAF TNFSF10 TNFSF10 PIK3CA PIK3CA ICAM1 ICAM1 KLRD1 KLRD1 CASP3 CASP3 FASLG FASLG RAC1 RAC1 ENSPANP00000009247 ENSPANP00000009247 IFNB1 IFNB1 PLCG2 PLCG2 ENSPANP00000010471 ENSPANP00000010471 KLRK1 KLRK1 SH2D1A SH2D1A TNF TNF NRAS NRAS LOC101011325 LOC101011325 ENSPANP00000011803 ENSPANP00000011803 ZAP70 ZAP70 LAT LAT MAPK3 MAPK3 NCR2 NCR2 ITGB2 ITGB2 RAC2 RAC2 CEP152 CEP152 SHC4 SHC4 SRMS SRMS PTK6 PTK6 KIR2DL4 KIR2DL4 ENSPANP00000014914 ENSPANP00000014914 PIK3CD PIK3CD IFNGR1 IFNGR1 GRB2 GRB2 ICAM2 ICAM2 LOC101017701 LOC101017701 KRAS KRAS LOC101018055 LOC101018055 LOC101002478 LOC101002478 ENSPANP00000045653 ENSPANP00000045653 TYROBP TYROBP PRKCB PRKCB LOC101016823 LOC101016823 ENSPANP00000043887 ENSPANP00000043887 LCK LCK RAF1 RAF1 LOC101006295 LOC101006295 CD247 CD247 TREML4 TREML4 PPP3CA PPP3CA LOC101002123 LOC101002123 ENSPANP00000041355 ENSPANP00000041355 ENSPANP00000041348 ENSPANP00000041348 IFNA6 IFNA6 NFATC2 NFATC2 MAP2K2 MAP2K2 ENSPANP00000037764 ENSPANP00000037764 ENSPANP00000036759 ENSPANP00000036759 SHC1 SHC1 LOC101019008 LOC101019008 ENSPANP00000033846 ENSPANP00000033846 PIK3CB PIK3CB VAV3 VAV3 FCGR3A FCGR3A LOC101002253 LOC101002253 PTPN6 PTPN6 ENSPANP00000030750 ENSPANP00000030750 ENSPANP00000030153 ENSPANP00000030153 ENSPANP00000028630 ENSPANP00000028630 CD48 CD48 FCER1G FCER1G ENSPANP00000026706 ENSPANP00000026706 MAPK1 MAPK1 LOC101015094 LOC101015094 ENSPANP00000024527 ENSPANP00000024527 LOC110740452 LOC110740452 RAC3 RAC3 VAV2 VAV2 PPP3R1 PPP3R1 PPP3CB PPP3CB SH3BP2 SH3BP2 ITGAL ITGAL MAP2K1 MAP2K1 ENSPANP00000021653 ENSPANP00000021653 PRKCG PRKCG LOC101022480 LOC101022480 FAS FAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRF1Perforin 1. (555 aa)
ENSPANP00000019978Ig-like domain-containing protein. (153 aa)
KLRC1C-type lectin domain-containing protein. (233 aa)
SYKTyrosine-protein kinase. (635 aa)
SHC3SHC adaptor protein 3. (598 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
ENSPANP00000018668MHC_I-like_Ag-recog domain-containing protein. (232 aa)
IFNAR1Uncharacterized protein. (558 aa)
ERASES cell expressed Ras. (233 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (281 aa)
ULBP3MHC_I-like_Ag-recog domain-containing protein. (249 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
IFNGR2Fibronectin type-III domain-containing protein. (341 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
BIDBH3 interacting domain death agonist. (244 aa)
LOC103883952MHC_I-like_Ag-recog domain-containing protein. (244 aa)
ENSPANP00000017234MHC_I-like_Ag-recog domain-containing protein. (245 aa)
LOC101022300MHC_I-like_Ag-recog domain-containing protein. (335 aa)
ENSPANP00000017241MHC_I-like_Ag-recog domain-containing protein. (196 aa)
RAET1EMHC_I_2 domain-containing protein. (254 aa)
FYNTyrosine-protein kinase. (537 aa)
LOC101013367C-type lectin domain-containing protein. (285 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
LOC101023471Uncharacterized protein. (189 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
TNFRSF10BTNF receptor superfamily member 10b. (418 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
PIK3R2Uncharacterized protein. (721 aa)
HCSTHematopoietic cell signal transducer. (92 aa)
NCR1Natural cytotoxicity triggering receptor 1. (364 aa)
IFNAR2Interferon receptor 2, isoform 1 (Predicted). (516 aa)
NFATC1Nuclear factor of activated T cells 1. (930 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
CSDE1Cold shock domain containing E1. (844 aa)
KIR3DL3Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3. (316 aa)
HRASUncharacterized protein. (189 aa)
SHC2Uncharacterized protein. (567 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
ENSPANP00000001773Uncharacterized protein. (189 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity). (165 aa)
KLRG1Killer cell lectin like receptor G1. (189 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
NCR3Natural cytotoxicity triggering receptor 3. (201 aa)
SH2D1BSH2 domain containing 1B. (132 aa)
CD244CD244 molecule. (370 aa)
CSF2Granulocyte-macrophage colony-stimulating factor (Predicted). (144 aa)
TNFRSF10ATNF receptor superfamily member 10a. (306 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (281 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ICAM1Intercellular adhesion molecule 1. (532 aa)
