STRINGSTRING
GTF2F2 GTF2F2 GTF2F1 GTF2F1 GTF2E1 GTF2E1 LOC105543372 LOC105543372 CCNH CCNH GTF2E2 GTF2E2 GTF2B GTF2B MNAT1 MNAT1 GTF2H3 GTF2H3 ERCC3 ERCC3 GTF2H4 GTF2H4 ERCC2 ERCC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (545 aa)
GTF2E1General transcription factor IIE subunit 1. (439 aa)
LOC105543372General transcription factor IIH subunit. (380 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
GTF2BGeneral transcription factor IIB. (316 aa)
MNAT1MNAT1 component of CDK activating kinase. (234 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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