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| | LOC101025045 | Ig-like domain-containing protein; Belongs to the MHC class I family. (435 aa) |
| | LOC101012738 | Ig-like domain-containing protein; Belongs to the MHC class I family. (365 aa) |
| | PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (701 aa) |
| | CDKN2B | Uncharacterized protein. (173 aa) |
| | LOC103887915 | Uncharacterized protein. (245 aa) |
| | ENSPANP00000022457 | Uncharacterized protein. (208 aa) |
| | TSC2 | TSC complex subunit 2. (1810 aa) |
| | GNA12 | G protein subunit alpha 12. (381 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa) |
| | PDIA3 | Protein disulfide-isomerase. (505 aa) |
| | GNAS | GNAS complex locus. (1037 aa) |
| | CALML4 | Calmodulin like 4. (194 aa) |
| | GNB5 | G protein subunit beta 5. (411 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (119 aa) |
| | HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (324 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (776 aa) |
| | GNG13 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | RAC2 | Rac family small GTPase 2. (192 aa) |
| | TRADD | TNFRSF1A associated via death domain. (308 aa) |
| | ROCK2 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (402 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (412 aa) |
| | GNAO1 | G protein subunit alpha o1. (354 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1095 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2680 aa) |
| | TAPBP | TAP binding protein. (503 aa) |
| | TAP1 | Transporter 1, ATP binding cassette subfamily B member. (808 aa) |
| | ATF6B | Activating transcription factor 6 beta. (711 aa) |
| | CALM3 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) |
| | STING1 | Stimulator of interferon protein. (379 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (977 aa) |
| | ELK1 | ETS domain-containing protein. (428 aa) |
| | PTGER1 | Prostaglandin E receptor 1. (402 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa) |
| | IFNB1 | Interferon beta 1. (187 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | SP1 | Sp1 transcription factor. (803 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | ENSPANP00000009247 | Uncharacterized protein. (583 aa) |
| | GNA11 | G protein subunit alpha 11. (359 aa) |
| | LOC103876580 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (930 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (459 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | LOC101025906 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | IRF3 | Interferon regulatory factor 3. (422 aa) |
| | RHEBL1 | RHEB like 1. (183 aa) |
| | PTGER4 | Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (461 aa) |
| | PIK3R2 | Uncharacterized protein. (721 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | ARHGEF11 | Rho guanine nucleotide exchange factor 11. (1550 aa) |
| | LOC101020237 | C-C motif chemokine. (92 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (520 aa) |
| | LOC101023471 | Uncharacterized protein. (189 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa) |
| | LOC101000991 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | RAC1 | Rac family small GTPase 1. (211 aa) |
| | FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (282 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | CASP3 | Caspase 3; Belongs to the peptidase C14A family. (277 aa) |
| | GNAI1 | G protein subunit alpha i1. (422 aa) |
| | IL10RA | Interleukin 10 receptor subunit alpha. (576 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (538 aa) |
| | PTRHD1 | Peptidyl-tRNA hydrolase domain containing 1. (140 aa) |
| | IL6R | Interleukin 6 receptor. (468 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | GNAI2 | G protein subunit alpha i2. (355 aa) |
| | CCR5 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (379 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (416 aa) |
| | C7orf31 | Chromosome 7 open reading frame 31. (590 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) |
| | ENSPANP00000001773 | Uncharacterized protein. (189 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa) |
| | E2F2 | E2F transcription factor 2. (438 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | CALR | Calreticulin. (417 aa) |
| | HRAS | Uncharacterized protein. (189 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (338 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa) |
| | RHOC | Ras homolog family member C. (193 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1517 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | CSDE1 | Cold shock domain containing E1. (844 aa) |
| | PPP3R1 | Uncharacterized protein. (189 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (916 aa) |
| | IL6 | Uncharacterized protein. (214 aa) |
| | RAC3 | Rac family small GTPase 3. (192 aa) |
| | GNG11 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | GNG14 | G protein subunit gamma 14. (94 aa) |
| | LOC101021633 | Ig-like domain-containing protein; Belongs to the MHC class I family. (366 aa) |
| | LOC101008579 | Cytochrome c. (105 aa) |
| | ENSPANP00000025070 | SCY domain-containing protein. (77 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (569 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa) |
| | ENSPANP00000026330 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (519 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa) |
| | ENSPANP00000027932 | MHC_I-like_Ag-recog domain-containing protein. (213 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1075 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | LOC101008637 | MHC_I-like_Ag-recog domain-containing protein. (170 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | CALM2 | Calmodulin 2. (149 aa) |
| | ENSPANP00000028312 | Ig-like domain-containing protein; Belongs to the MHC class I family. (401 aa) |
| | ENSPANP00000029069 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (95 aa) |
| | SRC | Tyrosine-protein kinase. (644 aa) |
| | ENSPANP00000029353 | MHC_I-like_Ag-recog domain-containing protein. (152 aa) |
| | ENSPANP00000029629 | ETS domain-containing protein. (384 aa) |
| | ENSPANP00000030371 | Uncharacterized protein; Belongs to the calmodulin family. (128 aa) |
