STRINGSTRING
SLC8A1 SLC8A1 CAMK2D CAMK2D LOC105533617 LOC105533617 ATP2C1 ATP2C1 ATP2A1 ATP2A1 DRD5 DRD5 ATP2B2 ATP2B2 TGFB1 TGFB1 TCIRG1 TCIRG1 TPT1 TPT1 TMEM203 TMEM203 BAX BAX EDN1 EDN1 SCGN SCGN P2RX1 P2RX1 DHRS7C DHRS7C TRPM8 TRPM8 STIM2 STIM2 ADCY8 ADCY8 TUNAR TUNAR ATF4 ATF4 HTR2B HTR2B PLN PLN BCL2 BCL2 VAPB VAPB P2RY1 P2RY1 IMMT IMMT PML PML CCL14 CCL14 ENSMLEP00000006859 ENSMLEP00000006859 ENSMLEP00000006898 ENSMLEP00000006898 NPTN NPTN ELANE ELANE GPR3 GPR3 MCUB MCUB SV2A SV2A RAP1GDS1 RAP1GDS1 CDH5 CDH5 HTR2A HTR2A DRD1 DRD1 MICU1 MICU1 CASR CASR SLC10A7 SLC10A7 THADA THADA ITPR1 ITPR1 RYR2 RYR2 ENSMLEP00000009906 ENSMLEP00000009906 CAV1 CAV1 ATP2A3 ATP2A3 LOC105539434 LOC105539434 ATP13A5 ATP13A5 LOC105533973 LOC105533973 SLC24A3 SLC24A3 CD40 CD40 DRD3 DRD3 CCL15 CCL15 TRPC5 TRPC5 SLC24A4 SLC24A4 CXCL12 CXCL12 TRPC4 TRPC4 RMDN3 RMDN3 ENSMLEP00000013741 ENSMLEP00000013741 EDN3 EDN3 GRIK2 GRIK2 SLC8A3 SLC8A3 ENSMLEP00000014901 ENSMLEP00000014901 ENSMLEP00000014973 ENSMLEP00000014973 CSRP3 CSRP3 ENSMLEP00000015528 ENSMLEP00000015528 ATP2C2 ATP2C2 EDNRA EDNRA RMDN2 RMDN2 PTH1R PTH1R FIS1 FIS1 HCRTR2 HCRTR2 TRPC7 TRPC7 STIM1 STIM1 TMEM178A TMEM178A TRPC3 TRPC3 ATP2B3 ATP2B3 ANK2 ANK2 YWHAE YWHAE BAK1 BAK1 MCUR1 MCUR1 PSEN1 PSEN1 PDZD8 PDZD8 ENSMLEP00000019850 ENSMLEP00000019850 CDH23 CDH23 BOK BOK TRDN TRDN CAV3 CAV3 TMTC4 TMTC4 ENSMLEP00000020666 ENSMLEP00000020666 AFG3L2 AFG3L2 CCL13 CCL13 LOC105549269 LOC105549269 CALB1 CALB1 GCM2 GCM2 ATP2B4 ATP2B4 PTH PTH TNNI3 TNNI3 BNIP3 BNIP3 ANXA6 ANXA6 TRPV4 TRPV4 FATE1 FATE1 PRKCB PRKCB TMEM165 TMEM165 FKBP1B FKBP1B MICU2 MICU2 CCDC47 CCDC47 CCL1 CCL1 GRM1 GRM1 C19orf12 C19orf12 ATP13A2 ATP13A2 DISC1 DISC1 TRPA1 TRPA1 HEXB HEXB CALCB CALCB KEL KEL SLC37A4 SLC37A4 TRPC6 TRPC6 GRIA1 GRIA1 MICU3 MICU3 WNT5A WNT5A PIK3CB PIK3CB PKD2 PKD2 UMOD UMOD ATP2B1 ATP2B1 ENSMLEP00000029067 ENSMLEP00000029067 CASQ2 CASQ2 ATP13A1 ATP13A1 SLC8B1 SLC8B1 STOML2 STOML2 SLC24A1 SLC24A1 HCRTR1 HCRTR1 RYR1 RYR1 SLC30A1 SLC30A1 ATP2A2 ATP2A2 VDR VDR DMPK DMPK CALB2 CALB2 APP APP KCTD17 KCTD17 TGM2 TGM2 TRPC1 TRPC1 TSPOAP1 TSPOAP1 SLC25A23 SLC25A23 LETM1 LETM1 SYPL2 SYPL2 SLC24A2 SLC24A2 HRC HRC ATP7B ATP7B MAIP1 MAIP1 CCL8 CCL8 SLC24A5 SLC24A5 RGN RGN SLC8A2 SLC8A2 SMDT1 SMDT1 STC1 STC1 MCU MCU CHRNA7 CHRNA7 TPCN2 TPCN2 GPER1 GPER1 GRM5 GRM5 SLC35G1 SLC35G1 MYH7B MYH7B ATP13A4 ATP13A4 PACS2 PACS2 GRINA GRINA PKHD1 PKHD1 RYR3 RYR3 TMCO1 TMCO1 F2 F2 WFS1 WFS1 CALCA CALCA DRD2 DRD2 CHERP CHERP
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (441 aa)
LOC105533617C-C motif chemokine. (92 aa)
ATP2C1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (973 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1027 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (478 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1230 aa)
TGFB1Transforming growth factor beta 1. (226 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
TPT1Tumor protein, translationally-controlled 1; Belongs to the TCTP family. (196 aa)
TMEM203Transmembrane protein 203. (136 aa)
BAXBCL2 associated X, apoptosis regulator. (203 aa)
EDN1Endothelin 1. (211 aa)
SCGNSecretagogin, EF-hand calcium binding protein. (276 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
DHRS7CDehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
STIM2Stromal interaction molecule 2. (724 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
TUNARTCL1 upstream neural differentiation-associated RNA. (48 aa)
ATF4Activating transcription factor 4. (351 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
VAPBVAMP associated protein B and C. (138 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
IMMTMICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (758 aa)
PMLPromyelocytic leukemia. (858 aa)
CCL14C-C motif chemokine. (108 aa)
ENSMLEP0000000685914_3_3 domain-containing protein; Belongs to the 14-3-3 family. (196 aa)
