STRINGSTRING
NUF2 NUF2 HMMR HMMR PARPBP PARPBP LOC105552712 LOC105552712 LOC105540905 LOC105540905 AURKA AURKA CDK2 CDK2 ANAPC2 ANAPC2 KIF23 KIF23 NCAPH NCAPH LOC105554486 LOC105554486 LOC105542819 LOC105542819 BUB1B BUB1B CCNI2 CCNI2 TACC3 TACC3 BATF3 BATF3 NCAPD3 NCAPD3 ENSMLEP00000003186 ENSMLEP00000003186 LOC105530754 LOC105530754 ZCWPW2 ZCWPW2 ESPL1 ESPL1 KIF17 KIF17 DSN1 DSN1 MELK MELK ZNF207 ZNF207 KIF14 KIF14 WEE2 WEE2 PCLAF PCLAF MIS12 MIS12 LOC105539644 LOC105539644 BUB1 BUB1 SPDL1 SPDL1 SOWAHB SOWAHB SKA2 SKA2 KNSTRN KNSTRN CDK3 CDK3 SKA3 SKA3 ASPM ASPM DLGAP5 DLGAP5 ANAPC5 ANAPC5 LOC105534136 LOC105534136 ANAPC13 ANAPC13 CKAP2L CKAP2L NSL1 NSL1 KIF4A KIF4A CENPE CENPE MAD2L1BP MAD2L1BP ZCWPW1 ZCWPW1 NCAPG2 NCAPG2 CCNB1 CCNB1 CHEK2 CHEK2 AURKC AURKC KNTC1 KNTC1 NCAPD2 NCAPD2 CDKN1B CDKN1B CIT CIT CEP55 CEP55 CDKN1A CDKN1A ARHGAP11A ARHGAP11A CKS1B CKS1B MAD1L1 MAD1L1 KIF18A KIF18A SKA1 SKA1 TTK TTK KIFC1 KIFC1 FBXO43 FBXO43 CDK17 CDK17 SMC4 SMC4 ECT2 ECT2 BUB3 BUB3 CCNE2 CCNE2 FBXO5 FBXO5 CDK16 CDK16 LOC105530751 LOC105530751 CDCA5 CDCA5 PBK PBK SPC24 SPC24 ANAPC11 ANAPC11 FAM83D FAM83D ZWILCH ZWILCH ANLN ANLN KIF20A KIF20A UBE2C UBE2C ENSMLEP00000015919 ENSMLEP00000015919 NCAPH2 NCAPH2 PMF1-BGLAP PMF1-BGLAP ENSMLEP00000017044 ENSMLEP00000017044 CCNB2 CCNB2 CHEK1 CHEK1 KIFC3 KIFC3 BATF BATF CDKN2A CDKN2A CDCA8 CDCA8 CCNF CCNF ENSMLEP00000018790 ENSMLEP00000018790 CCND3 CCND3 SPAG5 SPAG5 CDCA3 CDCA3 NDC80 NDC80 KIFC2 KIFC2 PTTG2 PTTG2 TPX2 TPX2 BIRC5 BIRC5 CCNG2 CCNG2 KIF20B KIF20B ANAPC16 ANAPC16 UHRF1 UHRF1 PRC1 PRC1 SMC2 SMC2 CDC27 CDC27 PLK1 PLK1 LOC105532146 LOC105532146 CKS2 CKS2 TROAP TROAP CDC25C CDC25C TRIP13 TRIP13 KIF15 KIF15 SKP2 SKP2 ENSMLEP00000024146 ENSMLEP00000024146 PTTG1 PTTG1 CDKN3 CDKN3 LOC105530484 LOC105530484 MAD2L1 MAD2L1 ENSMLEP00000025412 ENSMLEP00000025412 CDK6 CDK6 CENPF CENPF LOC105531290 LOC105531290 FOXM1 FOXM1 CDK4 CDK4 ANAPC1 ANAPC1 CDKN2B CDKN2B ZWINT ZWINT CNTD2 CNTD2 CDC20 CDC20 ENSMLEP00000027534 ENSMLEP00000027534 CCNA1 CCNA1 ANAPC7 ANAPC7 SPC25 SPC25 CCNG1 CCNG1 CDC20B CDC20B CENPA CENPA CDKN2C CDKN2C ANAPC4 ANAPC4 AURKB AURKB CCNE1 CCNE1 ENSMLEP00000031583 ENSMLEP00000031583 RACGAP1 RACGAP1 E2F7 E2F7 HJURP HJURP ENSMLEP00000033047 ENSMLEP00000033047 TOP2A TOP2A KIF11 KIF11 CCND2 CCND2 ANAPC10 ANAPC10 CDC16 CDC16 CCNA2 CCNA2 ENSMLEP00000034485 ENSMLEP00000034485 CDCA2 CDCA2 KIF18B KIF18B CDC25A CDC25A FZR1 FZR1 NCAPG NCAPG CIP2A CIP2A KIF2C KIF2C ENSMLEP00000036889 ENSMLEP00000036889 NEK2 NEK2 KIF22 KIF22 E2F8 E2F8 C1orf112 C1orf112 ENSMLEP00000038171 ENSMLEP00000038171 UBE2S UBE2S CDK1 CDK1 CKAP2 CKAP2 INCENP INCENP CCNB3 CCNB3 LOC105537660 LOC105537660 ANAPC15 ANAPC15 NUSAP1 NUSAP1 ENSMLEP00000040613 ENSMLEP00000040613 BATF2 BATF2 CDC26 CDC26 CUL1 CUL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NUF2NUF2 component of NDC80 kinetochore complex. (464 aa)
HMMRHyaluronan mediated motility receptor. (707 aa)
PARPBPPARP1 binding protein. (625 aa)
LOC105552712UBIQUITIN_CONJUGAT_2 domain-containing protein. (179 aa)
LOC10554090514_3_3 domain-containing protein; Belongs to the 14-3-3 family. (248 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (384 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (822 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (960 aa)
NCAPHCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (678 aa)
LOC105554486Uncharacterized protein. (200 aa)
LOC105542819UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
BUB1BBUB1 N-terminal domain-containing protein. (1050 aa)
CCNI2Cyclin I family member 2; Belongs to the cyclin family. (261 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (817 aa)
BATF3Basic leucine zipper ATF-like transcription factor 3. (97 aa)
NCAPD3Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. (1497 aa)
ENSMLEP00000003186Uncharacterized protein. (143 aa)
LOC105530754Uncharacterized protein. (302 aa)
ZCWPW2Zinc finger CW-type and PWWP domain containing 2. (362 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2100 aa)
KIF17Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (951 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (354 aa)
