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RAP1A RAP1A SYT2 SYT2 ENSMLEP00000009668 ENSMLEP00000009668 SYT9 SYT9 RIMS1 RIMS1 SNAP25 SNAP25 BLOC1S6 BLOC1S6 STX1A STX1A BRAF BRAF DNAJC5 DNAJC5 VAMP1 VAMP1 RIMS3 RIMS3 SCRIB SCRIB P2RX7 P2RX7 CADPS2 CADPS2 NAPA NAPA CTBP2 CTBP2 CADPS CADPS SYT1 SYT1 SNAPIN SNAPIN ENSMLEP00000012301 ENSMLEP00000012301 ERC2 ERC2 ENSMLEP00000013488 ENSMLEP00000013488 CPLX4 CPLX4 ENSMLEP00000014628 ENSMLEP00000014628 PIP5K1C PIP5K1C SYT7 SYT7 UNC13C UNC13C PSEN1 PSEN1 CDK5 CDK5 UNC13A UNC13A ENSMLEP00000020744 ENSMLEP00000020744 CPLX3 CPLX3 UNC13B UNC13B STX1B STX1B PPFIA3 PPFIA3 ENSMLEP00000025021 ENSMLEP00000025021 SYNJ1 SYNJ1 CPLX2 CPLX2 PRRT2 PRRT2 ENSMLEP00000026939 ENSMLEP00000026939 STX2 STX2 STX4 STX4 LRRC1 LRRC1 SNAP23 SNAP23 STX3 STX3 DOC2B DOC2B NLGN1 NLGN1 SYT8 SYT8 DOC2A DOC2A STX11 STX11 ENSMLEP00000003309 ENSMLEP00000003309 SYT5 SYT5 SV2A SV2A OTOF OTOF SNAP47 SNAP47 SYT12 SYT12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
SYT2Synaptotagmin 2. (419 aa)
ENSMLEP00000009668Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (383 aa)
SYT9Synaptotagmin 9. (491 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1692 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (172 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (745 aa)
DNAJC5J domain-containing protein. (219 aa)
VAMP1Vesicle associated membrane protein 1. (118 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
SCRIBScribble planar cell polarity protein. (1445 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
CADPS2Calcium dependent secretion activator 2. (1242 aa)
NAPANSF attachment protein alpha. (295 aa)
CTBP2C-terminal binding protein 2. (985 aa)
CADPSCalcium dependent secretion activator. (1242 aa)
SYT1Synaptotagmin 1. (422 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
ENSMLEP00000012301Protein kinase domain-containing protein. (294 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (957 aa)
ENSMLEP00000013488C2 domain-containing protein. (356 aa)
CPLX4Complexin 4. (160 aa)
ENSMLEP00000014628Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (430 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (669 aa)
SYT7Synaptotagmin 7. (684 aa)
UNC13CUnc-13 homolog C. (2186 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (302 aa)
UNC13AUnc-13 homolog A. (1520 aa)
ENSMLEP00000020744Uncharacterized protein. (107 aa)
CPLX3Complexin 3. (158 aa)
UNC13BUncharacterized protein. (4338 aa)
STX1BSyntaxin 1B; Belongs to the syntaxin family. (245 aa)
PPFIA3PTPRF interacting protein alpha 3. (1160 aa)
ENSMLEP00000025021Uncharacterized protein. (1217 aa)
SYNJ1Synaptojanin 1. (1614 aa)
CPLX2Complexin 2. (134 aa)
PRRT2Proline rich transmembrane protein 2. (347 aa)
ENSMLEP00000026939J domain-containing protein. (135 aa)
STX2Syntaxin 2; Belongs to the syntaxin family. (278 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
LRRC1Leucine rich repeat containing 1. (507 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (290 aa)
DOC2BDouble C2 domain beta. (357 aa)
NLGN1Neuroligin 1. (823 aa)
SYT8Synaptotagmin 8. (387 aa)
DOC2ADouble C2-like domain-containing protein. (400 aa)
STX11Syntaxin 11; Belongs to the syntaxin family. (287 aa)
ENSMLEP00000003309PDZ domain-containing protein. (442 aa)
SYT5Synaptotagmin 5. (386 aa)
SV2ASynaptic vesicle glycoprotein 2A. (742 aa)
OTOFOtoferlin. (1848 aa)
SNAP47Synaptosome associated protein 47. (419 aa)
SYT12Synaptotagmin 12. (421 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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