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| | GEM | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa) |
| | ARPC5 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | ENSPANP00000046766 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (153 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (341 aa) |
| | ENSPANP00000046380 | Uncharacterized protein. (232 aa) |
| | DIAPH2 | Diaphanous related formin 2. (1099 aa) |
| | TMSB10 | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa) |
| | MYLK2 | Myosin light chain kinase 2. (595 aa) |
| | ENSPANP00000045565 | Uncharacterized protein. (44 aa) |
| | GSN | Gelsolin. (809 aa) |
| | NCKAP1 | NCK associated protein 1. (1137 aa) |
| | REM1 | RRAD and GEM like GTPase 1. (515 aa) |
| | F2 | Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (626 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | ENSPANP00000044488 | WH1 domain-containing protein. (90 aa) |
| | ENSPANP00000044332 | Uncharacterized protein. (242 aa) |
| | ITGB4 | Integrin beta. (1752 aa) |
| | LIMK2 | LIM domain kinase 2. (638 aa) |
| | LIMK1 | LIM domain kinase 1. (677 aa) |
| | ENSPANP00000043411 | Uncharacterized protein. (233 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (824 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa) |
| | VIL1 | Villin 1. (830 aa) |
| | ENSPANP00000042655 | Uncharacterized protein. (60 aa) |
| | ITGA9 | Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1032 aa) |
| | RAF1 | Uncharacterized protein. (668 aa) |
| | PFN1 | Profilin; Belongs to the profilin family. (167 aa) |
| | CFL1 | ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (196 aa) |
| | ENAH | ENAH actin regulator. (789 aa) |
| | ENSPANP00000041348 | Uncharacterized protein. (182 aa) |
| | GIT1 | GIT ArfGAP 1. (770 aa) |
| | ENSPANP00000040819 | Uncharacterized protein. (92 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | ENSPANP00000039822 | ADF-H domain-containing protein. (135 aa) |
| | ZNF408 | Zinc finger protein 408. (719 aa) |
| | PXN | Paxillin. (1082 aa) |
| | ENSPANP00000039285 | Uncharacterized protein. (241 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (385 aa) |
| | APC | APC regulator of WNT signaling pathway. (2871 aa) |
| | ENSPANP00000038985 | Uncharacterized protein; Belongs to the actin family. (362 aa) |
| | FN1 | Fibronectin 1. (2477 aa) |
| | ABI2 | Abl interactor 2. (513 aa) |
| | FGD3 | FYVE, RhoGEF and PH domain containing 3. (792 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1577 aa) |
| | CDC42 | Cell division cycle 42. (191 aa) |
| | ZSCAN2 | Zinc finger and SCAN domain containing 2. (642 aa) |
| | DIAPH3 | Diaphanous related formin 3. (1193 aa) |
| | PPP1R12B | Protein phosphatase 1 regulatory subunit. (1045 aa) |
| | ENSPANP00000037673 | WD_REPEATS_REGION domain-containing protein. (336 aa) |
| | ENSPANP00000036814 | ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (209 aa) |
| | ARPC4 | Uncharacterized protein. (279 aa) |
| | ACTN1 | Actinin alpha 1. (930 aa) |
| | MYH14 | Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa) |
| | ITGA3 | Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa) |
| | ENSPANP00000035674 | ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (158 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (788 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (328 aa) |
| | ACTG1 | Actin gamma 1. (377 aa) |
| | ENSPANP00000034674 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (169 aa) |
| | MYLPF | Myosin light chain, phosphorylatable, fast skeletal muscle. (198 aa) |
| | TMSB4X | Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa) |
| | MYH11 | Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1985 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | EZR | Ezrin. (603 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (872 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (801 aa) |
| | ENSPANP00000032942 | Uncharacterized protein. (182 aa) |
| | ARHGEF1 | Rho guanine nucleotide exchange factor 1. (998 aa) |
| | ENSPANP00000031871 | Uncharacterized protein. (249 aa) |
| | ITGA7 | Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | ENSPANP00000030957 | Uncharacterized protein. (313 aa) |
| | RRAD | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa) |
| | LPAR1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (353 aa) |
| | ENSPANP00000029710 | Uncharacterized protein. (207 aa) |
| | SRC | Tyrosine-protein kinase. (644 aa) |
| | ENSPANP00000029311 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (130 aa) |
| | PIP5K1A | PIPK domain-containing protein. (578 aa) |
| | FGD4 | FYVE, RhoGEF and PH domain containing 4. (931 aa) |
| | ENSPANP00000027582 | Uncharacterized protein. (344 aa) |
| | PIP5K1C | Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (708 aa) |
| | KNG1 | Kininogen 1. (644 aa) |
| | PAK3 | P21 (RAC1) activated kinase 3. (580 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (775 aa) |
| | ARPC2 | Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa) |
| | NEDD9 | Neural precursor cell expressed, developmentally down-regulated 9. (839 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | ENSPANP00000025644 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (161 aa) |
| | ARHGEF9 | Cdc42 guanine nucleotide exchange factor 9. (552 aa) |
| | ENSPANP00000025174 | Uncharacterized protein. (317 aa) |
