STRINGSTRING
TBL2 TBL2 BHLHA15 BHLHA15 EIF2AK3 EIF2AK3 CREB3 CREB3 OS9 OS9 ERO1A ERO1A RHBDD2 RHBDD2 ATF3 ATF3 ATF4 ATF4 VAPB VAPB DERL1 DERL1 CREB3L1 CREB3L1 WFS1 WFS1 CREB3L2 CREB3L2 AMFR AMFR NFE2L2 NFE2L2 EIF2S1 EIF2S1 DERL2 DERL2 HERPUD2 HERPUD2 ENSMLEP00000033047 ENSMLEP00000033047 ERN2 ERN2 EP300 EP300 XBP1 XBP1 SELENOS SELENOS FGF21 FGF21 DERL3 DERL3 STUB1 STUB1 VCP VCP HSPA5 HSPA5 MBTPS1 MBTPS1 ENSMLEP00000022361 ENSMLEP00000022361 PARP16 PARP16 TMTC4 TMTC4 DDIT3 DDIT3 CDK5RAP3 CDK5RAP3 ATF6B ATF6B ERN1 ERN1 EIF2AK2 EIF2AK2 ERMP1 ERMP1 CASP12 CASP12 ENSMLEP00000014973 ENSMLEP00000014973 CREB3L4 CREB3L4 ATF6 ATF6 QRICH1 QRICH1 ERLEC1 ERLEC1 LOC105543880 LOC105543880 TMED2 TMED2 YOD1 YOD1 PTPN1 PTPN1 CREB3L3 CREB3L3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBL2Transducin beta like 2. (446 aa)
BHLHA15Basic helix-loop-helix family member a15. (191 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1012 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
OS9OS9 endoplasmic reticulum lectin. (716 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (451 aa)
RHBDD2Rhomboid domain containing 2. (364 aa)
ATF3Activating transcription factor 3. (181 aa)
ATF4Activating transcription factor 4. (351 aa)
VAPBVAMP associated protein B and C. (138 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (466 aa)
WFS1Wolframin ER transmembrane glycoprotein. (890 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
AMFRAutocrine motility factor receptor. (558 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (596 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
HERPUD2HERPUD family member 2. (406 aa)
ENSMLEP00000033047Uncharacterized protein. (67 aa)
ERN2Endoplasmic reticulum to nucleus signaling 2. (821 aa)
EP300E1A binding protein p300. (2411 aa)
XBP1X-box binding protein 1. (204 aa)
SELENOSSelenoprotein S. (211 aa)
FGF21Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family. (174 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (238 aa)
STUB1STIP1 homology and U-box containing protein 1. (250 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
MBTPS1Membrane bound transcription factor peptidase, site 1. (1052 aa)
ENSMLEP00000022361Uncharacterized protein; Belongs to the heat shock protein 70 family. (580 aa)
PARP16Poly [ADP-ribose] polymerase. (301 aa)
TMTC4Transmembrane O-mannosyltransferase targeting cadherins 4. (764 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (519 aa)
ATF6BActivating transcription factor 6 beta. (711 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (959 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (551 aa)
ERMP1Endoplasmic reticulum metallopeptidase 1. (791 aa)
CASP12Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (421 aa)
ENSMLEP00000014973MSP domain-containing protein. (91 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (422 aa)
ATF6Activating transcription factor 6. (669 aa)
QRICH1Glutamine rich 1. (777 aa)
ERLEC1Endoplasmic reticulum lectin 1. (483 aa)
LOC105543880GOLD domain-containing protein. (188 aa)
TMED2Transmembrane p24 trafficking protein 2. (116 aa)
YOD1YOD1 deubiquitinase. (348 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (321 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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