40 items (Mandrillus leucophaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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	CPSF1	Cleavage and polyadenylation specific factor 1. (1460 aa)
	PABPC1L	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (614 aa)
	AHCYL1	Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (509 aa)
	LEO1	LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
	CLP1	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (436 aa)
	MTPAP	Mitochondrial poly(A) polymerase. (582 aa)
	RPRD1B	Regulation of nuclear pre-mRNA domain containing 1B. (326 aa)
	CPSF4L	Cleavage and polyadenylation specific factor 4 like. (179 aa)
	ZC3H3	Zinc finger CCCH-type containing 3. (950 aa)
	WDR33	WD repeat domain 33. (1336 aa)
	CSTF2	Cleavage stimulation factor subunit 2. (597 aa)
	POLR2D	RNA polymerase II subunit D. (142 aa)
	CDC73	Cell division cycle 73. (531 aa)
	CPSF4	Cleavage and polyadenylation specific factor 4. (269 aa)
	TENT4B	Terminal nucleotidyltransferase 4B. (573 aa)
	PAPOLA	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
	CPSF7	Cleavage and polyadenylation specific factor 7. (489 aa)
	NCBP1	Nuclear cap binding protein subunit 1. (790 aa)
	CPSF2	Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
	LOC105551542	S1 motif domain-containing protein. (650 aa)
	RPRD2	Regulation of nuclear pre-mRNA domain containing 2. (1461 aa)
	LSM11	LSM11, U7 small nuclear RNA associated. (210 aa)
	CPSF3	Cleavage and polyadenylation specific factor 3. (684 aa)
	LSM10	LSM10, U7 small nuclear RNA associated. (123 aa)
	SLBP	Stem-loop binding protein. (257 aa)
	PCF11	PCF11 cleavage and polyadenylation factor subunit. (1555 aa)
	CSTF1	Cleavage stimulation factor subunit 1. (431 aa)
	TENT2	Terminal nucleotidyltransferase 2. (478 aa)
	GRSF1	G-rich RNA sequence binding factor 1. (362 aa)
	CPSF6	Cleavage and polyadenylation specific factor 6. (568 aa)
	PNPT1	Polyribonucleotide nucleotidyltransferase 1. (758 aa)
	PAPOLG	Poly(A) polymerase gamma. (736 aa)
	CSTF3	Cleavage stimulation factor subunit 3. (717 aa)
	APP	Amyloid beta precursor protein. (772 aa)
	APLP1	Amyloid beta precursor like protein 1. (657 aa)
	TUT1	RRM domain-containing protein. (908 aa)
	SYMPK	Symplekin. (1304 aa)
	NUDT21	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
	PAF1	PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa)
	ZNF473	Zinc finger protein 473. (871 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHCYL1	LOC105551542	ENSMLEP00000038330	ENSMLEP00000008935	Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family.	S1 motif domain-containing protein.	0.454
AHCYL1	PNPT1	ENSMLEP00000038330	ENSMLEP00000029076	Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family.	Polyribonucleotide nucleotidyltransferase 1.	0.454
CDC73	CPSF3	ENSMLEP00000022208	ENSMLEP00000006546	Cell division cycle 73.	Cleavage and polyadenylation specific factor 3.	0.458
CDC73	LEO1	ENSMLEP00000022208	ENSMLEP00000039014	Cell division cycle 73.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.999
CDC73	NCBP1	ENSMLEP00000022208	ENSMLEP00000012536	Cell division cycle 73.	Nuclear cap binding protein subunit 1.	0.523
CDC73	PAF1	ENSMLEP00000022208	ENSMLEP00000036710	Cell division cycle 73.	PAF1 homolog, Paf1/RNA polymerase II complex component.	0.998
CDC73	POLR2D	ENSMLEP00000022208	ENSMLEP00000023262	Cell division cycle 73.	RNA polymerase II subunit D.	0.900
CDC73	SYMPK	ENSMLEP00000022208	ENSMLEP00000032963	Cell division cycle 73.	Symplekin.	0.577
CLP1	CPSF1	ENSMLEP00000039044	ENSMLEP00000037938	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	Cleavage and polyadenylation specific factor 1.	0.952
CLP1	CPSF2	ENSMLEP00000039044	ENSMLEP00000010418	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	Cleavage and polyadenylation specificity factor subunit 2.	0.935
CLP1	CPSF3	ENSMLEP00000039044	ENSMLEP00000006546	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	Cleavage and polyadenylation specific factor 3.	0.950
CLP1	CPSF4	ENSMLEP00000039044	ENSMLEP00000021105	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	Cleavage and polyadenylation specific factor 4.	0.925
CLP1	CPSF4L	ENSMLEP00000039044	ENSMLEP00000028599	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	Cleavage and polyadenylation specific factor 4 like.	0.888
CLP1	CPSF6	ENSMLEP00000039044	ENSMLEP00000001061	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	Cleavage and polyadenylation specific factor 6.	0.831
CLP1	CPSF7	ENSMLEP00000039044	ENSMLEP00000014240	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	Cleavage and polyadenylation specific factor 7.	0.779
CLP1	CSTF1	ENSMLEP00000039044	ENSMLEP00000003694	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	Cleavage stimulation factor subunit 1.	0.889
CLP1	CSTF2	ENSMLEP00000039044	ENSMLEP00000025376	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	Cleavage stimulation factor subunit 2.	0.992
CLP1	CSTF3	ENSMLEP00000039044	ENSMLEP00000030869	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	Cleavage stimulation factor subunit 3.	0.965
CLP1	NCBP1	ENSMLEP00000039044	ENSMLEP00000012536	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	Nuclear cap binding protein subunit 1.	0.740
CLP1	NUDT21	ENSMLEP00000039044	ENSMLEP00000034710	Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]	Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	0.895