| | ENSPANP00000024607 | Uncharacterized protein. (225 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | GNG14 | G protein subunit gamma 14. (94 aa) |
| | MYL10 | Myosin light chain 10. (226 aa) |
| | MSN | Moesin. (581 aa) |
| | ARHGEF7 | Rho guanine nucleotide exchange factor 7. (862 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (840 aa) |
| | RAC3 | Rac family small GTPase 3. (192 aa) |
| | VAV2 | Vav guanine nucleotide exchange factor 2. (878 aa) |
| | ENSPANP00000022961 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (147 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (916 aa) |
| | GNA12 | G protein subunit alpha 12. (381 aa) |
| | ITGAL | Integrin subunit alpha L; Belongs to the integrin alpha chain family. (1204 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | ENSPANP00000022011 | Uncharacterized protein. (153 aa) |
| | ENSPANP00000021931 | Uncharacterized protein. (175 aa) |
| | ENSPANP00000021774 | PIPK domain-containing protein. (502 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | GPATCH8 | G-patch domain containing 8. (1501 aa) |
| | ITGA2B | Integrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa) |
| | PIP4K2B | Phosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa) |
| | VCL | Vinculin. (1134 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa) |
| | PIP4K2A | Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (406 aa) |
| | SSH2 | Slingshot protein phosphatase 2. (1450 aa) |
| | ITGA8 | Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa) |
| | MYH10 | Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa) |
| | ITGAE | Integrin subunit alpha E; Belongs to the integrin alpha chain family. (1178 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | PIP5K1B | Phosphatidylinositol-4-phosphate 5-kinase type 1 beta. (540 aa) |
| | GOLGA2 | Golgin A2. (1005 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (763 aa) |
| | CAPG | Capping actin protein, gelsolin like. (348 aa) |
| | ITGA6 | Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1088 aa) |
| | ITGA10 | Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1168 aa) |
| | SPATA13 | Uncharacterized protein. (1273 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | PFN2 | Profilin; Belongs to the profilin family. (188 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa) |
| | ENSPANP00000017205 | Uncharacterized protein. (250 aa) |
| | PAK5 | Non-specific serine/threonine protein kinase. (719 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | ENSPANP00000016806 | Uncharacterized protein. (324 aa) |
| | MYL9 | Myosin light chain 9. (172 aa) |
| | GNA13 | G protein subunit alpha 13. (377 aa) |
| | LRRC45 | Leucine rich repeat containing 45. (675 aa) |
| | PAK6 | Non-specific serine/threonine protein kinase. (681 aa) |
| | BAIAP2 | BAI1 associated protein 2. (552 aa) |
| | LOC101000032 | Uncharacterized protein. (641 aa) |
| | TUBGCP5 | Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (972 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa) |
| | LOC101008267 | Uncharacterized protein. (399 aa) |
| | DOCK1 | Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | CXCR4 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (355 aa) |
| | PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) |
| | WASF1 | WASP family member 1. (559 aa) |
| | SCIN | Scinderin. (715 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa) |
| | ARPC1B | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (376 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | LOC101018600 | Uncharacterized protein. (624 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1696 aa) |
| | ZNF774 | Zinc finger protein 774. (483 aa) |
| | ENSPANP00000014356 | Uncharacterized protein. (488 aa) |
| | ENSPANP00000014293 | Uncharacterized protein. (599 aa) |
| | ITGA11 | Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1176 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | GALK2 | Galactokinase 2. (458 aa) |
| | ENSPANP00000013998 | Uncharacterized protein. (124 aa) |
| | CFL2 | Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa) |
| | ENSPANP00000013909 | Profilin; Belongs to the profilin family. (179 aa) |
| | MYLK4 | Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (443 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | ARPC5L | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (159 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | MYH9 | Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1962 aa) |
| | BDKRB2 | Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (391 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa) |
| | ITGB2 | Integrin beta. (919 aa) |
| | MYLK3 | Myosin light chain kinase 3. (819 aa) |
| | TGFB1I1 | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa) |
| | ITGAX | Integrin subunit alpha X; Belongs to the integrin alpha chain family. (1163 aa) |
| | ITGAD | Integrin subunit alpha D; Belongs to the integrin alpha chain family. (1129 aa) |
| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa) |
| | FGD2 | FYVE, RhoGEF and PH domain containing 2. (655 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | ENSPANP00000012445 | Uncharacterized protein; Belongs to the actin family. (380 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2301 aa) |
| | ENSPANP00000011993 | Nucleoplasmin domain-containing protein. (225 aa) |
| | MYLK | Myosin light chain kinase. (1875 aa) |
| | GPR55 | G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (319 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1134 aa) |
