node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHRM1 | CHRM5 | ENSMLEP00000005215 | ENSMLEP00000000085 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | 0.986 |
CHRM1 | GNA11 | ENSMLEP00000005215 | ENSMLEP00000001230 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit alpha 11. | 0.909 |
CHRM1 | GNA14 | ENSMLEP00000005215 | ENSMLEP00000015106 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit alpha 14. | 0.792 |
CHRM1 | GNA15 | ENSMLEP00000005215 | ENSMLEP00000019346 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit alpha 15. | 0.786 |
CHRM1 | GNAQ | ENSMLEP00000005215 | ENSMLEP00000009684 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit alpha q. | 0.913 |
CHRM1 | GRM5 | ENSMLEP00000005215 | ENSMLEP00000036981 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | Glutamate metabotropic receptor 5. | 0.904 |
CHRM1 | PLCB3 | ENSMLEP00000005215 | ENSMLEP00000039046 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.542 |
CHRM5 | CHRM1 | ENSMLEP00000000085 | ENSMLEP00000005215 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | 0.986 |
CHRM5 | GNA11 | ENSMLEP00000000085 | ENSMLEP00000001230 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit alpha 11. | 0.988 |
CHRM5 | GNA14 | ENSMLEP00000000085 | ENSMLEP00000015106 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit alpha 14. | 0.640 |
CHRM5 | GNA15 | ENSMLEP00000000085 | ENSMLEP00000019346 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit alpha 15. | 0.711 |
CHRM5 | GNAQ | ENSMLEP00000000085 | ENSMLEP00000009684 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | G protein subunit alpha q. | 0.818 |
CHRM5 | GRM5 | ENSMLEP00000000085 | ENSMLEP00000036981 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | Glutamate metabotropic receptor 5. | 0.986 |
CHRM5 | PLCB3 | ENSMLEP00000000085 | ENSMLEP00000039046 | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.413 |
GNA11 | CHRM1 | ENSMLEP00000001230 | ENSMLEP00000005215 | G protein subunit alpha 11. | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | 0.909 |
GNA11 | CHRM5 | ENSMLEP00000001230 | ENSMLEP00000000085 | G protein subunit alpha 11. | Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. | 0.988 |
GNA11 | GNA15 | ENSMLEP00000001230 | ENSMLEP00000019346 | G protein subunit alpha 11. | G protein subunit alpha 15. | 0.572 |
GNA11 | GNAQ | ENSMLEP00000001230 | ENSMLEP00000009684 | G protein subunit alpha 11. | G protein subunit alpha q. | 0.895 |
GNA11 | GRM5 | ENSMLEP00000001230 | ENSMLEP00000036981 | G protein subunit alpha 11. | Glutamate metabotropic receptor 5. | 0.914 |
GNA11 | HRH1 | ENSMLEP00000001230 | ENSMLEP00000007339 | G protein subunit alpha 11. | Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. | 0.893 |