STRINGSTRING
ARL4C ARL4C ENSMLEP00000007799 ENSMLEP00000007799 ENSMLEP00000008672 ENSMLEP00000008672 VPS35 VPS35 HGS HGS VPS35L VPS35L UBAP1 UBAP1 ERC1 ERC1 ACAP2 ACAP2 VPS26A VPS26A PTPN23 PTPN23 GRIP2 GRIP2 AP3D1 AP3D1 PIKFYVE PIKFYVE STX16 STX16 TBC1D14 TBC1D14 HEATR5B HEATR5B CCDC93 CCDC93 REPS2 REPS2 VTA1 VTA1 ENSMLEP00000012429 ENSMLEP00000012429 ABCA1 ABCA1 ZFYVE9 ZFYVE9 MYO5B MYO5B RAB11B RAB11B GBF1 GBF1 ANKRD50 ANKRD50 LOC105546879 LOC105546879 CLTC CLTC SORT1 SORT1 LYST LYST TBC1D23 TBC1D23 ALMS1 ALMS1 TRIM27 TRIM27 GOLT1A GOLT1A TMCC1 TMCC1 SNX4 SNX4 ALS2CL ALS2CL RAB14 RAB14 ENSMLEP00000015485 ENSMLEP00000015485 ARHGAP1 ARHGAP1 EHD1 EHD1 AP3B1 AP3B1 SGSM2 SGSM2 SRL SRL VTI1B VTI1B SNX17 SNX17 VPS52 VPS52 MVB12B MVB12B WAS WAS SNX30 SNX30 CLTCL1 CLTCL1 ENSMLEP00000017328 ENSMLEP00000017328 RIC1 RIC1 SNX5 SNX5 VAMP4 VAMP4 EVI5 EVI5 CHMP4B CHMP4B LMTK2 LMTK2 DPY30 DPY30 SNX1 SNX1 AP5M1 AP5M1 VTI1A VTI1A TBC1D10A TBC1D10A RILP RILP EPG5 EPG5 CCDC22 CCDC22 ITSN2 ITSN2 YKT6 YKT6 RAB11FIP4 RAB11FIP4 RAB29 RAB29 ITSN1 ITSN1 RAB8B RAB8B CHMP2A CHMP2A SLC66A2 SLC66A2 WASHC3 WASHC3 ARFRP1 ARFRP1 ENSMLEP00000020206 ENSMLEP00000020206 VPS51 VPS51 MICALL1 MICALL1 VPS37B VPS37B RASSF9 RASSF9 RNF126 RNF126 SPAG9 SPAG9 LOC105544932 LOC105544932 MICALL2 MICALL2 VPS54 VPS54 UBE2O UBE2O EIPR1 EIPR1 VPS37A VPS37A ENTR1 ENTR1 ANKRD27 ANKRD27 VCP VCP SNX9 SNX9 TBC1D10B TBC1D10B ARL1 ARL1 VPS50 VPS50 ENSMLEP00000024238 ENSMLEP00000024238 BTBD8 BTBD8 MVB12A MVB12A VPS4A VPS4A TSG101 TSG101 SNX6 SNX6 SNX27 SNX27 EHD4 EHD4 STX6 STX6 LAMTOR1 LAMTOR1 WASHC4 WASHC4 VPS39 VPS39 LOC105531785 LOC105531785 LAPTM4B LAPTM4B SNF8 SNF8 DCTN1 DCTN1 GGA1 GGA1 ENSMLEP00000026981 ENSMLEP00000026981 VPS26C VPS26C WASHC1 WASHC1 RAB41 RAB41 PICALM PICALM VPS25 VPS25 ENSMLEP00000028984 ENSMLEP00000028984 ZFYVE16 ZFYVE16 STAM2 STAM2 AP5B1 AP5B1 ENSMLEP00000029371 ENSMLEP00000029371 TINAGL1 TINAGL1 UBXN6 UBXN6 DENND5A DENND5A RAB10 RAB10 RAB6B RAB6B ENSMLEP00000030691 ENSMLEP00000030691 SNX32 SNX32 CLEC16A CLEC16A LRRC1 LRRC1 AP5Z1 AP5Z1 DENND1C DENND1C LEPROTL1 LEPROTL1 LOC105537024 LOC105537024 DENND2A DENND2A RAB35 RAB35 NSG1 NSG1 SNX8 SNX8 RAB7A RAB7A TMEM87A TMEM87A GGA3 GGA3 NSG2 NSG2 VPS36 VPS36 RAB17 RAB17 RGP1 RGP1 STAM STAM RBSN RBSN RHOBTB3 RHOBTB3 GOLT1B GOLT1B RAB11FIP3 RAB11FIP3 LEPROT LEPROT RAB13 RAB13 KIAA1109 KIAA1109 ENSMLEP00000036399 ENSMLEP00000036399 ALS2 ALS2 VPS26B VPS26B TMEM87B TMEM87B CALY CALY TBC1D5 TBC1D5 STX5 STX5 ARHGAP44 ARHGAP44 DCLK1 DCLK1 CMTM6 CMTM6 DENND1B DENND1B CORO1C CORO1C BAIAP3 BAIAP3 TMEM50A TMEM50A REPS1 REPS1 GRIPAP1 GRIPAP1 SCRIB SCRIB TRARG1 TRARG1 DENND1A DENND1A STX10 STX10 ANKFY1 ANKFY1 PHETA1 PHETA1 SNX18 SNX18 VAMP3 VAMP3 TBC1D10C TBC1D10C PREPL PREPL ENSMLEP00000040242 ENSMLEP00000040242 CRACR2A CRACR2A ENSMLEP00000040343 ENSMLEP00000040343 AGAP2 AGAP2 EHD2 EHD2 VPS53 VPS53 RAB7B RAB7B CHMP4C CHMP4C VPS16 VPS16 LAPTM4A LAPTM4A LOC105547352 LOC105547352 MAGEL2 MAGEL2 RAB9A RAB9A TOM1 TOM1 ARF6 ARF6 TBC1D17 TBC1D17 GRIP1 GRIP1 SNX2 SNX2 VPS29 VPS29 HEATR5A HEATR5A GCC2 GCC2 EHD3 EHD3 TMEM50B TMEM50B PLEKHJ1 PLEKHJ1 EPS15 EPS15 AP5S1 AP5S1 DENND10 DENND10 ATP6AP1 ATP6AP1 SNX33 SNX33 TRAPPC10 TRAPPC10 SNX12 SNX12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARL4CADP ribosylation factor like GTPase 4C; Belongs to the small GTPase superfamily. Arf family. (202 aa)
ENSMLEP00000007799Uncharacterized protein. (200 aa)
ENSMLEP00000008672Uncharacterized protein. (141 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (664 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (815 aa)
