50 items (Mandrillus leucophaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARL2	ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (182 aa)
	PRKAA2	Non-specific serine/threonine protein kinase. (542 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
	IGF1	Insulin like growth factor 1. (159 aa)
	ENSMLEP00000007059	Uncharacterized protein. (169 aa)
	HTR2A	5-hydroxytryptamine receptor 2A. (471 aa)
	LOC105534833	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (252 aa)
	FBP1	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (298 aa)
	ACTN3	Actinin alpha 3 (gene/pseudogene). (916 aa)
	CBFA2T3	CBFA2/RUNX1 partner transcriptional co-repressor 3. (589 aa)
	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
	STAT3	Signal transducer and activator of transcription. (693 aa)
	SIRT6	Sirtuin 6. (355 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (758 aa)
	FLCN	Folliculin. (515 aa)
	INSR	Tyrosine-protein kinase receptor. (1301 aa)
	ZBTB20	Zinc finger and BTB domain containing 20. (741 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	NCOR1	Nuclear receptor corepressor 1. (2404 aa)
	LOC105530911	Uncharacterized protein. (251 aa)
	SLC4A1	Anion exchange protein. (928 aa)
	GIT1	GIT ArfGAP 1. (754 aa)
	ENSMLEP00000020744	Uncharacterized protein. (107 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (365 aa)
	SLC2A6	Solute carrier family 2 member 6; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (507 aa)
	LOC105533626	Uncharacterized protein. (220 aa)
	JMJD8	Jumonji domain containing 8. (236 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1085 aa)
	PRKAG2	Protein kinase AMP-activated non-catalytic subunit gamma 2. (506 aa)
	PRXL2C	Uncharacterized protein. (232 aa)
	MLXIPL	MLX interacting protein like. (784 aa)
	MLST8	MTOR associated protein, LST8 homolog. (335 aa)
	GCK	Phosphotransferase. (466 aa)
	EP300	E1A binding protein p300. (2411 aa)
	APP	Amyloid beta precursor protein. (772 aa)
	RPTOR	Regulatory associated protein of MTOR complex 1. (1291 aa)
	PRKAG1	Protein kinase AMP-activated non-catalytic subunit gamma 1. (326 aa)
	GPD1	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa)
	TIGAR	TP53 induced glycolysis regulatory phosphatase. (270 aa)
	ENSMLEP00000033425	Uncharacterized protein. (234 aa)
	PGAM1	Uncharacterized protein. (205 aa)
	DDIT4	DNA damage inducible transcript 4. (233 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (559 aa)
	ENSMLEP00000034499	Uncharacterized protein. (244 aa)
	NUPR1	Nuclear protein 1, transcriptional regulator. (100 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator. (734 aa)
	SLC4A4	Anion exchange protein. (1100 aa)
	ZBTB7A	Zinc finger and BTB domain containing 7A. (347 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	EP300	ENSMLEP00000031445	ENSMLEP00000031242	Amyloid beta precursor protein.	E1A binding protein p300.	0.489
APP	PSEN1	ENSMLEP00000031445	ENSMLEP00000019312	Amyloid beta precursor protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.978
ARNT	EP300	ENSMLEP00000039521	ENSMLEP00000031242	Aryl hydrocarbon receptor nuclear translocator.	E1A binding protein p300.	0.938
ARNT	HIF1A	ENSMLEP00000039521	ENSMLEP00000016423	Aryl hydrocarbon receptor nuclear translocator.	Hypoxia inducible factor 1 subunit alpha.	0.996
CBFA2T3	NCOR1	ENSMLEP00000010936	ENSMLEP00000019612	CBFA2/RUNX1 partner transcriptional co-repressor 3.	Nuclear receptor corepressor 1.	0.650
DDIT4	EP300	ENSMLEP00000034221	ENSMLEP00000031242	DNA damage inducible transcript 4.	E1A binding protein p300.	0.483
DDIT4	RPTOR	ENSMLEP00000034221	ENSMLEP00000031715	DNA damage inducible transcript 4.	Regulatory associated protein of MTOR complex 1.	0.485
DDIT4	STAT3	ENSMLEP00000034221	ENSMLEP00000012622	DNA damage inducible transcript 4.	Signal transducer and activator of transcription.	0.483
ENSMLEP00000020744	P2RX7	ENSMLEP00000020744	ENSMLEP00000038537	Uncharacterized protein.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.598
EP300	APP	ENSMLEP00000031242	ENSMLEP00000031445	E1A binding protein p300.	Amyloid beta precursor protein.	0.489
EP300	ARNT	ENSMLEP00000031242	ENSMLEP00000039521	E1A binding protein p300.	Aryl hydrocarbon receptor nuclear translocator.	0.938
EP300	DDIT4	ENSMLEP00000031242	ENSMLEP00000034221	E1A binding protein p300.	DNA damage inducible transcript 4.	0.483
EP300	HDAC4	ENSMLEP00000031242	ENSMLEP00000025074	E1A binding protein p300.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.606
EP300	HIF1A	ENSMLEP00000031242	ENSMLEP00000016423	E1A binding protein p300.	Hypoxia inducible factor 1 subunit alpha.	0.996
EP300	NCOR1	ENSMLEP00000031242	ENSMLEP00000019612	E1A binding protein p300.	Nuclear receptor corepressor 1.	0.855
EP300	PPARA	ENSMLEP00000031242	ENSMLEP00000021307	E1A binding protein p300.	Peroxisome proliferator activated receptor alpha.	0.840
EP300	STAT3	ENSMLEP00000031242	ENSMLEP00000012622	E1A binding protein p300.	Signal transducer and activator of transcription.	0.968
FBP1	GCK	ENSMLEP00000008458	ENSMLEP00000030794	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family.	Phosphotransferase.	0.509
FBP1	TIGAR	ENSMLEP00000008458	ENSMLEP00000033301	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family.	TP53 induced glycolysis regulatory phosphatase.	0.912
FLCN	MLST8	ENSMLEP00000016513	ENSMLEP00000029859	Folliculin.	MTOR associated protein, LST8 homolog.	0.488