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| | ENSMLEP00000000042 | Uncharacterized protein. (348 aa) |
| | ENSMLEP00000000335 | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa) |
| | LOC105528776 | RRM domain-containing protein. (180 aa) |
| | PSIP1 | PC4 and SFRS1 interacting protein 1. (530 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (832 aa) |
| | DNAJC8 | J domain-containing protein. (245 aa) |
| | U2AF1L4 | Uncharacterized protein. (220 aa) |
| | TRA2B | Transformer 2 beta homolog. (288 aa) |
| | DDX20 | DEAD-box helicase 20. (824 aa) |
| | ENSMLEP00000001471 | RRM domain-containing protein. (317 aa) |
| | WDR83 | WD repeat domain 83. (315 aa) |
| | DHX8 | DEAH-box helicase 8. (1142 aa) |
| | C11orf58 | Chromosome 11 open reading frame 58. (183 aa) |
| | SF3B5 | Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa) |
| | DDX39A | DExD-box helicase 39A. (435 aa) |
| | RBM44 | RNA binding motif protein 44. (1055 aa) |
| | LOC105542818 | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa) |
| | ENSMLEP00000002225 | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (249 aa) |
| | BUD13 | BUD13 homolog. (618 aa) |
| | TXNL4A | Thioredoxin like 4A. (71 aa) |
| | SFPQ | RRM domain-containing protein. (340 aa) |
| | HNRNPR | Heterogeneous nuclear ribonucleoprotein R. (620 aa) |
| | WDR25 | WD repeat domain 25. (544 aa) |
| | PRPF40A | Pre-mRNA processing factor 40 homolog A. (912 aa) |
| | CELF6 | Uncharacterized protein. (448 aa) |
| | CCDC130 | Coiled-coil domain containing 130. (398 aa) |
| | LOC105535221 | Uncharacterized protein. (248 aa) |
| | SRSF10 | Serine and arginine rich splicing factor 10. (262 aa) |
| | ENSMLEP00000003707 | SF3A2 domain-containing protein. (182 aa) |
| | LOC105550155 | J domain-containing protein. (254 aa) |
| | PRPF38B | Pre-mRNA processing factor 38B. (546 aa) |
| | YJU2 | YJU2 splicing factor homolog. (307 aa) |
| | CACTIN | Cactin, spliceosome C complex subunit. (741 aa) |
| | DNAJC17 | DnaJ heat shock protein family (Hsp40) member C17. (304 aa) |
| | IK | IK cytokine. (541 aa) |
| | SCNM1 | Sodium channel modifier 1. (195 aa) |
| | SNRNP200 | Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa) |
| | ENSMLEP00000004386 | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa) |
| | SF3B6 | Splicing factor 3b subunit 6. (125 aa) |
| | ENSMLEP00000004525 | Protein kinase domain-containing protein. (144 aa) |
| | METTL3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa) |
| | RNF113A | Ring finger protein 113A. (344 aa) |
| | SNRPB | Small nuclear ribonucleoprotein-associated protein. (240 aa) |
| | METTL14 | Methyltransferase like 14; Belongs to the MT-A70-like family. (456 aa) |
| | ENSMLEP00000005622 | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa) |
| | LSM5 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa) |
| | SRSF2 | Serine and arginine rich splicing factor 2. (189 aa) |
| | SF3B1 | Splicing factor 3b subunit 1. (1200 aa) |
| | ENSMLEP00000006390 | DUF1716 domain-containing protein. (453 aa) |
| | FMC1-LUC7L2 | FMC1-LUC7L2 readthrough. (448 aa) |
| | ENSMLEP00000006771 | Uncharacterized protein. (65 aa) |
| | GEMIN8 | Gem nuclear organelle associated protein 8. (242 aa) |
| | ENSMLEP00000007666 | J domain-containing protein. (218 aa) |