VPS35LVPS35 endosomal protein sorting factor like. (1006 aa)
UBAP1Ubiquitin associated protein 1. (566 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1120 aa)
ACAP2ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. (768 aa)
VPS26AVPS26, retromer complex component A. (334 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1634 aa)
GRIP2Glutamate receptor interacting protein 2. (1143 aa)
AP3D1AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1181 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2070 aa)
STX16Syntaxin 16; Belongs to the syntaxin family. (325 aa)
TBC1D14TBC1 domain family member 14. (693 aa)
HEATR5BHEAT repeat containing 5B. (2071 aa)
CCDC93Coiled-coil domain containing 93. (631 aa)
REPS2RALBP1 associated Eps domain containing 2. (584 aa)
VTA1Vesicle trafficking 1. (307 aa)
ENSMLEP00000012429EH domain-containing protein. (100 aa)
ABCA1ATP binding cassette subfamily A member 1. (1919 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1425 aa)
MYO5BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1841 aa)
RAB11BUncharacterized protein. (448 aa)
GBF1Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1859 aa)
ANKRD50Ankyrin repeat domain 50. (1429 aa)
LOC105546879Uncharacterized protein. (2307 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
SORT1Sortilin. (676 aa)
LYSTUncharacterized protein. (1377 aa)
TBC1D23TBC1 domain family member 23. (699 aa)
ALMS1ALMS1 centrosome and basal body associated protein. (4174 aa)
TRIM27Tripartite motif containing 27. (513 aa)
GOLT1AGolgi transport 1A. (132 aa)
TMCC1Transmembrane and coiled-coil domain family 1. (461 aa)
SNX4Sorting nexin 4. (369 aa)
ALS2CLALS2 C-terminal like. (938 aa)
RAB14RAB14, member RAS oncogene family. (215 aa)
ENSMLEP00000015485Uncharacterized protein. (158 aa)
ARHGAP1Rho GTPase activating protein 1. (476 aa)
EHD1EH domain containing 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (548 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1087 aa)
SGSM2Small G protein signaling modulator 2. (1045 aa)
SRLSarcalumenin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (435 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
SNX17Sorting nexin 17. (475 aa)
VPS52VPS52 subunit of GARP complex. (723 aa)
MVB12BMultivesicular body subunit 12B. (194 aa)
WASWASP actin nucleation promoting factor. (503 aa)
SNX30Sorting nexin family member 30. (505 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1572 aa)
ENSMLEP00000017328Uncharacterized protein. (166 aa)
RIC1RIC1 homolog, RAB6A GEF complex partner 1. (1422 aa)
SNX5Sorting nexin; Involved in several stages of intracellular trafficking. (405 aa)
VAMP4Vesicle associated membrane protein 4. (141 aa)
EVI5Ecotropic viral integration site 5. (717 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
LMTK2Lemur tyrosine kinase 2. (1467 aa)
DPY30Dpy-30 histone methyltransferase complex regulatory subunit. (99 aa)
SNX1Sorting nexin 1. (557 aa)
AP5M1Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family. (490 aa)
VTI1AVesicle transport through interaction with t-SNAREs 1A. (217 aa)
TBC1D10ATBC1 domain family member 10A. (508 aa)
RILPRab interacting lysosomal protein. (253 aa)
EPG5Ectopic P-granules autophagy protein 5 homolog. (2557 aa)
CCDC22Coiled-coil domain containing 22. (627 aa)
ITSN2Intersectin 2. (1697 aa)
YKT6YKT6 v-SNARE homolog; Belongs to the synaptobrevin family. (163 aa)
RAB11FIP4RAB11 family interacting protein 4. (584 aa)
RAB29RAB29, member RAS oncogene family. (166 aa)
ITSN1Intersectin 1. (1719 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