ENSMLEP00000006898Uncharacterized protein. (117 aa)
NPTNNeuroplastin. (398 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (263 aa)
GPR3G protein-coupled receptor 3; Belongs to the G-protein coupled receptor 1 family. (330 aa)
MCUBMitochondrial calcium uniporter dominant negative beta subunit. (303 aa)
SV2ASynaptic vesicle glycoprotein 2A. (742 aa)
RAP1GDS1Rap1 GTPase-GDP dissociation stimulator 1. (606 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (705 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
MICU1Uncharacterized protein. (482 aa)
CASRCalcium sensing receptor. (1088 aa)
SLC10A7Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (358 aa)
THADATHADA armadillo repeat containing. (1933 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2731 aa)
RYR2Ryanodine receptor 2. (4862 aa)
ENSMLEP00000009906TCTP domain-containing protein; Belongs to the TCTP family. (124 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
ATP2A3ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (900 aa)
LOC105539434Uncharacterized protein. (279 aa)
ATP13A5Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1218 aa)
LOC105533973AAA domain-containing protein. (741 aa)
SLC24A3Solute carrier family 24 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (596 aa)
CD40CD40 molecule. (278 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
CCL15C-C motif chemokine. (111 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
SLC24A4Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (622 aa)
CXCL12SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (458 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
RMDN3Regulator of microtubule dynamics 3. (471 aa)
ENSMLEP00000013741ANF_receptor domain-containing protein. (295 aa)
EDN3Endothelin 3. (211 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
ENSMLEP00000014901TCTP domain-containing protein; Belongs to the TCTP family. (145 aa)
ENSMLEP00000014973MSP domain-containing protein. (91 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
ENSMLEP00000015528Uncharacterized protein. (184 aa)
ATP2C2ATPase secretory pathway Ca2+ transporting 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (908 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
RMDN2Regulator of microtubule dynamics 2. (573 aa)
PTH1RParathyroid hormone 1 receptor; Belongs to the G-protein coupled receptor 2 family. (782 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
HCRTR2Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family. (444 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (863 aa)
STIM1Stromal interaction molecule 1. (790 aa)
TMEM178ATransmembrane protein 178A. (163 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (849 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
ANK2Ankyrin 2. (3938 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
MCUR1Mitochondrial calcium uniporter regulator 1. (216 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
PDZD8PDZ domain containing 8. (1078 aa)
ENSMLEP00000019850TCTP domain-containing protein; Belongs to the TCTP family. (180 aa)
CDH23Cadherin related 23. (3313 aa)
BOKUncharacterized protein. (369 aa)
TRDNTriadin. (725 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
TMTC4Transmembrane O-mannosyltransferase targeting cadherins 4. (764 aa)
ENSMLEP00000020666EF-hand domain-containing protein. (462 aa)
AFG3L2AFG3 like matrix AAA peptidase subunit 2. (769 aa)
CCL13C-C motif chemokine. (98 aa)
LOC105549269TRP_2 domain-containing protein. (780 aa)
CALB1Calbindin 1. (261 aa)
GCM2Glial cells missing transcription factor 2. (426 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1241 aa)
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
BNIP3BCL2 interacting protein 3. (215 aa)
ANXA6Annexin. (676 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
