STRINGSTRING
GEM GEM ARPC5 ARPC5 KRAS KRAS ENSPANP00000046766 ENSPANP00000046766 PPP1CC PPP1CC ENSPANP00000046380 ENSPANP00000046380 DIAPH2 DIAPH2 TMSB10 TMSB10 MYLK2 MYLK2 ENSPANP00000045565 ENSPANP00000045565 GSN GSN NCKAP1 NCKAP1 REM1 REM1 F2 F2 FGF17 FGF17 ENSPANP00000044488 ENSPANP00000044488 ENSPANP00000044332 ENSPANP00000044332 ITGB4 ITGB4 LIMK2 LIMK2 LIMK1 LIMK1 ENSPANP00000043411 ENSPANP00000043411 ITGB8 ITGB8 PTK2 PTK2 VIL1 VIL1 ENSPANP00000042655 ENSPANP00000042655 ITGA9 ITGA9 RAF1 RAF1 PFN1 PFN1 CFL1 CFL1 ENAH ENAH ENSPANP00000041348 ENSPANP00000041348 GIT1 GIT1 ENSPANP00000040819 ENSPANP00000040819 RHOA RHOA ENSPANP00000039822 ENSPANP00000039822 ZNF408 ZNF408 PXN PXN ENSPANP00000039285 ENSPANP00000039285 MAP2K2 MAP2K2 APC APC ENSPANP00000038985 ENSPANP00000038985 FN1 FN1 ABI2 ABI2 FGD3 FGD3 TIAM1 TIAM1 CDC42 CDC42 ZSCAN2 ZSCAN2 DIAPH3 DIAPH3 PPP1R12B PPP1R12B ENSPANP00000037673 ENSPANP00000037673 ENSPANP00000036814 ENSPANP00000036814 ARPC4 ARPC4 ACTN1 ACTN1 MYH14 MYH14 ITGA3 ITGA3 ENSPANP00000035674 ENSPANP00000035674 ITGB3 ITGB3 PPP1CB PPP1CB ACTG1 ACTG1 ENSPANP00000034674 ENSPANP00000034674 MYLPF MYLPF TMSB4X TMSB4X MYH11 MYH11 PIK3CB PIK3CB EZR EZR VAV3 VAV3 ITGB1 ITGB1 ENSPANP00000032942 ENSPANP00000032942 ARHGEF1 ARHGEF1 ENSPANP00000031871 ENSPANP00000031871 ITGA7 ITGA7 GNG12 GNG12 ENSPANP00000030957 ENSPANP00000030957 RRAD RRAD LPAR1 LPAR1 ENSPANP00000029710 ENSPANP00000029710 SRC SRC ENSPANP00000029311 ENSPANP00000029311 PIP5K1A PIP5K1A FGD4 FGD4 ENSPANP00000027582 ENSPANP00000027582 PIP5K1C PIP5K1C KNG1 KNG1 PAK3 PAK3 LPXN LPXN FGFR3 FGFR3 ARPC2 ARPC2 NEDD9 NEDD9 MAPK1 MAPK1 ENSPANP00000025644 ENSPANP00000025644 ARHGEF9 ARHGEF9 ENSPANP00000025174 ENSPANP00000025174 ENSPANP00000024607 ENSPANP00000024607 FGF9 FGF9 GNG14 GNG14 MYL10 MYL10 MSN MSN ARHGEF7 ARHGEF7 FGFR2 FGFR2 RAC3 RAC3 VAV2 VAV2 ENSPANP00000022961 ENSPANP00000022961 BCAR1 BCAR1 GNA12 GNA12 ITGAL ITGAL MAP2K1 MAP2K1 ENSPANP00000022011 ENSPANP00000022011 ENSPANP00000021931 ENSPANP00000021931 ENSPANP00000021774 ENSPANP00000021774 ROCK1 ROCK1 FGF8 FGF8 GPATCH8 GPATCH8 ITGA2B ITGA2B PIP4K2B PIP4K2B VCL VCL PDGFA PDGFA CXCL12 CXCL12 PIP4K2A PIP4K2A SSH2 SSH2 ITGA8 ITGA8 MYH10 MYH10 ITGAE ITGAE CRK CRK PIP5K1B PIP5K1B GOLGA2 GOLGA2 BRAF BRAF CAPG CAPG ITGA6 ITGA6 ITGA10 ITGA10 SPATA13 SPATA13 FGF2 FGF2 ERAS ERAS PFN2 PFN2 FGF23 FGF23 FGF3 FGF3 FGF19 FGF19 SOS1 SOS1 ENSPANP00000017205 ENSPANP00000017205 PAK5 PAK5 SOS2 SOS2 ENSPANP00000016806 ENSPANP00000016806 MYL9 MYL9 GNA13 GNA13 LRRC45 LRRC45 PAK6 PAK6 BAIAP2 BAIAP2 LOC101000032 LOC101000032 TUBGCP5 TUBGCP5 CYFIP1 CYFIP1 LOC101008267 LOC101008267 DOCK1 DOCK1 CRKL CRKL FGF18 FGF18 FGF20 FGF20 CXCR4 CXCR4 PDGFC PDGFC WASF1 WASF1 SCIN SCIN FGF22 FGF22 ARPC1B ARPC1B PIK3CD PIK3CD FGF6 FGF6 LOC101018600 LOC101018600 IQGAP1 IQGAP1 ZNF774 ZNF774 ENSPANP00000014356 ENSPANP00000014356 ENSPANP00000014293 ENSPANP00000014293 ITGA11 ITGA11 FGF7 FGF7 GALK2 GALK2 ENSPANP00000013998 ENSPANP00000013998 CFL2 CFL2 ENSPANP00000013909 ENSPANP00000013909 MYLK4 MYLK4 PDGFB PDGFB ARPC5L ARPC5L RAC2 RAC2 MYH9 MYH9 BDKRB2 BDKRB2 ROCK2 ROCK2 ITGB2 ITGB2 MYLK3 MYLK3 TGFB1I1 TGFB1I1 ITGAX ITGAX ITGAD ITGAD ITGAM ITGAM FGD2 FGD2 MAPK3 MAPK3 ENSPANP00000012445 ENSPANP00000012445 APC2 APC2 ENSPANP00000011993 ENSPANP00000011993 MYLK MYLK GPR55 GPR55 NCKAP1L NCKAP1L PIKFYVE PIKFYVE LOC101015485 LOC101015485 INSRR INSRR BDKRB1 BDKRB1 ENSPANP00000011336 ENSPANP00000011336 ACTL7B ACTL7B ENSPANP00000011252 ENSPANP00000011252 NRAS NRAS AADAC AADAC CCDC125 CCDC125 ACTL7A ACTL7A MYL12B MYL12B SSH3 SSH3 PPP1CA PPP1CA CHRM1 CHRM1 VILL VILL ACTB ACTB LPAR2 LPAR2 AADACL2 AADACL2 CYFIP2 CYFIP2 ACTRT2 ACTRT2 FGF5 FGF5 ENSPANP00000009247 ENSPANP00000009247 EGF EGF ITGB7 ITGB7 AVIL AVIL FGD1 FGD1 ARHGEF6 ARHGEF6 PAK4 PAK4 ARHGAP35 ARHGAP35 FGF1 FGF1 LOC100997172 LOC100997172 ENSPANP00000008217 ENSPANP00000008217 FGFR4 FGFR4 PDGFRB PDGFRB ITGA5 ITGA5 PIK3R2 PIK3R2 IQGAP3 IQGAP3 PDGFRA PDGFRA ITGAV ITGAV MRAS MRAS PAK1 PAK1 ARPC3 ARPC3 PFN4 PFN4 ITGA4 ITGA4 MYL2 MYL2 RAC1 RAC1 CHRM2 CHRM2 PDGFD PDGFD MYL12A MYL12A RRAS2 RRAS2 ITGB5 ITGB5 PIK3CA PIK3CA WASF2 WASF2 MYL5 MYL5 LOC100998064 LOC100998064 ANKRD13D ANKRD13D RRAS RRAS TIAM2 TIAM2 F2R F2R CHRM4 CHRM4 EGFR EGFR ARAF ARAF ARHGEF4 ARHGEF4 ITGA2 ITGA2 FGF21 FGF21 ENSPANP00000003487 ENSPANP00000003487 INS INS FGF16 FGF16 FGFR1 FGFR1 ACTL8 ACTL8 SLC9A1 SLC9A1 VAV1 VAV1 LOC101024285 LOC101024285 PIK3R3 PIK3R3 PAK2 PAK2 ENSPANP00000001773 ENSPANP00000001773 RDX RDX PIK3R1 PIK3R1 SSH1 SSH1 HRAS HRAS ITGB6 ITGB6 ENSPANP00000000945 ENSPANP00000000945 ITGA1 ITGA1 IQGAP2 IQGAP2 MOS MOS CHRM5 CHRM5 RHOC RHOC FGF10 FGF10 ACTN4 ACTN4 FGF4 FGF4 DIAPH1 DIAPH1 ARHGEF12 ARHGEF12 ACTRT1 ACTRT1 LPAR4 LPAR4 LPAR5 LPAR5 PPP1R12A PPP1R12A PPP1R12C PPP1R12C NPM1 NPM1 PIP4K2C PIP4K2C CSDE1 CSDE1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ENSPANP00000046766Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (153 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa)
