19 items (Mandrillus leucophaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	BRIP1	BRCA1 interacting protein C-terminal helicase 1. (1247 aa)
	SMARCAD1	Uncharacterized protein. (1026 aa)
	LOC105534329	UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
	SLX4	SLX4 structure-specific endonuclease subunit. (1736 aa)
	ENSMLEP00000005424	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
	LOC105537674	UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
	SLX1A	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (275 aa)
	DNA2	DNA replication helicase/nuclease 2. (898 aa)
	ENSMLEP00000014080	Uncharacterized protein. (103 aa)
	RAD52	RAD52 homolog, DNA repair protein. (400 aa)
	BLM	BLM RecQ like helicase. (1392 aa)
	UBE2V2	Ubiquitin conjugating enzyme E2 V2. (155 aa)
	HELQ	Helicase, POLQ like. (1061 aa)
	ENSMLEP00000024034	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
	C14orf39	Chromosome 14 open reading frame 39. (587 aa)
	SETMAR	SET domain and mariner transposase fusion gene. (684 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (396 aa)
	EXD2	Exonuclease 3'-5' domain containing 2. (620 aa)
	RBBP8	RB binding protein 8, endonuclease. (886 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLM	BRIP1	ENSMLEP00000017525	ENSMLEP00000026839	BLM RecQ like helicase.	BRCA1 interacting protein C-terminal helicase 1.	0.708
BLM	DNA2	ENSMLEP00000017525	ENSMLEP00000011048	BLM RecQ like helicase.	DNA replication helicase/nuclease 2.	0.943
BLM	ENSMLEP00000014080	ENSMLEP00000017525	ENSMLEP00000014080	BLM RecQ like helicase.	Uncharacterized protein.	0.898
BLM	EXD2	ENSMLEP00000017525	ENSMLEP00000040231	BLM RecQ like helicase.	Exonuclease 3'-5' domain containing 2.	0.436
BLM	HELQ	ENSMLEP00000017525	ENSMLEP00000021967	BLM RecQ like helicase.	Helicase, POLQ like.	0.438
BLM	RAD52	ENSMLEP00000017525	ENSMLEP00000014779	BLM RecQ like helicase.	RAD52 homolog, DNA repair protein.	0.898
BLM	RBBP8	ENSMLEP00000017525	ENSMLEP00000040885	BLM RecQ like helicase.	RB binding protein 8, endonuclease.	0.782
BLM	SLX1A	ENSMLEP00000017525	ENSMLEP00000008704	BLM RecQ like helicase.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	0.935
BLM	SLX4	ENSMLEP00000017525	ENSMLEP00000025679	BLM RecQ like helicase.	SLX4 structure-specific endonuclease subunit.	0.718
BLM	SMARCAD1	ENSMLEP00000017525	ENSMLEP00000028275	BLM RecQ like helicase.	Uncharacterized protein.	0.518
BLM	SPO11	ENSMLEP00000017525	ENSMLEP00000038661	BLM RecQ like helicase.	SPO11 initiator of meiotic double stranded breaks.	0.468
BRIP1	BLM	ENSMLEP00000026839	ENSMLEP00000017525	BRCA1 interacting protein C-terminal helicase 1.	BLM RecQ like helicase.	0.708
BRIP1	DNA2	ENSMLEP00000026839	ENSMLEP00000011048	BRCA1 interacting protein C-terminal helicase 1.	DNA replication helicase/nuclease 2.	0.652
BRIP1	ENSMLEP00000014080	ENSMLEP00000026839	ENSMLEP00000014080	BRCA1 interacting protein C-terminal helicase 1.	Uncharacterized protein.	0.522
BRIP1	EXD2	ENSMLEP00000026839	ENSMLEP00000040231	BRCA1 interacting protein C-terminal helicase 1.	Exonuclease 3'-5' domain containing 2.	0.449
BRIP1	RAD52	ENSMLEP00000026839	ENSMLEP00000014779	BRCA1 interacting protein C-terminal helicase 1.	RAD52 homolog, DNA repair protein.	0.522
BRIP1	RBBP8	ENSMLEP00000026839	ENSMLEP00000040885	BRCA1 interacting protein C-terminal helicase 1.	RB binding protein 8, endonuclease.	0.686
BRIP1	SLX1A	ENSMLEP00000026839	ENSMLEP00000008704	BRCA1 interacting protein C-terminal helicase 1.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	0.568
BRIP1	SLX4	ENSMLEP00000026839	ENSMLEP00000025679	BRCA1 interacting protein C-terminal helicase 1.	SLX4 structure-specific endonuclease subunit.	0.653
DNA2	BLM	ENSMLEP00000011048	ENSMLEP00000017525	DNA replication helicase/nuclease 2.	BLM RecQ like helicase.	0.943