FATE1Fetal and adult testis expressed 1. (183 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
TMEM165GDT1 family protein. (318 aa)
FKBP1BPeptidylprolyl isomerase. (95 aa)
MICU2Mitochondrial calcium uptake 2. (362 aa)
CCDC47Coiled-coil domain containing 47. (483 aa)
CCL1C-C motif chemokine. (96 aa)
GRM1Glutamate metabotropic receptor 1. (961 aa)
C19orf12Chromosome 19 open reading frame 12. (144 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1182 aa)
DISC1DISC1 scaffold protein. (858 aa)
TRPA1Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1119 aa)
HEXBHexosaminidase subunit beta. (463 aa)
CALCBCalcitonin related polypeptide beta. (138 aa)
KELKell metallo-endopeptidase (Kell blood group). (732 aa)
SLC37A4Solute carrier family 37 member 4. (451 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
MICU3Mitochondrial calcium uptake family member 3. (422 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
PKD2EF-hand domain-containing protein. (386 aa)
UMODUromodulin. (649 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
ENSMLEP00000029067Uncharacterized protein. (101 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (400 aa)
ATP13A1Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1304 aa)
SLC8B1Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (593 aa)
STOML2Stomatin like 2. (361 aa)
SLC24A1Solute carrier family 24 member 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1098 aa)
HCRTR1Hypocretin receptor 1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
RYR1Ryanodine receptor 1. (4628 aa)
SLC30A1Solute carrier family 30 member 1. (507 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1024 aa)
VDRVitamin D receptor. (477 aa)
DMPKDM1 protein kinase. (630 aa)
CALB2Calbindin 2. (271 aa)
APPAmyloid beta precursor protein. (772 aa)
KCTD17Potassium channel tetramerization domain containing 17. (282 aa)
TGM2Transglutaminase 2. (687 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (809 aa)
TSPOAP1TSPO associated protein 1. (1877 aa)
SLC25A23Solute carrier family 25 member 23; Belongs to the mitochondrial carrier (TC 2.A.29) family. (404 aa)
LETM1Leucine zipper and EF-hand containing transmembrane protein 1. (736 aa)
SYPL2Synaptophysin like 2. (272 aa)
SLC24A2Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (664 aa)
HRCHistidine rich calcium binding protein. (697 aa)
ATP7BATPase copper transporting beta. (1470 aa)
MAIP1Matrix AAA peptidase interacting protein 1. (291 aa)
CCL8C-C motif chemokine. (99 aa)
SLC24A5Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (500 aa)
RGNRegucalcin. (299 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (921 aa)
SMDT1Single-pass membrane protein with aspartate rich tail 1. (107 aa)
STC1Stanniocalcin 1. (247 aa)
MCUMitochondrial calcium uniporter. (318 aa)
CHRNA7Uncharacterized protein. (473 aa)
TPCN2Two pore segment channel 2. (752 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
GRM5Glutamate metabotropic receptor 5. (1039 aa)
SLC35G1Solute carrier family 35 member G1. (325 aa)
MYH7BMyosin heavy chain 7B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2028 aa)
ATP13A4Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1196 aa)
PACS2Phosphofurin acidic cluster sorting protein 2. (865 aa)
GRINAGlutamate ionotropic receptor NMDA type subunit associated protein 1. (371 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4000 aa)
RYR3Ryanodine receptor 3. (4804 aa)
TMCO1Transmembrane and coiled-coil domains 1. (239 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
WFS1Wolframin ER transmembrane glycoprotein. (890 aa)
CALCACalcitonin related polypeptide alpha. (140 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
CHERPCalcium homeostasis endoplasmic reticulum protein. (781 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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