| | LSM4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (231 aa) |
| | GEMIN7 | Gem nuclear organelle associated protein 7. (131 aa) |
| | CELF3 | CUGBP Elav-like family member 3. (466 aa) |
| | DCPS | Decapping enzyme, scavenger. (339 aa) |
| | ZRSR2 | Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2. (456 aa) |
| | ENSMLEP00000008607 | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (70 aa) |
| | SNW1 | SNW domain containing 1. (571 aa) |
| | UBL5 | Ubiquitin like 5. (73 aa) |
| | LOC105554965 | Uncharacterized protein. (436 aa) |
| | SNRPD1 | Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (130 aa) |
| | RBMX2 | RNA binding motif protein X-linked 2. (322 aa) |
| | FRG1 | FSHD region gene 1. (258 aa) |
| | RALY | RALY heterogeneous nuclear ribonucleoprotein. (310 aa) |
| | PQBP1 | Polyglutamine binding protein 1. (265 aa) |
| | ESS2 | Ess-2 splicing factor homolog. (476 aa) |
| | CASC3 | CASC3 exon junction complex subunit. (634 aa) |
| | PPIH | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa) |
| | DDX17 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. (709 aa) |
| | RBM17 | RNA binding motif protein 17. (401 aa) |
| | LOC105555555 | Uncharacterized protein. (237 aa) |
| | SF3B2 | Splicing factor 3b subunit 2. (895 aa) |
| | DHX38 | DEAH-box helicase 38. (1234 aa) |
| | GCFC2 | GC-rich sequence DNA-binding factor 2. (781 aa) |
| | ENSMLEP00000011184 | Uncharacterized protein. (308 aa) |
| | ENSMLEP00000011487 | J domain-containing protein. (172 aa) |
| | SNRPB2 | Small nuclear ribonucleoprotein polypeptide B2. (208 aa) |
| | ENSMLEP00000011554 | Uncharacterized protein. (114 aa) |
| | SRSF5 | Serine and arginine rich splicing factor 5. (272 aa) |
| | ENSMLEP00000011876 | Uncharacterized protein. (213 aa) |
| | USP39 | Ubiquitin specific peptidase 39. (565 aa) |
| | SYF2 | SYF2 pre-mRNA splicing factor. (243 aa) |
| | NOVA2 | NOVA alternative splicing regulator 2. (337 aa) |
| | NCBP1 | Nuclear cap binding protein subunit 1. (790 aa) |
| | PRPF4B | Pre-mRNA processing factor 4B. (1007 aa) |
| | CDC5L | Cell division cycle 5 like. (802 aa) |
| | SMU1 | SMU1 DNA replication regulator and spliceosomal factor. (513 aa) |
| | ENSMLEP00000013046 | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa) |
| | SF3A3 | Splicing factor 3a subunit 3. (501 aa) |
| | ENSMLEP00000013226 | RRM domain-containing protein. (256 aa) |
| | LSM7 | LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa) |
| | RBM41 | RNA binding motif protein 41. (406 aa) |
| | SNRNP70 | Small nuclear ribonucleoprotein U1 subunit 70. (437 aa) |
| | C9orf78 | Chromosome 9 open reading frame 78. (289 aa) |
| | ENSMLEP00000014058 | Sm domain-containing protein. (91 aa) |
| | SNRPG | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (96 aa) |
| | SRSF6 | Serine and arginine rich splicing factor 6. (214 aa) |
| | SRSF4 | Serine and arginine rich splicing factor 4. (494 aa) |
| | SYNCRIP | Synaptotagmin binding cytoplasmic RNA interacting protein. (641 aa) |
| | RSRC1 | Arginine and serine rich coiled-coil 1. (334 aa) |
| | PTBP2 | Polypyrimidine tract binding protein 2. (537 aa) |
| | ENSMLEP00000015587 | Uncharacterized protein. (98 aa) |
| | PRPF31 | Pre-mRNA processing factor 31. (499 aa) |
| | TRA2A | Transformer 2 alpha homolog. (282 aa) |
| | U2AF2 | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (512 aa) |