MELKNon-specific serine/threonine protein kinase. (651 aa)
ZNF207Zinc finger protein 207. (497 aa)
KIF14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1649 aa)
WEE2Wee1-like protein kinase. (568 aa)
PCLAFPAF domain-containing protein. (115 aa)
MIS12Uncharacterized protein. (205 aa)
LOC105539644WD_REPEATS_REGION domain-containing protein. (649 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1096 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (605 aa)
SOWAHBSosondowah ankyrin repeat domain family member B. (793 aa)
SKA2SKA2 domain-containing protein. (121 aa)
KNSTRNKinetochore localized astrin (SPAG5) binding protein. (261 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
SKA3Spindle and kinetochore associated complex subunit 3. (412 aa)
ASPMAbnormal spindle microtubule assembly. (3476 aa)
DLGAP5DLG associated protein 5. (851 aa)
ANAPC5Anaphase promoting complex subunit 5. (755 aa)
LOC105534136UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
ANAPC13Anaphase promoting complex subunit 13. (74 aa)
CKAP2LCytoskeleton associated protein 2 like. (742 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (190 aa)
KIF4AKinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1227 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2700 aa)
MAD2L1BPMAD2L1 binding protein. (306 aa)
ZCWPW1Zinc finger CW-type and PWWP domain containing 1. (643 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1143 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (433 aa)
CHEK2Checkpoint kinase 2. (558 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
KNTC1Kinetochore associated 1. (2187 aa)
NCAPD2Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1399 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2003 aa)
CEP55Centrosomal protein 55. (458 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
ARHGAP11ARho GTPase activating protein 11A. (1023 aa)
CKS1BCyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (407 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (533 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)
TTKTTK protein kinase. (855 aa)
KIFC1Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (728 aa)
FBXO43F-box protein 43. (679 aa)
CDK17Cyclin dependent kinase 17. (523 aa)
SMC4Structural maintenance of chromosomes protein. (1287 aa)
ECT2Epithelial cell transforming 2. (917 aa)
BUB3WD_REPEATS_REGION domain-containing protein. (328 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (404 aa)
FBXO5F-box protein 5. (448 aa)
CDK16Cyclin dependent kinase 16. (570 aa)
LOC105530751Uncharacterized protein. (302 aa)
CDCA5Cell division cycle associated 5. (252 aa)
PBKPDZ binding kinase. (334 aa)
SPC24SPC24 component of NDC80 kinetochore complex. (205 aa)
ANAPC11Anaphase promoting complex subunit 11. (165 aa)
FAM83DFamily with sequence similarity 83 member D. (500 aa)
ZWILCHZwilch kinetochore protein. (568 aa)
ANLNAnillin actin binding protein. (1127 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (890 aa)
UBE2CUncharacterized protein. (161 aa)
ENSMLEP00000015919DOC domain-containing protein. (126 aa)
NCAPH2Non-SMC condensin II complex subunit H2. (596 aa)
PMF1-BGLAPPMF1-BGLAP readthrough. (171 aa)
ENSMLEP00000017044Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (86 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (398 aa)
CHEK1Checkpoint kinase 1. (480 aa)
KIFC3Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (849 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (159 aa)
CDCA8Cell division cycle associated 8. (280 aa)
CCNFCyclin F; Belongs to the cyclin family. (786 aa)
ENSMLEP00000018790Uncharacterized protein. (416 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (242 aa)
SPAG5Sperm associated antigen 5. (1162 aa)
CDCA3Cell division cycle associated 3. (268 aa)
NDC80NDC80 kinetochore complex component. (642 aa)
KIFC2Kinesin family member C2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (526 aa)
PTTG2Pituitary tumor-transforming 2. (169 aa)
TPX2TPX2 microtubule nucleation factor. (782 aa)
BIRC5Uncharacterized protein. (147 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (344 aa)
