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POLR2C POLR2C ATXN7L3 ATXN7L3 TAF9B TAF9B ENSMLEP00000014695 ENSMLEP00000014695 ENSMLEP00000014379 ENSMLEP00000014379 CCNH CCNH ENY2-2 ENY2-2 POLR2A POLR2A GTF2A1L GTF2A1L TAF4B TAF4B ENSMLEP00000012032 ENSMLEP00000012032 GTF2A1 GTF2A1 LOC105543372 LOC105543372 TAF12 TAF12 TAF5 TAF5 TCEA1 TCEA1 GTF2E1 GTF2E1 RPRD2 RPRD2 LOC105553920 LOC105553920 ENSMLEP00000007973 ENSMLEP00000007973 LOC105529834 LOC105529834 GTF2F1 GTF2F1 ENSMLEP00000006620 ENSMLEP00000006620 CTR9 CTR9 TAF11 TAF11 TRRAP TRRAP TAF1L TAF1L LOC105539645 LOC105539645 TBP TBP GTF2F2 GTF2F2 RTF1 RTF1 ENSMLEP00000002991 ENSMLEP00000002991 POLR2E POLR2E PEX2 PEX2 TAF6 TAF6 TAF10 TAF10 RPAP2 RPAP2 ENSMLEP00000020954 ENSMLEP00000020954 TAF1 TAF1 MNAT1 MNAT1 CDC73 CDC73 WDR61 WDR61 POLR2D POLR2D TAF7L TAF7L SETD5 SETD5 ATXN7 ATXN7 ENSMLEP00000026138 ENSMLEP00000026138 TAF3 TAF3 GTF2A2 GTF2A2 GTF2H3 GTF2H3 TADA3 TADA3 TAF2 TAF2 ENY2 ENY2 POLR2K POLR2K SUPT3H SUPT3H TAF8 TAF8 KAT2A KAT2A POLR2B POLR2B TAF13 TAF13 POLR2I POLR2I POLR2H POLR2H TBPL1 TBPL1 MYO6 MYO6 TAF5L TAF5L TAF4 TAF4 ENSMLEP00000035771 ENSMLEP00000035771 ENSMLEP00000035797 ENSMLEP00000035797 GTF2H1 GTF2H1 PAF1 PAF1 GTF2H4 GTF2H4 ENY2-3 ENY2-3 LEO1 LEO1 ERCC2 ERCC2 RPRD1B RPRD1B MMS19 MMS19 GTF2E2 GTF2E2 POLR2G POLR2G GTF2H5 GTF2H5 TAF6L TAF6L POLR2F POLR2F RECQL5 RECQL5 POLR2J POLR2J LOC105548148 LOC105548148 CDK7 CDK7 RPRD1A RPRD1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2CRNA polymerase II subunit C. (275 aa)
ATXN7L3Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa)
TAF9BTATA-box binding protein associated factor 9b. (251 aa)
ENSMLEP00000014695TAFII28 domain-containing protein. (195 aa)
ENSMLEP00000014379Uncharacterized protein. (297 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
ENY2-2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (97 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1936 aa)
GTF2A1LGeneral transcription factor IIA subunit 1 like. (448 aa)
TAF4BTATA-box binding protein associated factor 4b. (867 aa)
ENSMLEP00000012032Uncharacterized protein. (54 aa)
GTF2A1General transcription factor IIA subunit 1. (370 aa)
LOC105543372General transcription factor IIH subunit. (380 aa)
TAF12TATA-box binding protein associated factor 12. (213 aa)
TAF5TATA-box binding protein associated factor 5. (656 aa)
TCEA1Transcription elongation factor A1. (301 aa)
GTF2E1General transcription factor IIE subunit 1. (439 aa)
RPRD2Regulation of nuclear pre-mRNA domain containing 2. (1461 aa)
LOC105553920BSD domain-containing protein. (430 aa)
ENSMLEP00000007973TAFII28 domain-containing protein. (205 aa)
LOC105529834Uncharacterized protein. (270 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (545 aa)
ENSMLEP00000006620Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (104 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
TAF11TATA-box binding protein associated factor 11. (211 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3846 aa)
TAF1LTranscription initiation factor TFIID subunit. (1884 aa)
LOC105539645Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (192 aa)
TBPTATA-box binding protein. (328 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (575 aa)
ENSMLEP00000002991Uncharacterized protein. (68 aa)
POLR2ERNA polymerase II subunit E. (176 aa)
PEX2Peroxisomal biogenesis factor 2. (305 aa)
TAF6TATA-box binding protein associated factor 6. (738 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
RPAP2RNA polymerase II associated protein 2. (612 aa)
ENSMLEP00000020954TFIID_NTD2 domain-containing protein. (300 aa)
TAF1Transcription initiation factor TFIID subunit. (1881 aa)
MNAT1MNAT1 component of CDK activating kinase. (234 aa)
CDC73Cell division cycle 73. (531 aa)
WDR61WD repeat domain 61. (305 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
TAF7LTATA-box binding protein associated factor 7 like. (464 aa)
SETD5SET domain containing 5. (1461 aa)
ATXN7SCA7 domain-containing protein. (846 aa)
ENSMLEP00000026138TFIIA_gamma_C domain-containing protein. (75 aa)
TAF3TATA-box binding protein associated factor 3. (868 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
GTF2H3General transcription factor IIH subunit 3. (308 aa)
TADA3Transcriptional adaptor 3. (440 aa)
TAF2TATA-box binding protein associated factor 2. (1152 aa)
ENY2Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
SUPT3HSPT3 homolog, SAGA and STAGA complex component. (328 aa)
TAF8TATA-box binding protein associated factor 8. (338 aa)
KAT2ALysine acetyltransferase 2A. (755 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1167 aa)
TAF13Uncharacterized protein. (86 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
TBPL1TATA-box binding protein like 1. (186 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1290 aa)
TAF5LTATA-box binding protein associated factor 5 like. (589 aa)
TAF4TATA-box binding protein associated factor 4. (635 aa)
ENSMLEP00000035771Uncharacterized protein. (68 aa)
ENSMLEP00000035797Uncharacterized protein. (235 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
ENY2-3Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (91 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
RPRD1BRegulation of nuclear pre-mRNA domain containing 1B. (326 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
TAF6LTATA-box binding protein associated factor 6 like. (622 aa)
POLR2FRNA polymerase II subunit F. (158 aa)
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (159 aa)
LOC105548148Protein kinase domain-containing protein. (312 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
RPRD1ARegulation of nuclear pre-mRNA domain containing 1A. (315 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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