| | LOC105554451 | RRM domain-containing protein. (260 aa) |
| | ENSMLEP00000016299 | Uncharacterized protein. (54 aa) |
| | PRPF6 | Pre-mRNA processing factor 6. (717 aa) |
| | ENSMLEP00000016685 | Uncharacterized protein. (138 aa) |
| | RBM6 | RNA binding motif protein 6. (580 aa) |
| | ENSMLEP00000016940 | Uncharacterized protein. (318 aa) |
| | EIF4A3 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (354 aa) |
| | GEMIN5 | Gem nuclear organelle associated protein 5. (1482 aa) |
| | EFTUD2 | Elongation factor Tu GTP binding domain containing 2. (972 aa) |
| | ENSMLEP00000018153 | Uncharacterized protein. (372 aa) |
| | GPKOW | G-patch domain and KOW motifs. (476 aa) |
| | CWC25 | CWC25 spliceosome associated protein homolog. (388 aa) |
| | LOC105534884 | RRM domain-containing protein. (352 aa) |
| | PAXBP1 | PAX3 and PAX7 binding protein 1. (917 aa) |
| | SNRPF | Sm domain-containing protein. (127 aa) |
| | RNPC3 | RNA binding region (RNP1, RRM) containing 3. (518 aa) |
| | ISY1 | Uncharacterized protein. (285 aa) |
| | ENSMLEP00000019257 | RRM domain-containing protein. (254 aa) |
| | SNRPC | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (179 aa) |
| | SNRPD2 | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (69 aa) |
| | LSM5-2 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (81 aa) |
| | MFAP1 | Microfibril associated protein 1. (439 aa) |
| | LUC7L3 | LUC7 like 3 pre-mRNA splicing factor. (489 aa) |
| | ENSMLEP00000020013 | annotation not available (74 aa) |
| | SART3 | Spliceosome associated factor 3, U4/U6 recycling protein. (981 aa) |
| | PRMT7 | Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (701 aa) |
| | DBR1 | Debranching RNA lariats 1. (478 aa) |
| | RBM19 | RNA binding motif protein 19. (961 aa) |
| | LOC105548175 | Uncharacterized protein. (181 aa) |
| | ENSMLEP00000020884 | RRM domain-containing protein. (452 aa) |
| | NOVA1 | NOVA alternative splicing regulator 1. (461 aa) |
| | MTHFSD | Methenyltetrahydrofolate synthetase domain containing. (395 aa) |
| | TGS1 | Trimethylguanosine synthase 1. (855 aa) |
| | RBM22 | RNA binding motif protein 22. (420 aa) |
| | LOC105550087 | Uncharacterized protein. (310 aa) |
| | RBM5 | RNA binding motif protein 5. (801 aa) |
| | LOC105533764 | J domain-containing protein. (243 aa) |
| | CRNKL1 | Crooked neck pre-mRNA splicing factor 1. (842 aa) |
| | BUD31 | BUD31 homolog. (144 aa) |
| | ENSMLEP00000021880 | Uncharacterized protein. (522 aa) |
| | LSM6 | LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa) |
| | USP49 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (688 aa) |
| | CWF19L2 | CWF19 like cell cycle control factor 2. (893 aa) |
| | ENSMLEP00000022284 | RRM domain-containing protein. (320 aa) |
| | HTATSF1 | HIV-1 Tat specific factor 1. (754 aa) |
| | SRPK2 | SRSF protein kinase 2. (687 aa) |
| | GEMIN2 | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (277 aa) |
| | CWC15 | CWC15 spliceosome associated protein homolog. (229 aa) |
| | SFSWAP | Splicing factor SWAP. (971 aa) |
| | CDC40 | Cell division cycle 40. (579 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (620 aa) |
| | LSM8-2 | U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa) |
| | PRR3 | Proline rich 3. (188 aa) |
