STRINGSTRING
ADIPOR1 ADIPOR1 ACACB ACACB PTPN11 PTPN11 NPY NPY NFKBIB NFKBIB PRKAA2 PRKAA2 LEP LEP RXRG RXRG PRKAG3 PRKAG3 ACSL3 ACSL3 AKT3 AKT3 LEPR LEPR ACSL1 ACSL1 PRKAG1 PRKAG1 ENSPANP00000022451 ENSPANP00000022451 IRS4 IRS4 CPT1B CPT1B ADIPOQ ADIPOQ ENSPANP00000028630 ENSPANP00000028630 PCK2 PCK2 SLC2A1 SLC2A1 NFKBIA NFKBIA RXRA RXRA MAPK8 MAPK8 ENSPANP00000033846 ENSPANP00000033846 ENSPANP00000036798 ENSPANP00000036798 STAT3 STAT3 CD36 CD36 JAK2 JAK2 PRKAA1 PRKAA1 AKT2 AKT2 RELA RELA ENSPANP00000044800 ENSPANP00000044800 ENSPANP00000041355 ENSPANP00000041355 SLC2A14 SLC2A14 PCK1 PCK1 PRKCQ PRKCQ IKBKB IKBKB MAPK10 MAPK10 IRS2 IRS2 CHUK CHUK G6PC3 G6PC3 G6PC G6PC SLC2A4 SLC2A4 PPARGC1A PPARGC1A SLC2A3 SLC2A3 MTOR MTOR TRAF2 TRAF2 ACSBG1 ACSBG1 PPARA PPARA AKT1 AKT1 TRADD TRADD NFKBIE NFKBIE RXRB RXRB TNF TNF AGRP AGRP PRKAG2 PRKAG2 MAPK9 MAPK9 NFKB1 NFKB1 PRKAB2 PRKAB2 ACSBG2 ACSBG2 CPT1C CPT1C ACSL6 ACSL6 STK11 STK11 TNFRSF1B TNFRSF1B CAMKK2 CAMKK2 TNFRSF1A TNFRSF1A CPT1A CPT1A ACSL5 ACSL5 POMC POMC SOCS3 SOCS3 ADIPOR2 ADIPOR2 ACSL4 ACSL4 PRKAB1 PRKAB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADIPOR1Adiponectin receptor 1. (375 aa)
ACACBAcetyl-CoA carboxylase beta. (2458 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
NPYNeuropeptide Y. (97 aa)
NFKBIBNFKB inhibitor beta. (356 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
RXRGRetinoid X receptor gamma. (463 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LEPRLeptin receptor. (1163 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (698 aa)
PRKAG1Protein kinase AMP-activated non-catalytic subunit gamma 1. (340 aa)
ENSPANP00000022451acidPPc domain-containing protein. (153 aa)
IRS4Insulin receptor substrate 4. (1250 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (275 aa)
ENSPANP00000028630Uncharacterized protein. (441 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (645 aa)
SLC2A1MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (504 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
RXRARetinoid X receptor alpha. (522 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSPANP00000033846Uncharacterized protein. (542 aa)
ENSPANP00000036798MFS domain-containing protein. (228 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
JAK2Tyrosine-protein kinase. (1133 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
RELARELA proto-oncogene, NF-kB subunit. (476 aa)
ENSPANP00000044800MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (457 aa)
ENSPANP00000041355Uncharacterized protein. (489 aa)
SLC2A14MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (535 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
PRKCQProtein kinase C. (753 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (776 aa)
MAPK10Mitogen-activated protein kinase. (467 aa)
IRS2Insulin receptor substrate 2. (1316 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
PPARGC1APPARG coactivator 1 alpha. (793 aa)
SLC2A3MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (496 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (723 aa)
PPARAPeroxisome proliferator activated receptor alpha. (467 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
TRADDTNFRSF1A associated via death domain. (308 aa)
NFKBIENFKB inhibitor epsilon. (489 aa)
RXRBRetinoid X receptor beta. (533 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
AGRPAgouti related neuropeptide. (132 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
NFKB1Nuclear factor kappa B subunit 1. (977 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa)
ACSBG2Acyl-CoA synthetase bubblegum family member 2. (666 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (803 aa)
ACSL6AMP-binding domain-containing protein. (722 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (437 aa)
TNFRSF1BTNF receptor superfamily member 1B. (462 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (588 aa)
TNFRSF1ATNF receptor superfamily member 1A. (459 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (764 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (713 aa)
POMCProopiomelanocortin. (265 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
ADIPOR2Adiponectin receptor 2. (386 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (683 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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