58 items (Mandrillus leucophaeus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Predicted Interactions

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gene fusions

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protein homology

Your Input:
	SNRPC-2	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (174 aa)
	SMNDC1	Survival motor neuron domain containing 1. (234 aa)
	FBLL1	Fibrillarin like 1. (312 aa)
	PRPF4	Pre-mRNA processing factor 4. (543 aa)
	PRPF3	Pre-mRNA processing factor 3. (580 aa)
	NOLC1	Nucleolar and coiled-body phosphoprotein 1. (711 aa)
	NOP10	NOP10 ribonucleoprotein. (64 aa)
	ENSMLEP00000033809	PWI domain-containing protein. (560 aa)
	GAR1	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (218 aa)
	FAM118B	Family with sequence similarity 118 member B. (351 aa)
	CDK2	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
	EWSR1	EWS RNA binding protein 1. (661 aa)
	WRAP53	WD repeat containing antisense to TP53. (531 aa)
	ELL	Elongation factor for RNA polymerase II. (488 aa)
	LSM10	LSM10, U7 small nuclear RNA associated. (123 aa)
	USPL1	Ubiquitin specific peptidase like 1. (1092 aa)
	EAF1	ELL associated factor 1. (268 aa)
	NHP2	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (153 aa)
	TOE1	Target of EGR1, exonuclease. (519 aa)
	FRG1	FSHD region gene 1. (258 aa)
	ENSMLEP00000009809	Ribosomal_L7Ae domain-containing protein. (129 aa)
	COIL	Coilin. (576 aa)
	ZC3H8	Zinc finger CCCH-type containing 8. (295 aa)
	USH1G	USH1 protein network component sans. (429 aa)
	ANGEL2	Angel homolog 2. (544 aa)
	PRPF31	Pre-mRNA processing factor 31. (499 aa)
	XPO1	Exportin 1. (1070 aa)
	OIP5	Opa interacting protein 5. (229 aa)
	EFTUD2	Elongation factor Tu GTP binding domain containing 2. (972 aa)
	ZPR1	ZPR1 zinc finger. (459 aa)
	ICE1	Interactor of little elongation complex ELL subunit 1. (2239 aa)
	HSPB7	Heat shock protein family B (small) member 7; Belongs to the small heat shock protein (HSP20) family. (253 aa)
	DDX46	DEAD-box helicase 46. (1031 aa)
	SNRPC	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (179 aa)
	SART3	Spliceosome associated factor 3, U4/U6 recycling protein. (981 aa)
	DKC1	Dyskerin pseudouridine synthase 1. (514 aa)
	AK6	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
	TGS1	Trimethylguanosine synthase 1. (855 aa)
	ICE2	Interactor of little elongation complex ELL subunit 2. (982 aa)
	ANKS1B	Ankyrin repeat and sterile alpha motif domain containing 1B. (1248 aa)
	TRIM22	Tripartite motif containing 22. (498 aa)
	SART1	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (729 aa)
	PHAX	Phosphorylated adaptor for RNA export. (394 aa)
	RDM1	RAD52 motif containing 1. (284 aa)
	LOC105542361	HNF-1_N domain-containing protein. (198 aa)
	FBL	Fibrillarin. (318 aa)
	ZNF473	Zinc finger protein 473. (871 aa)
	HABP4	Hyaluronan binding protein 4. (373 aa)
	HINFP	Histone H4 transcription factor. (517 aa)
	LOC105543371	Tudor domain-containing protein. (293 aa)
	ARIH1	RBR-type E3 ubiquitin transferase. (407 aa)
	ENSMLEP00000026658	Coilin_N domain-containing protein. (478 aa)
	NOP58	NOP58 ribonucleoprotein. (537 aa)
	ISG20	Interferon stimulated exonuclease gene 20. (181 aa)
	LSG1	Large 60S subunit nuclear export GTPase 1. (658 aa)
	NPAT	Nuclear protein, coactivator of histone transcription. (1421 aa)
	GEMIN4	Gem nuclear organelle associated protein 4. (1057 aa)
	ENSMLEP00000031060	Matrin-type domain-containing protein. (171 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK6	ENSMLEP00000009809	ENSMLEP00000020997	ENSMLEP00000009809	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	Ribosomal_L7Ae domain-containing protein.	0.707
AK6	NHP2	ENSMLEP00000020997	ENSMLEP00000008844	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.707
ARIH1	CDK2	ENSMLEP00000035511	ENSMLEP00000001075	RBR-type E3 ubiquitin transferase.	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	0.649
CDK2	ARIH1	ENSMLEP00000001075	ENSMLEP00000035511	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	RBR-type E3 ubiquitin transferase.	0.649
CDK2	NPAT	ENSMLEP00000001075	ENSMLEP00000029913	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Nuclear protein, coactivator of histone transcription.	0.515
CDK2	XPO1	ENSMLEP00000001075	ENSMLEP00000015809	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Exportin 1.	0.554
DDX46	EFTUD2	ENSMLEP00000018932	ENSMLEP00000017536	DEAD-box helicase 46.	Elongation factor Tu GTP binding domain containing 2.	0.613
DDX46	ENSMLEP00000031060	ENSMLEP00000018932	ENSMLEP00000031060	DEAD-box helicase 46.	Matrin-type domain-containing protein.	0.715
DDX46	ENSMLEP00000033809	ENSMLEP00000018932	ENSMLEP00000033809	DEAD-box helicase 46.	PWI domain-containing protein.	0.465
DDX46	LSM10	ENSMLEP00000018932	ENSMLEP00000005814	DEAD-box helicase 46.	LSM10, U7 small nuclear RNA associated.	0.947
DDX46	NOP58	ENSMLEP00000018932	ENSMLEP00000028623	DEAD-box helicase 46.	NOP58 ribonucleoprotein.	0.484
DDX46	PRPF3	ENSMLEP00000018932	ENSMLEP00000032822	DEAD-box helicase 46.	Pre-mRNA processing factor 3.	0.465
DDX46	PRPF4	ENSMLEP00000018932	ENSMLEP00000032174	DEAD-box helicase 46.	Pre-mRNA processing factor 4.	0.442
DDX46	SART1	ENSMLEP00000018932	ENSMLEP00000024210	DEAD-box helicase 46.	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.	0.581
DDX46	SMNDC1	ENSMLEP00000018932	ENSMLEP00000032045	DEAD-box helicase 46.	Survival motor neuron domain containing 1.	0.949
DDX46	SNRPC	ENSMLEP00000018932	ENSMLEP00000019385	DEAD-box helicase 46.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]	0.715
DDX46	SNRPC-2	ENSMLEP00000018932	ENSMLEP00000032015	DEAD-box helicase 46.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]	0.715
DKC1	ENSMLEP00000009809	ENSMLEP00000020471	ENSMLEP00000009809	Dyskerin pseudouridine synthase 1.	Ribosomal_L7Ae domain-containing protein.	0.995
DKC1	FBL	ENSMLEP00000020471	ENSMLEP00000037802	Dyskerin pseudouridine synthase 1.	Fibrillarin.	0.991
DKC1	FBLL1	ENSMLEP00000020471	ENSMLEP00000032067	Dyskerin pseudouridine synthase 1.	Fibrillarin like 1.	0.990