SLC66A2Solute carrier family 66 member 2. (254 aa)
WASHC3WASH complex subunit 3. (194 aa)
ARFRP1ADP ribosylation factor related protein 1. (201 aa)
ENSMLEP00000020206Uncharacterized protein. (285 aa)
VPS51VPS51 subunit of GARP complex. (727 aa)
MICALL1MICAL like 1. (795 aa)
VPS37BVPS37B subunit of ESCRT-I. (285 aa)
RASSF9Ras association domain family member 9. (435 aa)
RNF126Ring finger protein 126. (310 aa)
SPAG9Sperm associated antigen 9. (1274 aa)
LOC105544932Uncharacterized protein. (164 aa)
MICALL2MICAL like 2. (834 aa)
VPS54VPS54 subunit of GARP complex. (977 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1099 aa)
EIPR1EARP complex and GARP complex interacting protein 1. (384 aa)
VPS37AVPS37A subunit of ESCRT-I. (397 aa)
ENTR1Endosome associated trafficking regulator 1. (388 aa)
ANKRD27Ankyrin repeat domain 27. (1033 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
SNX9Sorting nexin. (596 aa)
TBC1D10BTBC1 domain family member 10B. (728 aa)
ARL1ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family. (164 aa)
VPS50VPS50 subunit of EARP/GARPII complex. (964 aa)
ENSMLEP00000024238Uncharacterized protein. (135 aa)
BTBD8BTB domain containing 8. (1411 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (474 aa)
TSG101Tumor susceptibility 101. (390 aa)
SNX6Sorting nexin; Involved in several stages of intracellular trafficking. (407 aa)
SNX27Sorting nexin 27. (435 aa)
EHD4EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (462 aa)
STX6Syntaxin 6; Belongs to the syntaxin family. (255 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
WASHC4WASH complex subunit 4. (1174 aa)
VPS39VPS39 subunit of HOPS complex. (895 aa)
LOC105531785PX domain-containing protein. (206 aa)
LAPTM4BLysosomal protein transmembrane 4 beta. (301 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
DCTN1CAP-Gly domain-containing protein. (1278 aa)
GGA1Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (639 aa)
ENSMLEP00000026981PX domain-containing protein. (262 aa)
VPS26CVPS26 endosomal protein sorting factor C. (297 aa)
WASHC1WASH complex subunit 1. (467 aa)
RAB41RAB41, member RAS oncogene family. (223 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (674 aa)
VPS25Vacuolar protein sorting 25 homolog. (179 aa)
ENSMLEP00000028984Uncharacterized protein. (196 aa)
ZFYVE16Zinc finger FYVE-type containing 16. (1540 aa)
STAM2Signal transducing adaptor molecule 2. (525 aa)
AP5B1Adaptor related protein complex 5 subunit beta 1. (810 aa)
ENSMLEP00000029371Uncharacterized protein. (406 aa)
TINAGL1Tubulointerstitial nephritis antigen like 1; Belongs to the peptidase C1 family. (467 aa)
UBXN6UBX domain protein 6. (394 aa)
DENND5ADENN domain containing 5A. (1258 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
RAB6BRAB6B, member RAS oncogene family. (195 aa)
ENSMLEP00000030691Uncharacterized protein. (160 aa)
SNX32Sorting nexin; Involved in several stages of intracellular trafficking. (403 aa)
CLEC16AC-type lectin domain containing 16A. (1047 aa)
LRRC1Leucine rich repeat containing 1. (507 aa)
AP5Z1Adaptor related protein complex 5 subunit zeta 1. (775 aa)
DENND1CDENN domain containing 1C. (801 aa)
LEPROTL1Leptin receptor overlapping transcript like 1. (169 aa)
LOC105537024CAP-ZIP_m domain-containing protein. (1215 aa)
DENND2ADENN domain containing 2A. (989 aa)
RAB35RAB35, member RAS oncogene family. (319 aa)
NSG1Neuronal vesicle trafficking associated 1. (185 aa)
SNX8Sorting nexin 8. (452 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
TMEM87ATransmembrane protein 87A. (555 aa)
