(69 nodes) SCF ubiquitin ligase complex network (Mandrillus leucophaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105538609	F-box domain-containing protein. (238 aa)
	FBXL20	F-box and leucine rich repeat protein 20. (438 aa)
	FBXW5	F-box and WD repeat domain containing 5. (457 aa)
	SPSB2	SplA/ryanodine receptor domain and SOCS box containing 2. (250 aa)
	FBXL22	F-box and leucine rich repeat protein 22. (205 aa)
	FBXL14	F-box and leucine rich repeat protein 14. (418 aa)
	LOC105552134	Uncharacterized protein. (228 aa)
	FBXO2	F-box protein 2. (297 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa)
	ENSMLEP00000008311	Uncharacterized protein; Belongs to the SKP1 family. (142 aa)
	FBXW8	F-box and WD repeat domain containing 8. (492 aa)
	FBXL16	F-box and leucine rich repeat protein 16. (416 aa)
	FBXO48	F-box protein 48. (155 aa)
	LOC105528799	Uncharacterized protein. (199 aa)
	FBXO33	F-box protein 33. (555 aa)
	USP47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
	CKS1B	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	FBXO25	F-box protein 25. (367 aa)
	FBXL15	F-box and leucine rich repeat protein 15. (300 aa)
	FBXO32	F-box protein 32. (355 aa)
	ENSMLEP00000017044	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (86 aa)
	SPSB3	SplA/ryanodine receptor domain and SOCS box containing 3. (355 aa)
	FBXL21P	F-box domain-containing protein. (434 aa)
	CCNF	Cyclin F; Belongs to the cyclin family. (786 aa)
	LOC105545975	Uncharacterized protein. (448 aa)
	FBXO7	F-box protein 7. (443 aa)
	FBXO4	F-box protein 4. (324 aa)
	FBXO17	F-box protein 17. (278 aa)
	LOC105529932	Uncharacterized protein. (84 aa)
	FBXO39	F-box protein 39. (442 aa)
	FBXW11	F-box and WD repeat domain containing 11. (546 aa)
	FBH1	F-box DNA helicase 1. (1044 aa)
	FBXW7	F-box and WD repeat domain containing 7. (707 aa)
	ENSMLEP00000022706	Zf-rbx1 domain-containing protein. (93 aa)
	CKS2	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa)
	FBXL5	F-box and leucine rich repeat protein 5. (673 aa)
	ENSMLEP00000023372	Siah-Interact_N domain-containing protein. (80 aa)
	FBXL8	F-box domain-containing protein. (375 aa)
	SKP2	S-phase kinase associated protein 2. (424 aa)
	FBXL2	F-box and leucine rich repeat protein 2. (425 aa)
	FBXL7	F-box and leucine rich repeat protein 7. (491 aa)
	ENSMLEP00000025412	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (69 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	SPSB4	SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)
	FBXL13	F-box and leucine rich repeat protein 13. (735 aa)
	GSE1	Gse1 coiled-coil protein. (1326 aa)
	FBXL3	F-box and leucine rich repeat protein 3. (428 aa)
	FBXO27	F-box protein 27. (285 aa)
	FBXL6	Uncharacterized protein. (300 aa)
	FBXW4	F-box and WD repeat domain containing 4. (325 aa)
	FBXO42	F-box protein 42. (716 aa)
	FBXO15	F-box protein 15. (434 aa)
	LRRC29	Leucine rich repeat containing 29. (214 aa)
	FBXO6	F-box protein 6. (293 aa)
	AMN1	Antagonist of mitotic exit network 1 homolog. (258 aa)
	FBXL19	F-box and leucine rich repeat protein 19. (694 aa)
	SPSB1	SplA/ryanodine receptor domain and SOCS box containing 1. (250 aa)
	LOC105534809	Uncharacterized protein. (300 aa)
	FBXO44	Uncharacterized protein. (255 aa)
	FBXO31	F-box protein 31. (367 aa)
	LOC105537381	Uncharacterized protein. (335 aa)
	FBXL12	F-box and leucine rich repeat protein 12. (326 aa)
	FBXO45	F-box protein 45. (253 aa)
	ENSMLEP00000038171	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (66 aa)
	ENSMLEP00000039257	Uncharacterized protein. (300 aa)
	FBXO9	F-box protein 9. (437 aa)
	FBXO38	F-box protein 38. (1113 aa)
	RBX1	RING-type domain-containing protein. (108 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMN1	CUL1	ENSMLEP00000032264	ENSMLEP00000040837	Antagonist of mitotic exit network 1 homolog.	Cullin 1; Belongs to the cullin family.	0.488
AMN1	ENSMLEP00000008311	ENSMLEP00000032264	ENSMLEP00000008311	Antagonist of mitotic exit network 1 homolog.	Uncharacterized protein; Belongs to the SKP1 family.	0.576
AMN1	ENSMLEP00000022706	ENSMLEP00000032264	ENSMLEP00000022706	Antagonist of mitotic exit network 1 homolog.	Zf-rbx1 domain-containing protein.	0.444
AMN1	RBX1	ENSMLEP00000032264	ENSMLEP00000040271	Antagonist of mitotic exit network 1 homolog.	RING-type domain-containing protein.	0.444
AMN1	SKP1	ENSMLEP00000032264	ENSMLEP00000007997	Antagonist of mitotic exit network 1 homolog.	S-phase kinase associated protein 1; Belongs to the SKP1 family.	0.576
BTRC	CCNF	ENSMLEP00000026137	ENSMLEP00000018727	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cyclin F; Belongs to the cyclin family.	0.503
BTRC	CUL1	ENSMLEP00000026137	ENSMLEP00000040837	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Cullin 1; Belongs to the cullin family.	0.996
BTRC	ENSMLEP00000008311	ENSMLEP00000026137	ENSMLEP00000008311	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein; Belongs to the SKP1 family.	0.990
BTRC	ENSMLEP00000022706	ENSMLEP00000026137	ENSMLEP00000022706	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Zf-rbx1 domain-containing protein.	0.955
BTRC	FBXL3	ENSMLEP00000026137	ENSMLEP00000027652	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and leucine rich repeat protein 3.	0.421
BTRC	FBXO2	ENSMLEP00000026137	ENSMLEP00000005507	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 2.	0.929
BTRC	FBXO4	ENSMLEP00000026137	ENSMLEP00000020508	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 4.	0.904
BTRC	FBXO44	ENSMLEP00000026137	ENSMLEP00000035696	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein.	0.447
BTRC	FBXO6	ENSMLEP00000026137	ENSMLEP00000031816	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box protein 6.	0.581
BTRC	FBXW11	ENSMLEP00000026137	ENSMLEP00000021972	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 11.	0.959
BTRC	FBXW7	ENSMLEP00000026137	ENSMLEP00000022623	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 7.	0.937
BTRC	FBXW8	ENSMLEP00000026137	ENSMLEP00000009969	Beta-transducin repeat containing E3 ubiquitin protein ligase.	F-box and WD repeat domain containing 8.	0.461
BTRC	LOC105545975	ENSMLEP00000026137	ENSMLEP00000019466	Beta-transducin repeat containing E3 ubiquitin protein ligase.	Uncharacterized protein.	0.960
BTRC	RBX1	ENSMLEP00000026137	ENSMLEP00000040271	Beta-transducin repeat containing E3 ubiquitin protein ligase.	RING-type domain-containing protein.	0.988
BTRC	SKP1	ENSMLEP00000026137	ENSMLEP00000007997	Beta-transducin repeat containing E3 ubiquitin protein ligase.	S-phase kinase associated protein 1; Belongs to the SKP1 family.	0.990