| | ENSPANP00000030750 | Uncharacterized protein. (166 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | LOC101003176 | C-C motif chemokine. (92 aa) |
| | LOC101007932 | MHC class I antigen; Belongs to the MHC class I family. (365 aa) |
| | AKAP13 | A-kinase anchoring protein 13. (2875 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | ENSPANP00000032024 | Ig-like domain-containing protein; Belongs to the MHC class I family. (370 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | ARHGEF1 | Rho guanine nucleotide exchange factor 1. (998 aa) |
| | E2F3 | E2F transcription factor 3. (460 aa) |
| | ENSPANP00000033457 | Uncharacterized protein; Belongs to the calmodulin family. (99 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa) |
| | LOC101017275 | C-C motif chemokine. (66 aa) |
| | CALML6 | Calmodulin like 6. (181 aa) |
| | TAP2 | Transporter 2, ATP binding cassette subfamily B member. (703 aa) |
| | ENSPANP00000034786 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (63 aa) |
| | LOC101002482 | Ig-like domain-containing protein; Belongs to the MHC class I family. (404 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1170 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (788 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | LOC101019008 | Uncharacterized protein. (198 aa) |
| | PACA-F | Ig-like domain-containing protein; Belongs to the MHC class I family. (430 aa) |
| | LOC101019879 | SCY domain-containing protein. (93 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (203 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | ENSPANP00000037790 | Ig-like domain-containing protein; Belongs to the MHC class I family. (365 aa) |
| | CCL2 | C-C motif chemokine. (99 aa) |
| | ENSPANP00000038680 | MHC_I-like_Ag-recog domain-containing protein. (137 aa) |
| | ADCY6 | Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (385 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (933 aa) |
| | PXN | Paxillin. (1082 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (776 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | ENSPANP00000039524 | IGc1 domain-containing protein; Belongs to the MHC class I family. (339 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (925 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | IFNA6 | Interferon alpha 6. (190 aa) |
| | ENSPANP00000040203 | Ig-like domain-containing protein; Belongs to the MHC class I family. (357 aa) |
| | GNG2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa) |
| | ENSPANP00000041348 | Uncharacterized protein. (182 aa) |
| | CREB3L4 | cAMP responsive element binding protein 3 like 4. (422 aa) |
| | ADCY5 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1255 aa) |
| | LOC101015730 | MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (260 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | ENSPANP00000042342 | Ig-like domain-containing protein; Belongs to the MHC class I family. (397 aa) |
| | RAF1 | Uncharacterized protein. (668 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (386 aa) |
| | ENSPANP00000043062 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1096 aa) |
| | LOC100997529 | Cytochrome c. (105 aa) |
| | PVALEF | Parvalbumin like EF-hand containing. (133 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | LOC101001771 | C-C motif chemokine. (71 aa) |
| | ENSPANP00000044663 | Ig-like domain-containing protein; Belongs to the MHC class I family. (348 aa) |
| | CXCR2 | C-X-C motif chemokine receptor 2. (328 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (476 aa) |
| | ENSPANP00000045653 | CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (195 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2723 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | LOC100997503 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa) |
| | LOC101021327 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | RUFY4 | RUN and FYVE domain containing 4. (586 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | LOC100997246 | Ig-like domain-containing protein; Belongs to the MHC class I family. (375 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa) |
| | LOC101018109 | C-C motif chemokine 4-like. (92 aa) |
| | ENSPANP00000047699 | G protein gamma domain-containing protein. (63 aa) |
| | ENSPANP00000021624 | BZIP domain-containing protein. (322 aa) |
| | PTGER3 | Prostaglandin E receptor 3. (415 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (303 aa) |
| | CGAS | Mab-21 domain-containing protein. (522 aa) |
| | CXCR4 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (355 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | GNA13 | G protein subunit alpha 13. (377 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | E2F1 | E2F transcription factor 1. (423 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa) |
| | PTGER2 | Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1122 aa) |
| | BID | BH3 interacting domain death agonist. (244 aa) |
| | LOC100510871 | C-C motif chemokine. (79 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa) |
| | ENSPANP00000017487 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | LOC101015220 | MHC class I protein; Belongs to the MHC class I family. (365 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1. (118 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa) |
| | GNGT1 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | RB1 | RB transcriptional corepressor 1. (889 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (497 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (184 aa) |
| | IL10RB | Interleukin 10 receptor, beta (Predicted). (325 aa) |
| | GNB2 | G protein subunit beta 2. (340 aa) |
| | TSC1 | TSC complex subunit 1. (1168 aa) |
| | GNG10 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (372 aa) |
| | GNAQ | G protein subunit alpha q. (384 aa) |
| | CRK | CRK proto-oncogene, adaptor protein. (304 aa) |
| | LOC100999050 | C-C motif chemokine. (92 aa) |
| | CCL4 | C-C motif chemokine. (92 aa) |
| | CALM1 | Calmodulin 1. (149 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa) |
| | FAS | Fas cell surface death receptor. (342 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | CCR3 | C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa) |