| | PIKFYVE | Phosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa) |
| | LOC101015485 | Uncharacterized protein. (746 aa) |
| | INSRR | Tyrosine-protein kinase receptor. (1301 aa) |
| | BDKRB1 | Bradykinin receptor B1. (282 aa) |
| | ENSPANP00000011336 | Uncharacterized protein; Belongs to the actin family. (347 aa) |
| | ACTL7B | Actin like 7B; Belongs to the actin family. (415 aa) |
| | ENSPANP00000011252 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | AADAC | Arylacetamide deacetylase. (399 aa) |
| | CCDC125 | Coiled-coil domain containing 125. (419 aa) |
| | ACTL7A | Actin like 7A; Belongs to the actin family. (435 aa) |
| | MYL12B | Myosin light chain 12B. (172 aa) |
| | SSH3 | Slingshot protein phosphatase 3. (657 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) |
| | CHRM1 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa) |
| | VILL | Villin like. (855 aa) |
| | ACTB | Actin beta. (379 aa) |
| | LPAR2 | Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa) |
| | AADACL2 | Arylacetamide deacetylase like 2. (401 aa) |
| | CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa) |
| | ACTRT2 | Actin related protein T2; Belongs to the actin family. (377 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa) |
| | ENSPANP00000009247 | Uncharacterized protein. (583 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1161 aa) |
| | ITGB7 | Integrin beta; Belongs to the integrin beta chain family. (798 aa) |
| | AVIL | Advillin. (819 aa) |
| | FGD1 | FYVE, RhoGEF and PH domain containing 1. (961 aa) |
| | ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor 6. (771 aa) |
| | PAK4 | Non-specific serine/threonine protein kinase. (597 aa) |
| | ARHGAP35 | Rho GTPase activating protein 35. (1499 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | LOC100997172 | Uncharacterized protein. (596 aa) |
| | ENSPANP00000008217 | Nucleoplasmin domain-containing protein. (283 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (802 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa) |
| | PIK3R2 | Uncharacterized protein. (721 aa) |
| | IQGAP3 | IQ motif containing GTPase activating protein 3. (1632 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa) |
| | MRAS | Muscle RAS oncogene homolog. (208 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (545 aa) |
| | ARPC3 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa) |
| | PFN4 | Profilin; Belongs to the profilin family. (109 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1017 aa) |
| | MYL2 | Myosin light chain 2. (166 aa) |
| | RAC1 | Rac family small GTPase 1. (211 aa) |
| | CHRM2 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa) |
| | PDGFD | Platelet derived growth factor D. (303 aa) |
| | MYL12A | Myosin light chain 12A. (177 aa) |
| | RRAS2 | RAS related 2. (204 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (799 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | WASF2 | WASP family member 2. (498 aa) |
| | MYL5 | Myosin light chain 5. (173 aa) |
| | LOC100998064 | Uncharacterized protein. (579 aa) |
| | ANKRD13D | Ankyrin repeat domain 13D. (605 aa) |
| | RRAS | RAS related. (218 aa) |
| | TIAM2 | T cell lymphoma invasion and metastasis 2. (1725 aa) |
| | F2R | Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa) |
| | CHRM4 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (479 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (606 aa) |
| | ARHGEF4 | Uncharacterized protein. (1816 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1161 aa) |
| | FGF21 | Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family. (174 aa) |
| | ENSPANP00000003487 | Uncharacterized protein. (44 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (853 aa) |
| | ACTL8 | Actin like 8; Belongs to the actin family. (366 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (845 aa) |
| | LOC101024285 | Uncharacterized protein. (191 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | ENSPANP00000001773 | Uncharacterized protein. (189 aa) |
| | RDX | Radixin. (604 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | SSH1 | Slingshot protein phosphatase 1. (1050 aa) |
| | HRAS | Uncharacterized protein. (189 aa) |
| | ITGB6 | Integrin beta; Belongs to the integrin beta chain family. (788 aa) |
| | ENSPANP00000000945 | Uncharacterized protein. (301 aa) |
| | ITGA1 | Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1164 aa) |
| | IQGAP2 | IQ motif containing GTPase activating protein 2. (1543 aa) |
| | MOS | MOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (346 aa) |
| | CHRM5 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa) |
| | RHOC | Ras homolog family member C. (193 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | ACTN4 | Actinin alpha 4. (931 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | DIAPH1 | Diaphanous related formin 1. (1244 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1517 aa) |
| | ACTRT1 | Actin related protein T1; Belongs to the actin family. (375 aa) |
| | LPAR4 | Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (370 aa) |
| | LPAR5 | Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | PPP1R12A | Protein phosphatase 1 regulatory subunit. (1029 aa) |
| | PPP1R12C | Protein phosphatase 1 regulatory subunit. (783 aa) |
| | NPM1 | Nucleophosmin 1. (294 aa) |
| | PIP4K2C | Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