ENSPANP00000046380Uncharacterized protein. (232 aa)
DIAPH2Diaphanous related formin 2. (1099 aa)
TMSB10Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
ENSPANP00000045565Uncharacterized protein. (44 aa)
GSNGelsolin. (809 aa)
NCKAP1NCK associated protein 1. (1137 aa)
REM1RRAD and GEM like GTPase 1. (515 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (626 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ENSPANP00000044488WH1 domain-containing protein. (90 aa)
ENSPANP00000044332Uncharacterized protein. (242 aa)
ITGB4Integrin beta. (1752 aa)
LIMK2LIM domain kinase 2. (638 aa)
LIMK1LIM domain kinase 1. (677 aa)
ENSPANP00000043411Uncharacterized protein. (233 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (824 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa)
VIL1Villin 1. (830 aa)
ENSPANP00000042655Uncharacterized protein. (60 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1032 aa)
RAF1Uncharacterized protein. (668 aa)
PFN1Profilin; Belongs to the profilin family. (167 aa)
CFL1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (196 aa)
ENAHENAH actin regulator. (789 aa)
ENSPANP00000041348Uncharacterized protein. (182 aa)
GIT1GIT ArfGAP 1. (770 aa)
ENSPANP00000040819Uncharacterized protein. (92 aa)
RHOARas homolog family member A. (193 aa)
ENSPANP00000039822ADF-H domain-containing protein. (135 aa)
ZNF408Zinc finger protein 408. (719 aa)
PXNPaxillin. (1082 aa)
ENSPANP00000039285Uncharacterized protein. (241 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (385 aa)
APCAPC regulator of WNT signaling pathway. (2871 aa)
ENSPANP00000038985Uncharacterized protein; Belongs to the actin family. (362 aa)
FN1Fibronectin 1. (2477 aa)
ABI2Abl interactor 2. (513 aa)
FGD3FYVE, RhoGEF and PH domain containing 3. (792 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1577 aa)
CDC42Cell division cycle 42. (191 aa)
ZSCAN2Zinc finger and SCAN domain containing 2. (642 aa)
DIAPH3Diaphanous related formin 3. (1193 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (1045 aa)
ENSPANP00000037673WD_REPEATS_REGION domain-containing protein. (336 aa)
ENSPANP00000036814ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (209 aa)
ARPC4Uncharacterized protein. (279 aa)
ACTN1Actinin alpha 1. (930 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
ENSPANP00000035674ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (158 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (328 aa)
ACTG1Actin gamma 1. (377 aa)
ENSPANP00000034674Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (169 aa)
MYLPFMyosin light chain, phosphorylatable, fast skeletal muscle. (198 aa)
TMSB4XThymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1985 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
EZREzrin. (603 aa)
VAV3Vav guanine nucleotide exchange factor 3. (872 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
ENSPANP00000032942Uncharacterized protein. (182 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (998 aa)
ENSPANP00000031871Uncharacterized protein. (249 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ENSPANP00000030957Uncharacterized protein. (313 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
LPAR1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ENSPANP00000029710Uncharacterized protein. (207 aa)
SRCTyrosine-protein kinase. (644 aa)
ENSPANP00000029311Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (130 aa)
PIP5K1APIPK domain-containing protein. (578 aa)
FGD4FYVE, RhoGEF and PH domain containing 4. (931 aa)
ENSPANP00000027582Uncharacterized protein. (344 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (708 aa)
KNG1Kininogen 1. (644 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