| | LSM3 | U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa) |
| | ENSMLEP00000024071 | Sm domain-containing protein. (71 aa) |
| | RBM42 | RNA binding motif protein 42. (480 aa) |
| | SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (729 aa) |
| | BCAS2 | BCAS2 pre-mRNA processing factor. (225 aa) |
| | CWF19L1 | CWF19 like cell cycle control factor 1. (497 aa) |
| | LOC105535732 | Matrin-type domain-containing protein. (470 aa) |
| | LOC105546285 | RRM domain-containing protein. (286 aa) |
| | WBP4 | WW domain binding protein 4. (375 aa) |
| | ENSMLEP00000025394 | Uncharacterized protein. (200 aa) |
| | KHDC4 | KH domain containing 4, pre-mRNA splicing factor. (614 aa) |
| | ENSMLEP00000025623 | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (90 aa) |
| | XAB2 | XPA binding protein 2. (855 aa) |
| | LSM2 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa) |
| | SNRPD3 | Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa) |
| | SLU7 | SLU7 homolog, splicing factor. (586 aa) |
| | PHF5A | PHD finger protein 5A. (110 aa) |
| | ENSMLEP00000027102 | RRM domain-containing protein. (280 aa) |
| | PLRG1 | Pleiotropic regulator 1. (494 aa) |
| | PRPF8 | Pre-mRNA processing factor 8. (2335 aa) |
| | SNRPA1 | Small nuclear ribonucleoprotein polypeptide A. (255 aa) |
| | WDR77 | WD repeat domain 77. (342 aa) |
| | ENSMLEP00000028280 | Uncharacterized protein. (115 aa) |
| | CTNNBL1 | DUF1716 domain-containing protein. (563 aa) |
| | GEMIN6 | Gem nuclear organelle associated protein 6. (166 aa) |
| | WBP11 | WW domain binding protein 11. (641 aa) |
| | SF3B4 | Splicing factor 3b subunit 4. (424 aa) |
| | HNRNPH3 | Heterogeneous nuclear ribonucleoprotein H3. (346 aa) |
| | RNF113B | Ring finger protein 113B. (298 aa) |
| | SNRPN | Small nuclear ribonucleoprotein-associated protein. (244 aa) |
| | SRSF7 | Serine and arginine rich splicing factor 7. (238 aa) |
| | PPIL3 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (180 aa) |
| | RBM8A | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa) |
| | LSM8 | U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (88 aa) |
| | GEMIN4 | Gem nuclear organelle associated protein 4. (1057 aa) |
| | TFIP11 | Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa) |
| | SNRNP25 | Small nuclear ribonucleoprotein U11/U12 subunit 25. (132 aa) |
| | SNRPA | Small nuclear ribonucleoprotein polypeptide A. (287 aa) |
| | ENSMLEP00000031060 | Matrin-type domain-containing protein. (171 aa) |
| | ENSMLEP00000031093 | Uncharacterized protein. (136 aa) |
| | LOC105554897 | Uncharacterized protein. (305 aa) |
| | NCBP2 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (89 aa) |
| | DHX9 | DExH-box helicase 9. (1275 aa) |
| | SNRNP27 | SNRNP27 domain-containing protein. (119 aa) |
| | HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (602 aa) |
| | LOC105531220 | RRM domain-containing protein. (264 aa) |
| | SNRPC-2 | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (174 aa) |
| | SNIP1 | Smad nuclear interacting protein 1. (396 aa) |
| | PRPF4 | Pre-mRNA processing factor 4. (543 aa) |
| | ENSMLEP00000032493 | RRM domain-containing protein. (350 aa) |
| | SRSF1 | Serine and arginine rich splicing factor 1. (248 aa) |
| | HNRNPC | RRM domain-containing protein. (321 aa) |
| | CLNS1A | Chloride nucleotide-sensitive channel 1A. (237 aa) |
