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| | STAT5A | Signal transducer and activator of transcription. (794 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | NOX1 | NADPH oxidase 1. (564 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | NOX4 | NADPH oxidase 4. (584 aa) |
| | DIAPH1 | Diaphanous related formin 1. (1244 aa) |
| | F3 | Coagulation factor III, tissue factor. (296 aa) |
| | COL4A2 | Collagen type IV alpha 2 chain. (1712 aa) |
| | HRAS | Uncharacterized protein. (189 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | BCL2 | BCL2 apoptosis regulator. (238 aa) |
| | ENSPANP00000001773 | Uncharacterized protein. (189 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | LOC101024285 | Uncharacterized protein. (191 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | CYBB | Cytochrome b-245 beta chain. (570 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | COL4A1 | Collagen type IV alpha 1 chain. (1669 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (532 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (591 aa) |
| | COL4A5 | Collagen type IV alpha 5 chain. (1606 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | RAC1 | Rac family small GTPase 1. (211 aa) |
| | VEGFD | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa) |
| | COL3A1 | Collagen type III alpha 1 chain. (1466 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | PIK3R2 | Uncharacterized protein. (721 aa) |
| | XK | XK-related protein. (444 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | COL4A3 | Collagen type IV alpha 3 chain. (1670 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (490 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | FOXO1 | Forkhead box O1. (655 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (930 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (977 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | VEGFB | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (207 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) |
| | NOX3 | NADPH oxidase 3. (568 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (418 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | PIM1 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (402 aa) |
| | MMP2 | Matrix metallopeptidase 2. (660 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (412 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | EDN1 | Endothelin 1. (211 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1122 aa) |
| | COL1A2 | Collagen type I alpha 2 chain. (1366 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | COL4A4 | Collagen type IV alpha 4 chain. (1692 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1369 aa) |
| | PLCE1 | Phosphoinositide phospholipase C. (2317 aa) |
| | PLCD3 | Phosphoinositide phospholipase C. (785 aa) |
| | MFF | Mitochondrial fission factor. (342 aa) |
| | ENSPANP00000021931 | Uncharacterized protein. (175 aa) |
| | SERPINE1 | Serpin family E member 1; Belongs to the serpin family. (429 aa) |
| | ENSPANP00000022011 | Uncharacterized protein. (153 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) |
| | IL6 | Uncharacterized protein. (214 aa) |
| | VCAM1 | Vascular cell adhesion molecule 1. (739 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | SELE | Selectin E. (612 aa) |
| | AGTR1 | Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (394 aa) |
| | STAT1 | Signal transducer and activator of transcription. (791 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | ENSPANP00000032942 | Uncharacterized protein. (182 aa) |
| | PLCD4 | Phosphoinositide phospholipase C. (799 aa) |
| | PLCD1 | Phosphoinositide phospholipase C. (777 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1170 aa) |
| | COL4A6 | Collagen type IV alpha 6 chain. (1705 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (203 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (472 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | CCL2 | C-C motif chemokine. (99 aa) |
| | CDC42 | Cell division cycle 42. (191 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (467 aa) |
| | FN1 | Fibronectin 1. (2477 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (271 aa) |
| | STAT5B | Signal transducer and activator of transcription. (791 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (386 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (476 aa) |
| | ENSPANP00000045653 | CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (195 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | JAK2 | Tyrosine-protein kinase. (1133 aa) |