FGFR3Fibroblast growth factor receptor. (775 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ENSPANP00000025644Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (161 aa)
ARHGEF9Cdc42 guanine nucleotide exchange factor 9. (552 aa)
ENSPANP00000025174Uncharacterized protein. (317 aa)
ENSPANP00000024607Uncharacterized protein. (225 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
GNG14G protein subunit gamma 14. (94 aa)
MYL10Myosin light chain 10. (226 aa)
MSNMoesin. (581 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
RAC3Rac family small GTPase 3. (192 aa)
VAV2Vav guanine nucleotide exchange factor 2. (878 aa)
ENSPANP00000022961Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (147 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
GNA12G protein subunit alpha 12. (381 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1204 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ENSPANP00000022011Uncharacterized protein. (153 aa)
ENSPANP00000021931Uncharacterized protein. (175 aa)
ENSPANP00000021774PIPK domain-containing protein. (502 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
GPATCH8G-patch domain containing 8. (1501 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
VCLVinculin. (1134 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (406 aa)
SSH2Slingshot protein phosphatase 2. (1450 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
ITGAEIntegrin subunit alpha E; Belongs to the integrin alpha chain family. (1178 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (540 aa)
GOLGA2Golgin A2. (1005 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
CAPGCapping actin protein, gelsolin like. (348 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1088 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1168 aa)
SPATA13Uncharacterized protein. (1273 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
ERASES cell expressed Ras. (233 aa)
PFN2Profilin; Belongs to the profilin family. (188 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
ENSPANP00000017205Uncharacterized protein. (250 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
ENSPANP00000016806Uncharacterized protein. (324 aa)
MYL9Myosin light chain 9. (172 aa)
GNA13G protein subunit alpha 13. (377 aa)
LRRC45Leucine rich repeat containing 45. (675 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
BAIAP2BAI1 associated protein 2. (552 aa)
LOC101000032Uncharacterized protein. (641 aa)
TUBGCP5Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (972 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
LOC101008267Uncharacterized protein. (399 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
CXCR4C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (355 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
WASF1WASP family member 1. (559 aa)
SCINScinderin. (715 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (376 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC101018600Uncharacterized protein. (624 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1696 aa)
ZNF774Zinc finger protein 774. (483 aa)
ENSPANP00000014356Uncharacterized protein. (488 aa)
ENSPANP00000014293Uncharacterized protein. (599 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1176 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
GALK2Galactokinase 2. (458 aa)
ENSPANP00000013998Uncharacterized protein. (124 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
ENSPANP00000013909Profilin; Belongs to the profilin family. (179 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (443 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (159 aa)
RAC2Rac family small GTPase 2. (192 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1962 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
ITGB2Integrin beta. (919 aa)
MYLK3Myosin light chain kinase 3. (819 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1163 aa)
ITGADIntegrin subunit alpha D; Belongs to the integrin alpha chain family. (1129 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
FGD2FYVE, RhoGEF and PH domain containing 2. (655 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ENSPANP00000012445Uncharacterized protein; Belongs to the actin family. (380 aa)
APC2APC regulator of WNT signaling pathway 2. (2301 aa)
ENSPANP00000011993Nucleoplasmin domain-containing protein. (225 aa)
MYLKMyosin light chain kinase. (1875 aa)
GPR55G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (319 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
