STRINGSTRING
STAT3 STAT3 CSDE1 CSDE1 CCND1 CCND1 BAD BAD HRAS HRAS PIK3R1 PIK3R1 IL3 IL3 ENSPANP00000001773 ENSPANP00000001773 PPP1R14B PPP1R14B PIK3R3 PIK3R3 AKT3 AKT3 PER2 PER2 CSF2 CSF2 TCF7L1 TCF7L1 ARAF ARAF PIK3CA PIK3CA PIM2 PIM2 LOC101003793 LOC101003793 CEBPA CEBPA PIK3R2 PIK3R2 SPI1 SPI1 ENSPANP00000007612 ENSPANP00000007612 DUSP6 DUSP6 RPS6KB2 RPS6KB2 MYC MYC ENSPANP00000009247 ENSPANP00000009247 ZBTB16 ZBTB16 CSF1R CSF1R NFKB1 NFKB1 NRAS NRAS CCNA1 CCNA1 PPARD PPARD MAPK3 MAPK3 PIM1 PIM1 ITGAM ITGAM AKT1 AKT1 PML PML BCL2A1 BCL2A1 PIK3CD PIK3CD CCNA2 CCNA2 MTOR MTOR GRB2 GRB2 SOS2 SOS2 SOS1 SOS1 EIF4EBP1 EIF4EBP1 ERAS ERAS KIT KIT BRAF BRAF MPO MPO JUP JUP CHUK CHUK TCF7 TCF7 MAP2K1 MAP2K1 ENSPANP00000024582 ENSPANP00000024582 ENSPANP00000024626 ENSPANP00000024626 RUNX1 RUNX1 MAPK1 MAPK1 STAT5A STAT5A RPS6KB1 RPS6KB1 TCF7L2 TCF7L2 CD14 CD14 FLT3 FLT3 PIK3CB PIK3CB LEF1 LEF1 RUNX1T1 RUNX1T1 MAP2K2 MAP2K2 IKBKB IKBKB RAF1 RAF1 STAT5B STAT5B RARA RARA RELA RELA AKT2 AKT2 CEBPE CEBPE KRAS KRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STAT3Signal transducer and activator of transcription. (770 aa)
CSDE1Cold shock domain containing E1. (844 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
BADBCL2 associated agonist of cell death. (168 aa)
HRASUncharacterized protein. (189 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
IL3Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (151 aa)
ENSPANP00000001773Uncharacterized protein. (189 aa)
PPP1R14BUncharacterized protein. (207 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PER2Period circadian regulator 2. (1280 aa)
CSF2Granulocyte-macrophage colony-stimulating factor (Predicted). (144 aa)
TCF7L1Transcription factor 7 like 1. (589 aa)
ARAFA-Raf proto-oncogene, serine/threonine kinase. (606 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (311 aa)
LOC101003793Uncharacterized protein. (357 aa)
CEBPACCAAT/enhancer-binding protein. (349 aa)
PIK3R2Uncharacterized protein. (721 aa)
SPI1Spi-1 proto-oncogene. (271 aa)
ENSPANP00000007612Uncharacterized protein. (190 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
ENSPANP00000009247Uncharacterized protein. (583 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (975 aa)
NFKB1Nuclear factor kappa B subunit 1. (977 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (402 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PMLPromyelocytic leukemia. (882 aa)
BCL2A1BCL2 related protein A1. (175 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1332 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
ERASES cell expressed Ras. (233 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (763 aa)
MPOMyeloperoxidase. (745 aa)
JUPJunction plakoglobin. (745 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
TCF7Transcription factor 7. (480 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ENSPANP00000024582Uncharacterized protein. (147 aa)
ENSPANP00000024626Uncharacterized protein. (82 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
TCF7L2Transcription factor 7 like 2. (529 aa)
CD14CD14 molecule. (384 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (995 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
LEF1Lymphoid enhancer binding factor 1. (414 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (662 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (385 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (776 aa)
RAF1Uncharacterized protein. (668 aa)
STAT5BSignal transducer and activator of transcription. (791 aa)
RARARetinoic acid receptor alpha. (478 aa)
RELARELA proto-oncogene, NF-kB subunit. (476 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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