STRINGSTRING
CYP4Z1 CYP4Z1 KRAS KRAS ENSPANP00000045653 ENSPANP00000045653 PRKACA PRKACA ENSPANP00000047699 ENSPANP00000047699 ITPR1 ITPR1 HTR2C HTR2C HRAS HRAS PRKACB PRKACB RAPGEF3 RAPGEF3 CSDE1 CSDE1 APP APP HTR1A HTR1A HTR3D HTR3D CYP4X1 CYP4X1 GABRB1 GABRB1 LOC101012275 LOC101012275 DDC DDC GNAI2 GNAI2 PLA2G4A PLA2G4A ARAF ARAF KCNJ3 KCNJ3 LOC101015175 LOC101015175 HTR1D HTR1D GNAI1 GNAI1 CASP3 CASP3 GNB3 GNB3 KCNJ5 KCNJ5 TPH2 TPH2 CACNA1S CACNA1S LOC101000991 LOC101000991 GNB4 GNB4 KCNJ9 KCNJ9 TPH1 TPH1 TRPC1 TRPC1 HTR1B HTR1B GNB1 GNB1 PLCB3 PLCB3 HTR2A HTR2A GNG7 GNG7 CACNA1A CACNA1A ENSPANP00000009247 ENSPANP00000009247 PTGS2 PTGS2 HTR1E HTR1E DUSP1 DUSP1 HTR6 HTR6 ITPR2 ITPR2 HTR3C HTR3C NRAS NRAS HTR1F HTR1F HTR3B HTR3B ITPR3 ITPR3 MAPK3 MAPK3 GNAO1 GNAO1 KCNJ6 KCNJ6 LOC101012978 LOC101012978 LOC101014319 LOC101014319 GNG13 GNG13 GNB5 GNB5 GNAS GNAS SLC18A1 SLC18A1 HTR2B HTR2B KCNN2 KCNN2 JMJD7 JMJD7 PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F PRKCA PRKCA PLCB1 PLCB1 LOC101001033 LOC101001033 CACNA1B CACNA1B ENSPANP00000017487 ENSPANP00000017487 GNAI3 GNAI3 GNG4 GNG4 GNGT1 GNGT1 ERAS ERAS HTR5A HTR5A BRAF BRAF GNB2 GNB2 MAOA MAOA MAOB MAOB GNG10 GNG10 GNAQ GNAQ ALOX15 ALOX15 PELP1 PELP1 LOC101012580 LOC101012580 ALOX12 ALOX12 ALOX12B ALOX12B SLC6A4 SLC6A4 GNGT2 GNGT2 ALOX5 ALOX5 CYP2C18 CYP2C18 ENSPANP00000020681 ENSPANP00000020681 LOC101023648 LOC101023648 PRKCG PRKCG MAP2K1 MAP2K1 LOC103887915 LOC103887915 CYP2C8 CYP2C8 GNG11 GNG11 GNG14 GNG14 CACNA1C CACNA1C LOC101014919 LOC101014919 PLA2G4C PLA2G4C MAPK1 MAPK1 ENSPANP00000026330 ENSPANP00000026330 CACNA1F CACNA1F GNG3 GNG3 LOC101007610 LOC101007610 HTR3A HTR3A GNG12 GNG12 PLCB4 PLCB4 GNG5 GNG5 ENSPANP00000034786 ENSPANP00000034786 PLCB2 PLCB2 GNG8 GNG8 PTGS1 PTGS1 GABRB3 GABRB3 HTR3E HTR3E PLA2G4B PLA2G4B KCND2 KCND2 HTR4 HTR4 CACNA1D CACNA1D GNG2 GNG2 ADCY5 ADCY5 GABRB2 GABRB2 RAF1 RAF1 ENSPANP00000001773 ENSPANP00000001773 ENSPANP00000043062 ENSPANP00000043062 PRKCB PRKCB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CYP4Z1Cytochrome P450 family 4 subfamily Z member 1. (329 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ENSPANP00000045653CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (195 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
ENSPANP00000047699G protein gamma domain-containing protein. (63 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2723 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
HRASUncharacterized protein. (189 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (338 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (925 aa)
CSDE1Cold shock domain containing E1. (844 aa)
APPAmyloid beta precursor protein. (770 aa)
HTR1A5-hydroxytryptamine receptor 1A. (422 aa)
HTR3D5-hydroxytryptamine receptor 3D. (442 aa)
CYP4X1Cytochrome P450 family 4 subfamily X member 1; Belongs to the cytochrome P450 family. (509 aa)
GABRB1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
LOC101012275Uncharacterized protein; Belongs to the cytochrome P450 family. (489 aa)
DDCDopa decarboxylase. (480 aa)
GNAI2G protein subunit alpha i2. (355 aa)
PLA2G4APhospholipase A2. (749 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
LOC101015175Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (502 aa)
HTR1D5-hydroxytryptamine receptor 1D. (335 aa)
GNAI1G protein subunit alpha i1. (422 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
GNB3G protein subunit beta 3. (340 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
TPH2Tryptophan hydroxylase 2. (496 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
LOC101000991Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNB4G protein subunit beta 4. (340 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (393 aa)
TPH1Tryptophan hydroxylase 1. (491 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (800 aa)
HTR1B5-hydroxytryptamine receptor 1B. (390 aa)
GNB1G protein subunit beta 1. (340 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
HTR2A5-hydroxytryptamine receptor 2A; Belongs to the G-protein coupled receptor 1 family. (450 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2477 aa)
