STRINGSTRING
MCOLN1 MCOLN1 TRPM2 TRPM2 ORAI2 ORAI2 TRPM8 TRPM8 STIM2 STIM2 CACNA1H CACNA1H MCOLN2 MCOLN2 TRPC5 TRPC5 TRPM5 TRPM5 TRPC4 TRPC4 TRPC7 TRPC7 STIM1 STIM1 TRPC3 TRPC3 ORAI1 ORAI1 TRPV1 TRPV1 TRPV3 TRPV3 CALM2 CALM2 TRPM7 TRPM7 MCOLN3 MCOLN3 LOC105549269 LOC105549269 CACNA1G CACNA1G TRPV2 TRPV2 TRPV4 TRPV4 ORAI3 ORAI3 TRPA1 TRPA1 TRPV5 TRPV5 TRPC6 TRPC6 CACNA1I CACNA1I ENSMLEP00000030524 ENSMLEP00000030524 TRPC1 TRPC1 TRPM3 TRPM3 PRKCH PRKCH PIEZO2 PIEZO2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCOLN1Mucolipin 1. (553 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1552 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (254 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
STIM2Stromal interaction molecule 2. (724 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2170 aa)
MCOLN2Mucolipin 2. (566 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
TRPM5Transient receptor potential cation channel subfamily M member 5. (1081 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (863 aa)
STIM1Stromal interaction molecule 1. (790 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (849 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (238 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (850 aa)
TRPV3Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
CALM2Calmodulin 2. (149 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1846 aa)
MCOLN3Mucolipin 3. (553 aa)
LOC105549269TRP_2 domain-containing protein. (780 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2360 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
ORAI3ORAI calcium release-activated calcium modulator 3. (295 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (729 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2080 aa)
ENSMLEP00000030524XRCC1_N domain-containing protein. (142 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (809 aa)
TRPM3Transient receptor potential cation channel subfamily M member 3. (1711 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
PIEZO2Piezo-type mechanosensitive ion channel component. (2778 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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