KLRD1Killer cell lectin like receptor D1. (179 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (282 aa)
RAC1Rac family small GTPase 1. (211 aa)
ENSPANP00000009247Uncharacterized protein. (583 aa)
IFNB1Interferon beta 1. (187 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
ENSPANP00000010471Ig-like domain-containing protein. (148 aa)
KLRK1C-type lectin domain-containing protein. (216 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
LOC101011325Uncharacterized protein. (473 aa)
ENSPANP00000011803Ig-like domain-containing protein. (148 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
LATLinker for activation of T cells. (270 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
NCR2Natural cytotoxicity triggering receptor 2 (Predicted). (294 aa)
ITGB2Integrin beta. (919 aa)
RAC2Rac family small GTPase 2. (192 aa)
CEP152Centrosomal protein 152. (1706 aa)
SHC4SHC adaptor protein 4. (630 aa)
SRMSTyrosine-protein kinase. (492 aa)
PTK6Tyrosine-protein kinase. (451 aa)
KIR2DL4Uncharacterized protein. (479 aa)
ENSPANP00000014914Ig-like domain-containing protein. (319 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
IFNGR1Interferon gamma receptor 1. (488 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ICAM2Intercellular adhesion molecule 2. (275 aa)
LOC101017701MHC_I-like_Ag-recog domain-containing protein. (246 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
LOC101018055MHC_I-like_Ag-recog domain-containing protein. (255 aa)
LOC101002478Uncharacterized protein. (445 aa)
ENSPANP00000045653CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (195 aa)
TYROBPTYRO protein tyrosine kinase binding protein. (144 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC101016823Uncharacterized protein. (440 aa)
ENSPANP00000043887Uncharacterized protein. (82 aa)
LCKTyrosine-protein kinase. (545 aa)
RAF1Uncharacterized protein. (668 aa)
LOC101006295Uncharacterized protein. (518 aa)
CD247Uncharacterized protein. (165 aa)
TREML4Triggering receptor expressed on myeloid cells like 4. (138 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
LOC101002123Uncharacterized protein. (519 aa)
ENSPANP00000041355Uncharacterized protein. (489 aa)
ENSPANP00000041348Uncharacterized protein. (182 aa)
IFNA6Interferon alpha 6. (190 aa)
NFATC2Nuclear factor of activated T cells 2. (925 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (385 aa)
ENSPANP00000037764MHC_I-like_Ag-recog domain-containing protein. (245 aa)
ENSPANP00000036759Uncharacterized protein. (469 aa)
SHC1SHC adaptor protein 1. (601 aa)
LOC101019008Uncharacterized protein. (198 aa)
ENSPANP00000033846Uncharacterized protein. (542 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
VAV3Vav guanine nucleotide exchange factor 3. (872 aa)
FCGR3ALow affinity immunoglobulin gamma Fc region receptor III; Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Binds IgG1 and IgG2 (By similarity). (339 aa)
LOC101002253C-type lectin domain-containing protein. (238 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (624 aa)
ENSPANP00000030750Uncharacterized protein. (166 aa)
ENSPANP00000030153Ig-like domain-containing protein. (195 aa)
ENSPANP00000028630Uncharacterized protein. (441 aa)
CD48CD48 molecule. (250 aa)
FCER1GFc fragment of IgE receptor Ig. (112 aa)
ENSPANP00000026706Uncharacterized protein. (392 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
LOC101015094Ig-like domain-containing protein. (303 aa)
ENSPANP00000024527Uncharacterized protein. (397 aa)
LOC110740452MHC_I-like_Ag-recog domain-containing protein. (281 aa)
RAC3Rac family small GTPase 3. (192 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
PPP3R1Uncharacterized protein. (189 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
SH3BP2SH3 domain binding protein 2. (618 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1204 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ENSPANP00000021653Ig-like domain-containing protein. (170 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (701 aa)
LOC101022480Uncharacterized protein. (481 aa)
FASFas cell surface death receptor. (342 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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