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CHRM5 CHRM5 GPR12 GPR12 APLNR APLNR GNA11 GNA11 CHRM2 CHRM2 KCNJ6 KCNJ6 SLC6A4 SLC6A4 ENSMLEP00000001951 ENSMLEP00000001951 CHRM4 CHRM4 TAS2R38 TAS2R38 HTR1B HTR1B GNB4 GNB4 GNAS GNAS CHRM1 CHRM1 HTR2B HTR2B HTR1D HTR1D GNAI2 GNAI2 LPAR4 LPAR4 GNB3 GNB3 LPAR6 LPAR6 GPR55 GPR55 HRH1 HRH1 ENSMLEP00000007417 ENSMLEP00000007417 HTR1F HTR1F LOC105535118 LOC105535118 HTR2A HTR2A CYSLTR1 CYSLTR1 HTR1A HTR1A CASR CASR GNG2 GNG2 GRM3 GRM3 LOC105550079 LOC105550079 TAS1R1 TAS1R1 ADORA2A ADORA2A PLCB4 PLCB4 GNAQ GNAQ TAS1R3 TAS1R3 DRD3 DRD3 GPSM1 GPSM1 PTGER4 PTGER4 HTR7 HTR7 GNAT3 GNAT3 GNA14 GNA14 PRKCE PRKCE PTGER2 PTGER2 GPRC6A GPRC6A KCNJ9 KCNJ9 GNA15 GNA15 F2R F2R HTR1E HTR1E GNB1 GNB1 HTR2C HTR2C PTGER3 PTGER3 GABBR1 GABBR1 ADRA1D ADRA1D PLCB2 PLCB2 LOC105542086 LOC105542086 GNB2 GNB2 KCNJ3 KCNJ3 GNGT2 GNGT2 GNAI3 GNAI3 ADRA1B ADRA1B ZFX ZFX ENSMLEP00000028401 ENSMLEP00000028401 ADORA2B ADORA2B GNAO1 GNAO1 GNG12 GNG12 PREX1 PREX1 LPAR2 LPAR2 GNG5 GNG5 GNG3 GNG3 GNG4 GNG4 HTR5A HTR5A TBXA2R TBXA2R GNGT1 GNGT1 GNAI1 GNAI1 GNG8 GNG8 TAS1R2 TAS1R2 KCNJ5 KCNJ5 GRM5 GRM5 GNG13 GNG13 ADRA1A ADRA1A PTGER1 PTGER1 PLCB3 PLCB3 LPAR1 LPAR1 LPAR3 LPAR3 GABBR2 GABBR2 DRD2 DRD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHRM5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
GPR12G protein-coupled receptor 12; Belongs to the G-protein coupled receptor 1 family. (334 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
GNA11G protein subunit alpha 11. (307 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
ENSMLEP00000001951Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (60 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (479 aa)
TAS2R38Taste receptor type 2. (333 aa)
HTR1B5-hydroxytryptamine receptor 1B. (390 aa)
GNB4G protein subunit beta 4. (340 aa)
GNASGNAS complex locus. (998 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
HTR1D5-hydroxytryptamine receptor 1D. (377 aa)
GNAI2G protein subunit alpha i2. (352 aa)
LPAR4Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (370 aa)
GNB3G protein subunit beta 3. (340 aa)
LPAR6Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family. (344 aa)
GPR55G protein-coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (319 aa)
HRH1Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (487 aa)
ENSMLEP00000007417Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
HTR1F5-hydroxytryptamine receptor 1F. (366 aa)
LOC105535118Taste receptor type 2. (309 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
CYSLTR1Cysteinyl leukotriene receptor 1. (337 aa)
HTR1A5-hydroxytryptamine receptor 1A. (422 aa)
CASRCalcium sensing receptor. (1088 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
GRM3Glutamate metabotropic receptor 3. (879 aa)
LOC105550079Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
TAS1R1Taste 1 receptor member 1. (841 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1165 aa)
GNAQG protein subunit alpha q. (313 aa)
TAS1R3Taste 1 receptor member 3. (852 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
GPSM1G protein signaling modulator 1. (652 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (470 aa)
HTR75-hydroxytryptamine receptor 7. (432 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
GNA14G protein subunit alpha 14. (355 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
PTGER2Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
GPRC6AG protein-coupled receptor class C group 6 member A. (928 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (411 aa)
GNA15G protein subunit alpha 15. (374 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
HTR1E5-hydroxytryptamine receptor 1E. (362 aa)
GNB1G protein subunit beta 1. (340 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
PTGER3Prostaglandin E receptor 3. (415 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (966 aa)
ADRA1DAdrenoceptor alpha 1D; Belongs to the G-protein coupled receptor 1 family. (307 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1089 aa)
LOC105542086G_PROTEIN_RECEP_F1_2 domain-containing protein. (372 aa)
GNB2G protein subunit beta 2. (340 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
GNAI3G protein subunit alpha i3. (354 aa)
ADRA1BAdrenoceptor alpha 1B. (458 aa)
ZFXZinc finger protein X-linked. (841 aa)
ENSMLEP00000028401Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
GNAO1G protein subunit alpha o1. (354 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1654 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
HTR5A5-hydroxytryptamine receptor 5A. (357 aa)
TBXA2RThromboxane A2 receptor. (329 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNAI1G protein subunit alpha i1. (314 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
TAS1R2Taste 1 receptor member 2. (839 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (419 aa)
GRM5Glutamate metabotropic receptor 5. (1039 aa)
GNG13Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
PTGER1Prostaglandin E receptor 1. (402 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1245 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (366 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (353 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (890 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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