ENSPANP00000009247Uncharacterized protein. (583 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
HTR1E5-hydroxytryptamine receptor 1E. (365 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
HTR65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (440 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
HTR3C5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (400 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
HTR1F5-hydroxytryptamine receptor 1F. (366 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2680 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
GNAO1G protein subunit alpha o1. (354 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
LOC101012978Uncharacterized protein. (401 aa)
LOC101014319Uncharacterized protein; Belongs to the cytochrome P450 family. (497 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
GNB5G protein subunit beta 5. (411 aa)
GNASGNAS complex locus. (1037 aa)
SLC18A1Solute carrier family 18 member A1. (525 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (844 aa)
JMJD7Jumonji domain containing 7. (316 aa)
PLA2G4EPhospholipase A2. (869 aa)
PLA2G4DPhospholipase A2. (817 aa)
PLA2G4FPhospholipase A2. (849 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1122 aa)
LOC101001033Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (490 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2341 aa)
ENSPANP00000017487Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNAI3G protein subunit alpha i3. (354 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ERASES cell expressed Ras. (233 aa)
HTR5A5-hydroxytryptamine receptor 5A. (357 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
GNB2G protein subunit beta 2. (340 aa)
MAOAAmine oxidase. (527 aa)
MAOBAmine oxidase. (504 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNAQG protein subunit alpha q. (384 aa)
ALOX15Arachidonate 15-lipoxygenase. (662 aa)
PELP1Proline, glutamate and leucine rich protein 1. (1180 aa)
LOC101012580Uncharacterized protein. (672 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (663 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (701 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
CYP2C18Cytochrome P450 family 2 subfamily C member 18; Belongs to the cytochrome P450 family. (490 aa)
ENSPANP00000020681Uncharacterized protein. (162 aa)
LOC101023648Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (701 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
LOC103887915Uncharacterized protein. (245 aa)
CYP2C8Cytochrome P450 family 2 subfamily C member 8; Belongs to the cytochrome P450 family. (490 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG14G protein subunit gamma 14. (94 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
LOC101014919Uncharacterized protein; Belongs to the cytochrome P450 family. (487 aa)
PLA2G4CPhospholipase A2 group IVC. (558 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ENSPANP00000026330Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1961 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC101007610G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (367 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (515 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSPANP00000034786Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (63 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1170 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (632 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (529 aa)
HTR3E5-hydroxytryptamine receptor 3E; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (461 aa)
PLA2G4BPhospholipase A2. (781 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
HTR45-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (428 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
RAF1Uncharacterized protein. (668 aa)
ENSPANP00000001773Uncharacterized protein. (189 aa)
ENSPANP00000043062Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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