KIF20BKinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1823 aa)
ANAPC16Anaphase promoting complex subunit 16. (110 aa)
UHRF1Ubiquitin like with PHD and ring finger domains 1. (796 aa)
PRC1Protein regulator of cytokinesis 1. (624 aa)
SMC2Structural maintenance of chromosomes protein. (1178 aa)
CDC27Cell division cycle 27. (834 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
LOC105532146Uncharacterized protein. (434 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
TROAPTrophinin associated protein. (777 aa)
CDC25CCell division cycle 25C. (474 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (407 aa)
KIF15Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1388 aa)
SKP2S-phase kinase associated protein 2. (424 aa)
ENSMLEP00000024146Uncharacterized protein. (136 aa)
PTTG1PTTG1 regulator of sister chromatid separation, securin. (202 aa)
CDKN3Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (211 aa)
LOC105530484Uncharacterized protein. (306 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
ENSMLEP00000025412Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (69 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
CENPFCentromere protein F. (3113 aa)
LOC105531290TPR_REGION domain-containing protein. (274 aa)
FOXM1Forkhead box M1. (770 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
ANAPC1Anaphase promoting complex subunit 1. (1936 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (157 aa)
ZWINTZW10 interacting kinetochore protein. (277 aa)
CNTD2Cyclin N-terminal domain containing 2; Belongs to the cyclin family. (198 aa)
CDC20Cell division cycle 20. (499 aa)
ENSMLEP00000027534ANAPC8 domain-containing protein. (151 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
ANAPC7Anaphase promoting complex subunit 7. (599 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (224 aa)
CCNG1Cyclin G1; Belongs to the cyclin family. (295 aa)
CDC20BCell division cycle 20B. (477 aa)
CENPACentromere protein A. (138 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (793 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (345 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (407 aa)
ENSMLEP00000031583UBIQUITIN_CONJUGAT_2 domain-containing protein. (149 aa)
RACGAP1Rac GTPase activating protein 1. (632 aa)
E2F7E2F transcription factor 7. (910 aa)
HJURPHolliday junction recognition protein. (736 aa)
ENSMLEP00000033047Uncharacterized protein. (67 aa)
TOP2ADNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa)
KIF11Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1056 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
CDC16Cell division cycle 16. (606 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
ENSMLEP00000034485Uncharacterized protein. (87 aa)
CDCA2Cell division cycle associated 2. (1024 aa)
KIF18BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (853 aa)
CDC25ACell division cycle 25A. (524 aa)
FZR1Fizzy and cell division cycle 20 related 1. (522 aa)
NCAPGNon-SMC condensin I complex subunit G. (1044 aa)
CIP2ACell proliferation regulating inhibitor of protein phosphatase 2A. (852 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (725 aa)
ENSMLEP00000036889Uncharacterized protein. (182 aa)
NEK2NIMA related kinase 2. (445 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (657 aa)
E2F8E2F transcription factor 8. (867 aa)
C1orf112Chromosome 1 open reading frame 112. (854 aa)
ENSMLEP00000038171Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (66 aa)
UBE2SUncharacterized protein. (79 aa)
CDK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
CKAP2Cytoskeleton associated protein 2. (683 aa)
INCENPInner centromere protein. (897 aa)
CCNB3Cyclin B3; Belongs to the cyclin family. (1365 aa)
LOC105537660Uncharacterized protein. (140 aa)
ANAPC15Anaphase promoting complex subunit 15. (190 aa)
NUSAP1Uncharacterized protein. (380 aa)
ENSMLEP00000040613Protein kinase domain-containing protein. (286 aa)
BATF2Basic leucine zipper ATF-like transcription factor 2. (273 aa)
CDC26Cell division cycle 26. (85 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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