STRINGSTRING
PLD2 PLD2 GNAQ GNAQ ERAS ERAS ADCY4 ADCY4 SOS1 SOS1 PLCB1 PLCB1 GNRH2 GNRH2 SOS2 SOS2 MAP2K6 MAP2K6 PRKCA PRKCA PLA2G4F PLA2G4F PLA2G4D PLA2G4D PLA2G4E PLA2G4E JMJD7 JMJD7 GRB2 GRB2 MMP14 MMP14 MAP3K4 MAP3K4 CALM1 CALM1 LOC101008793 LOC101008793 GNAS GNAS CALML4 CALML4 ADCY9 ADCY9 MAPK11 MAPK11 MAPK12 MAPK12 ATF4 ATF4 MMP2 MMP2 ADCY7 ADCY7 MAPK14 MAPK14 MAPK3 MAPK3 ITPR3 ITPR3 CALM3 CALM3 PRKCD PRKCD NRAS NRAS MAPK9 MAPK9 ELK1 ELK1 MAP3K1 MAP3K1 GEM GEM ITPR2 ITPR2 LHB LHB ENSPANP00000009247 ENSPANP00000009247 GNA11 GNA11 CALML3 CALML3 PLD1 PLD1 PLCB3 PLCB3 CAMK2A CAMK2A ADCY1 ADCY1 CACNA1S CACNA1S HBEGF HBEGF ADCY8 ADCY8 PTRHD1 PTRHD1 EGFR EGFR PLA2G4A PLA2G4A CGB CGB ELK3 ELK3 CSDE1 CSDE1 FSHB FSHB LOC101024285 LOC101024285 ARSI ARSI GNRHR GNRHR ENSPANP00000001773 ENSPANP00000001773 ADCY3 ADCY3 PTK2B PTK2B HRAS HRAS PRKACB PRKACB ADCY2 ADCY2 PRKACA PRKACA KRAS KRAS CAMK2B CAMK2B CAMK2D CAMK2D ITPR1 ITPR1 REM1 REM1 PRKCB PRKCB PVALEF PVALEF MAPK13 MAPK13 RAF1 RAF1 MAP3K2 MAP3K2 GNRH1 GNRH1 ADCY5 ADCY5 CGA CGA MAP2K7 MAP2K7 CACNA1D CACNA1D MAP2K2 MAP2K2 ADCY6 ADCY6 MAPK10 MAPK10 CDC42 CDC42 ENSPANP00000038051 ENSPANP00000038051 PTX3 PTX3 PLA2G4B PLA2G4B PLCB2 PLCB2 CALML6 CALML6 MAPK8 MAPK8 ENSPANP00000033457 ENSPANP00000033457 ENSPANP00000032942 ENSPANP00000032942 PLCB4 PLCB4 MAP3K3 MAP3K3 RRAD RRAD ENSPANP00000030371 ENSPANP00000030371 LHB-2 LHB-2 ENSPANP00000029629 ENSPANP00000029629 SRC SRC CALM2 CALM2 CACNA1F CACNA1F MAPK1 MAPK1 PLA2G4C PLA2G4C LOC101024083 LOC101024083 CACNA1C CACNA1C LOC103887915 LOC103887915 EGR1 EGR1 MAP2K1 MAP2K1 ENSPANP00000022011 ENSPANP00000022011 ENSPANP00000021931 ENSPANP00000021931 ENSPANP00000021624 ENSPANP00000021624 EFCAB3 EFCAB3 EFCAB13 EFCAB13 CAMK2G CAMK2G MAP2K3 MAP2K3 MAPK7 MAPK7 MAP2K4 MAP2K4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLD2Phospholipase. (933 aa)
GNAQG protein subunit alpha q. (384 aa)
ERASES cell expressed Ras. (233 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1122 aa)
GNRH2Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (120 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PLA2G4FPhospholipase A2. (849 aa)
PLA2G4DPhospholipase A2. (817 aa)
PLA2G4EPhospholipase A2. (869 aa)
JMJD7Jumonji domain containing 7. (316 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1818 aa)
CALM1Calmodulin 1. (149 aa)
LOC101008793G_PROTEIN_RECEP_F1_2 domain-containing protein. (379 aa)
GNASGNAS complex locus. (1037 aa)
CALML4Calmodulin like 4. (194 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
ATF4Activating transcription factor 4. (351 aa)
MMP2Matrix metallopeptidase 2. (660 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2680 aa)
CALM3Calmodulin 1; Belongs to the calmodulin family. (149 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ELK1ETS domain-containing protein. (428 aa)
MAP3K1Uncharacterized protein. (1508 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
LHBChoriogonadotropin subunit beta; Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. (165 aa)
ENSPANP00000009247Uncharacterized protein. (583 aa)
GNA11G protein subunit alpha 11. (359 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
PLD1Phospholipase. (1074 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
PLA2G4APhospholipase A2. (749 aa)
CGBCys_knot domain-containing protein. (148 aa)
ELK3ETS transcription factor ELK3. (407 aa)
CSDE1Cold shock domain containing E1. (844 aa)
FSHBFollicle stimulating hormone subunit beta. (129 aa)
LOC101024285Uncharacterized protein. (191 aa)
ARSIArylsulfatase family member I. (569 aa)
GNRHRGonadotropin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (328 aa)
ENSPANP00000001773Uncharacterized protein. (189 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
HRASUncharacterized protein. (189 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (338 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (666 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2723 aa)
REM1RRAD and GEM like GTPase 1. (515 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PVALEFParvalbumin like EF-hand containing. (133 aa)
MAPK13Mitogen-activated protein kinase. (386 aa)
RAF1Uncharacterized protein. (668 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (634 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (150 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (446 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (385 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
MAPK10Mitogen-activated protein kinase. (467 aa)
CDC42Cell division cycle 42. (191 aa)
ENSPANP00000038051Cys_knot domain-containing protein. (155 aa)
PTX3Pentraxin 3. (392 aa)
PLA2G4BPhospholipase A2. (781 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1170 aa)
CALML6Calmodulin like 6. (181 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSPANP00000033457Uncharacterized protein; Belongs to the calmodulin family. (99 aa)
ENSPANP00000032942Uncharacterized protein. (182 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (658 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
ENSPANP00000030371Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
LHB-2Cys_knot domain-containing protein. (165 aa)
ENSPANP00000029629ETS domain-containing protein. (384 aa)
SRCTyrosine-protein kinase. (644 aa)
CALM2Calmodulin 2. (149 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1961 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PLA2G4CPhospholipase A2 group IVC. (558 aa)
LOC101024083Cys_knot domain-containing protein. (165 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2186 aa)
LOC103887915Uncharacterized protein. (245 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ENSPANP00000022011Uncharacterized protein. (153 aa)
ENSPANP00000021931Uncharacterized protein. (175 aa)
ENSPANP00000021624BZIP domain-containing protein. (322 aa)
EFCAB3EF-hand calcium binding domain 3. (488 aa)
EFCAB13EF-hand calcium binding domain 13. (973 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (556 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (394 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (466 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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