GGA3Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (723 aa)
NSG2Neuronal vesicle trafficking associated 2. (171 aa)
VPS36Vacuolar protein sorting 36 homolog. (232 aa)
RAB17RAB17, member RAS oncogene family. (212 aa)
RGP1RGP1 homolog, RAB6A GEF complex partner 1. (391 aa)
STAMSignal transducing adaptor molecule. (540 aa)
RBSNRabenosyn, RAB effector. (785 aa)
RHOBTB3Rho related BTB domain containing 3. (611 aa)
GOLT1BGolgi transport 1B. (138 aa)
RAB11FIP3RAB11 family interacting protein 3. (443 aa)
LEPROTLeptin receptor overlapping transcript. (139 aa)
RAB13Uncharacterized protein. (203 aa)
KIAA1109KIAA1109. (5005 aa)
ENSMLEP00000036399Uncharacterized protein. (95 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1657 aa)
VPS26BVPS26, retromer complex component B. (281 aa)
TMEM87BTransmembrane protein 87B. (556 aa)
CALYCalcyon neuron specific vesicular protein. (220 aa)
TBC1D5TBC1 domain family member 5. (819 aa)
STX5Syntaxin 5; Belongs to the syntaxin family. (361 aa)
ARHGAP44Rho GTPase activating protein 44. (818 aa)
DCLK1Doublecortin like kinase 1. (740 aa)
CMTM6MARVEL domain-containing protein. (183 aa)
DENND1BDENN domain containing 1B. (733 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (527 aa)
BAIAP3BAI1 associated protein 3. (1187 aa)
TMEM50ATransmembrane protein 50A. (157 aa)
REPS1RALBP1 associated Eps domain containing 1. (796 aa)
GRIPAP1GRIP1 associated protein 1. (841 aa)
SCRIBScribble planar cell polarity protein. (1445 aa)
TRARG1Trafficking regulator of GLUT4 (SLC2A4) 1. (177 aa)
DENND1ADENN domain containing 1A. (1007 aa)
STX10Syntaxin 10; Belongs to the syntaxin family. (249 aa)
ANKFY1Ankyrin repeat and FYVE domain containing 1. (1158 aa)
PHETA1PH domain containing endocytic trafficking adaptor 1. (159 aa)
SNX18Sorting nexin 18. (415 aa)
VAMP3Vesicle associated membrane protein 3. (181 aa)
TBC1D10CTBC1 domain family member 10C. (446 aa)
PREPLProlyl endopeptidase like. (727 aa)
ENSMLEP00000040242Uncharacterized protein. (237 aa)
CRACR2ACalcium release activated channel regulator 2A. (732 aa)
ENSMLEP00000040343Uncharacterized protein; Belongs to the synaptobrevin family. (204 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (756 aa)
EHD2EH domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (529 aa)
VPS53VPS53 subunit of GARP complex. (830 aa)
RAB7BRAB7B, member RAS oncogene family. (199 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa)
LAPTM4ALysosomal protein transmembrane 4 alpha. (233 aa)
LOC105547352Annexin. (352 aa)
MAGEL2MAGE family member L2. (1253 aa)
RAB9ARAB9A, member RAS oncogene family. (201 aa)
TOM1Target of myb1 membrane trafficking protein; Belongs to the TOM1 family. (489 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
TBC1D17TBC1 domain family member 17. (648 aa)
GRIP1Glutamate receptor interacting protein 1. (1128 aa)
SNX2Sorting nexin 2. (402 aa)
VPS29Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (214 aa)
HEATR5AHEAT repeat containing 5A. (2006 aa)
GCC2GRIP and coiled-coil domain containing 2. (1671 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
TMEM50BUncharacterized protein. (161 aa)
PLEKHJ1PH domain-containing protein. (144 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (859 aa)
AP5S1Adaptor related protein complex 5 subunit sigma 1. (200 aa)
DENND10DENN domain containing 10. (340 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (470 aa)
SNX33Sorting nexin. (574 aa)
TRAPPC10Uncharacterized protein. (1219 aa)
SNX12Sorting nexin 12. (174 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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