LOC101015485Uncharacterized protein. (746 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
BDKRB1Bradykinin receptor B1. (282 aa)
ENSPANP00000011336Uncharacterized protein; Belongs to the actin family. (347 aa)
ACTL7BActin like 7B; Belongs to the actin family. (415 aa)
ENSPANP00000011252G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (378 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
AADACArylacetamide deacetylase. (399 aa)
CCDC125Coiled-coil domain containing 125. (419 aa)
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)
MYL12BMyosin light chain 12B. (172 aa)
SSH3Slingshot protein phosphatase 3. (657 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
VILLVillin like. (855 aa)
ACTBActin beta. (379 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
AADACL2Arylacetamide deacetylase like 2. (401 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
ACTRT2Actin related protein T2; Belongs to the actin family. (377 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
ENSPANP00000009247Uncharacterized protein. (583 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1161 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
AVILAdvillin. (819 aa)
FGD1FYVE, RhoGEF and PH domain containing 1. (961 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (771 aa)
PAK4Non-specific serine/threonine protein kinase. (597 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
LOC100997172Uncharacterized protein. (596 aa)
ENSPANP00000008217Nucleoplasmin domain-containing protein. (283 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
PIK3R2Uncharacterized protein. (721 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1632 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
MRASMuscle RAS oncogene homolog. (208 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
PFN4Profilin; Belongs to the profilin family. (109 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1017 aa)
MYL2Myosin light chain 2. (166 aa)
RAC1Rac family small GTPase 1. (211 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
PDGFDPlatelet derived growth factor D. (303 aa)
MYL12AMyosin light chain 12A. (177 aa)
RRAS2RAS related 2. (204 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
WASF2WASP family member 2. (498 aa)
MYL5Myosin light chain 5. (173 aa)
LOC100998064Uncharacterized protein. (579 aa)
ANKRD13DAnkyrin repeat domain 13D. (605 aa)
RRASRAS related. (218 aa)
TIAM2T cell lymphoma invasion and metastasis 2. (1725 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (479 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
ARHGEF4Uncharacterized protein. (1816 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1161 aa)
FGF21Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family. (174 aa)
ENSPANP00000003487Uncharacterized protein. (44 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGFR1Fibroblast growth factor receptor. (853 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
LOC101024285Uncharacterized protein. (191 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
ENSPANP00000001773Uncharacterized protein. (189 aa)
RDXRadixin. (604 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
SSH1Slingshot protein phosphatase 1. (1050 aa)
HRASUncharacterized protein. (189 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
ENSPANP00000000945Uncharacterized protein. (301 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1164 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1543 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (346 aa)
CHRM5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
RHOCRas homolog family member C. (193 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ACTN4Actinin alpha 4. (931 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
DIAPH1Diaphanous related formin 1. (1244 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1517 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
LPAR4Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (370 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1029 aa)
PPP1R12CProtein phosphatase 1 regulatory subunit. (783 aa)
NPM1Nucleophosmin 1. (294 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
CSDE1Cold shock domain containing E1. (844 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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