| | PRPF3 | Pre-mRNA processing factor 3. (580 aa) |
| | CD2BP2 | CD2 cytoplasmic tail binding protein 2. (341 aa) |
| | LENG8 | Leukocyte receptor cluster member 8. (838 aa) |
| | MAGOHB | Mago homolog B, exon junction complex subunit. (148 aa) |
| | PPIE | Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa) |
| | CELF1 | CUGBP Elav-like family member 1. (513 aa) |
| | HNRNPA2B1 | Heterogeneous nuclear ribonucleoprotein A2/B1. (353 aa) |
| | DDX41 | DEAD-box helicase 41. (626 aa) |
| | SF1 | Splicing factor 1. (660 aa) |
| | SNRNP35 | Small nuclear ribonucleoprotein U11/U12 subunit 35. (251 aa) |
| | ENSMLEP00000033809 | PWI domain-containing protein. (560 aa) |
| | PRPF38A | Pre-mRNA processing factor 38A. (312 aa) |
| | MTREX | Mtr4 exosome RNA helicase. (1042 aa) |
| | SRSF9 | Serine and arginine rich splicing factor 9. (208 aa) |
| | SCAF11 | SR-related CTD associated factor 11. (1464 aa) |
| | C19orf54 | Chromosome 19 open reading frame 54. (351 aa) |
| | SRSF3 | Serine and arginine rich splicing factor 3. (164 aa) |
| | ZMAT2 | Zinc finger matrin-type 2. (199 aa) |
| | USP4 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (963 aa) |
| | SETX | Senataxin. (2681 aa) |
| | ENSMLEP00000035062 | Uncharacterized protein. (187 aa) |
| | ENSMLEP00000035152 | Uncharacterized protein. (122 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) |
| | SF3A1 | Splicing factor 3a subunit 1. (793 aa) |
| | SRRM2 | Serine/arginine repetitive matrix 2. (2752 aa) |
| | LOC105543371 | Tudor domain-containing protein. (293 aa) |
| | ENSMLEP00000035896 | RRM domain-containing protein. (313 aa) |
| | SNU13 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (158 aa) |
| | YTHDC1 | YTH domain containing 1. (731 aa) |
| | SRSF12 | Serine and arginine rich splicing factor 12. (241 aa) |
| | ENSMLEP00000036212 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (157 aa) |
| | HNRNPM | Heterogeneous nuclear ribonucleoprotein M. (730 aa) |
| | LOC105554415 | Uncharacterized protein. (139 aa) |
| | PRPF39 | Pre-mRNA processing factor 39. (669 aa) |
| | CWC22 | CWC22 spliceosome associated protein homolog. (907 aa) |
| | STRAP | Serine/threonine kinase receptor associated protein. (363 aa) |
| | RBM10 | RNA binding motif protein 10. (995 aa) |
| | MAGOH | Mago homolog, exon junction complex subunit. (149 aa) |
| | ZCRB1 | Zinc finger CCHC-type and RNA binding motif containing 1. (217 aa) |
| | PRPF19 | Pre-mRNA processing factor 19. (504 aa) |
| | ALYREF | Aly/REF export factor. (207 aa) |
| | SNRPE | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa) |
| | GPATCH11 | G-patch domain containing 11. (287 aa) |
| | PPIL1 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa) |
| | TXNL4B | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa) |
| | AQR | RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1480 aa) |
| | DDX39B | DExD-box helicase 39B. (428 aa) |
| | DHX16 | DEAH-box helicase 16. (1044 aa) |
| | GPATCH1 | G-patch domain containing 1. (831 aa) |
| | ESRP2 | Epithelial splicing regulatory protein 2. (618 aa) |
| | PRPF40B | Pre-mRNA processing factor 40 homolog B. (871 aa) |
| | SF3B3 | Splicing factor 3b subunit 3. (1197 aa) |
| | LUC7L | LUC7 like. (380 aa) |
| | HNRNPA1 | Heterogeneous nuclear ribonucleoprotein A1. (372 aa) |
