STRINGSTRING
MLST8 MLST8 RRAGD RRAGD RRAGB RRAGB ENSMLEP00000002412 ENSMLEP00000002412 LIN28A LIN28A LAMTOR2 LAMTOR2 RRAGA RRAGA WDR59 WDR59 GOLPH3 GOLPH3 PIP4P1 PIP4P1 GPR137 GPR137 RHEB RHEB GPR137B GPR137B FLCN FLCN SEC13 SEC13 PIK3CA PIK3CA KLHL22 KLHL22 SLC38A9 SLC38A9 LAMTOR3 LAMTOR3 GAS6 GAS6 TELO2 TELO2 RICTOR RICTOR LAMTOR1 LAMTOR1 SEH1L SEH1L GPR137C GPR137C WAC WAC MIOS MIOS HDAC3 HDAC3 LAMTOR4 LAMTOR4 CTNS CTNS TREM2 TREM2 SMCR8 SMCR8 XBP1 XBP1 CLEC16A CLEC16A SIK3 SIK3 RPTOR RPTOR FNIP1 FNIP1 WDR24 WDR24 HTR6 HTR6 RRAGC RRAGC OTUD5 OTUD5 LEP LEP PIH1D1 PIH1D1 LAMTOR5 LAMTOR5 AKT3 AKT3 NCKAP1L NCKAP1L RELN RELN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MLST8MTOR associated protein, LST8 homolog. (335 aa)
RRAGDRas related GTP binding D. (400 aa)
RRAGBRas related GTP binding B. (374 aa)
ENSMLEP00000002412Uncharacterized protein. (188 aa)
LIN28ALin-28 homolog A. (209 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (177 aa)
RRAGARas related GTP binding A. (313 aa)
WDR59WD repeat domain 59. (974 aa)
GOLPH3Golgi phosphoprotein 3. (232 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa)
GPR137G protein-coupled receptor 137. (432 aa)
RHEBRas homolog, mTORC1 binding. (181 aa)
GPR137BG protein-coupled receptor 137B. (344 aa)
FLCNFolliculin. (515 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KLHL22Kelch like family member 22. (634 aa)
SLC38A9Solute carrier family 38 member 9. (561 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
GAS6Growth arrest specific 6. (640 aa)
TELO2Telomere maintenance 2. (837 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1699 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (367 aa)
GPR137CG protein-coupled receptor 137C. (384 aa)
WACWW domain containing adaptor with coiled-coil. (633 aa)
MIOSMeiosis regulator for oocyte development. (875 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (112 aa)
CTNSCystinosin, lysosomal cystine transporter. (393 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (231 aa)
SMCR8SMCR8-C9orf72 complex subunit. (936 aa)
XBP1X-box binding protein 1. (204 aa)
CLEC16AC-type lectin domain containing 16A. (1047 aa)
SIK3SIK family kinase 3. (1296 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1291 aa)
FNIP1Folliculin interacting protein 1. (1166 aa)
WDR24WD repeat domain 24. (895 aa)
HTR65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (414 aa)
RRAGCRas related GTP binding C. (320 aa)
OTUD5OTU deubiquitinase 5. (434 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
PIH1D1PIH1 domain containing 1. (290 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (169 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
NCKAP1LNCK associated protein 1 like. (1056 aa)
RELNReelin. (3480 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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