STRINGSTRING
RPS27A RPS27A UBE2NL UBE2NL UBE2L5 UBE2L5 UBE2U UBE2U RAD18 RAD18 LOC105541098 LOC105541098 LOC105534329 LOC105534329 ENSMLEP00000005424 ENSMLEP00000005424 UBE2L6 UBE2L6 ENSMLEP00000006240 ENSMLEP00000006240 LOC105537674 LOC105537674 LOC105540679 LOC105540679 LOC105536598 LOC105536598 LOC105535829 LOC105535829 RNF168 RNF168 LOC105549649 LOC105549649 HLTF HLTF UBE2K UBE2K MIB2 MIB2 ZFAND4 ZFAND4 ENSMLEP00000011388 ENSMLEP00000011388 UBD UBD LOC105532611 LOC105532611 UBE2G1 UBE2G1 SHPRH SHPRH UBE2R2 UBE2R2 LOC105532189 LOC105532189 ENSMLEP00000018394 ENSMLEP00000018394 UBE2V2 UBE2V2 UBE2J1 UBE2J1 UBE2O UBE2O TRAF7 TRAF7 UBE2D1 UBE2D1 ENSMLEP00000024034 ENSMLEP00000024034 ENSMLEP00000024603 ENSMLEP00000024603 PIAS4 PIAS4 UBE2D3 UBE2D3 STUB1 STUB1 UBA7 UBA7 UBE2J2 UBE2J2 RNF4 RNF4 UBE2W UBE2W UBA6 UBA6 UBA52 UBA52 UBA1 UBA1 UBE2D4 UBE2D4 CDC34 CDC34 UBE2H UBE2H ENSMLEP00000034242 ENSMLEP00000034242 ARIH1 ARIH1 UBOX5 UBOX5 UBE2Z UBE2Z RNF8 RNF8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS27AUbiquitin-like domain-containing protein. (138 aa)
UBE2NLUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
UBE2L5Ubiquitin conjugating enzyme E2 L5; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
UBE2UUbiquitin conjugating enzyme E2 U; Belongs to the ubiquitin-conjugating enzyme family. (226 aa)
RAD18RAD18 E3 ubiquitin protein ligase. (496 aa)
LOC105541098Ubiquitin-like domain-containing protein. (156 aa)
LOC105534329UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
ENSMLEP00000005424UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
UBE2L6Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (160 aa)
ENSMLEP00000006240Ubiquitin-like domain-containing protein. (127 aa)
LOC105537674UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
LOC105540679UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
LOC105536598Ubiquitin-like domain-containing protein. (156 aa)
LOC105535829Ubiquitin-like domain-containing protein. (207 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (565 aa)
LOC105549649UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (146 aa)
HLTFHelicase like transcription factor. (1009 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
MIB2Mindbomb E3 ubiquitin protein ligase 2. (669 aa)
ZFAND4Zinc finger AN1-type containing 4. (534 aa)
ENSMLEP00000011388Ubiquitin-like domain-containing protein. (120 aa)
UBDUbiquitin D. (165 aa)
LOC105532611UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (140 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (187 aa)
SHPRHSNF2 histone linker PHD RING helicase. (1683 aa)
UBE2R2Ubiquitin conjugating enzyme E2 R2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
LOC105532189Uncharacterized protein. (151 aa)
ENSMLEP00000018394UBIQUITIN_CONJUGAT_2 domain-containing protein. (129 aa)
UBE2V2Ubiquitin conjugating enzyme E2 V2. (155 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (313 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1099 aa)
TRAF7TNF receptor associated factor 7. (670 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
ENSMLEP00000024034UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
ENSMLEP00000024603UBIQUITIN_CONJUGAT_2 domain-containing protein. (102 aa)
PIAS4Protein inhibitor of activated STAT 4. (510 aa)
UBE2D3UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
STUB1STIP1 homology and U-box containing protein 1. (250 aa)
UBA7Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1013 aa)
UBE2J2Ubiquitin conjugating enzyme E2 J2. (179 aa)
RNF4Ring finger protein 4. (190 aa)
UBE2WUBIQUITIN_CONJUGAT_2 domain-containing protein. (191 aa)
UBA6Ubiquitin like modifier activating enzyme 6. (1052 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
UBA1Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1058 aa)
UBE2D4Ubiquitin conjugating enzyme E2 D4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (139 aa)
CDC34Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (226 aa)
UBE2HUbiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
ENSMLEP00000034242Uncharacterized protein. (173 aa)
ARIH1RBR-type E3 ubiquitin transferase. (407 aa)
UBOX5U-box domain containing 5. (541 aa)
UBE2ZUbiquitin conjugating enzyme E2 Z. (342 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (449 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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