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PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
BAIAP2 | BAI1 associated protein 2. (490 aa) | ||||
ENSMLEP00000009841 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (310 aa) | ||||
IRS1 | Insulin receptor substrate 1. (1242 aa) | ||||
INSRR | Tyrosine-protein kinase receptor. (1301 aa) | ||||
SLC2A4 | Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa) | ||||
SLC27A1 | Solute carrier family 27 member 1. (626 aa) | ||||
OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) | ||||
PDPK1 | 3-phosphoinositide dependent protein kinase 1. (529 aa) | ||||
SRSF5 | Serine and arginine rich splicing factor 5. (272 aa) | ||||
EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) | ||||
ENSMLEP00000013040 | Uncharacterized protein. (131 aa) | ||||
POTEA | POTE ankyrin domain family member A. (526 aa) | ||||
GHSR | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa) | ||||
TNFSF10 | Tumor necrosis factor ligand superfamily member. (281 aa) | ||||
FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) | ||||
ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. (845 aa) | ||||
CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa) | ||||
HSD11B2 | Hydroxysteroid 11-beta dehydrogenase 2. (387 aa) | ||||
SRSF6 | Serine and arginine rich splicing factor 6. (214 aa) | ||||
GRB14 | Growth factor receptor bound protein 14. (491 aa) | ||||
NCOA5 | Nuclear receptor coactivator 5. (579 aa) | ||||
SRSF4 | Serine and arginine rich splicing factor 4. (494 aa) | ||||
RPE65 | Retinoid isomerohydrolase RPE65. (533 aa) | ||||
KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (778 aa) | ||||
CSRP3 | Cysteine and glycine rich protein 3. (194 aa) | ||||
ENSMLEP00000015404 | Fork-head domain-containing protein. (531 aa) | ||||
IGFBP1 | Insulin like growth factor binding protein 1. (260 aa) | ||||
PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa) | ||||
GAB1 | GRB2 associated binding protein 1. (724 aa) | ||||
SLC25A33 | Solute carrier family 25 member 33; Belongs to the mitochondrial carrier (TC 2.A.29) family. (321 aa) | ||||
LOC105530298 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (679 aa) | ||||
EEF2K | Eukaryotic elongation factor 2 kinase. (725 aa) | ||||
EPRS1 | Glutamyl-prolyl-tRNA synthetase. (1487 aa) | ||||
ENSMLEP00000017280 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (149 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1301 aa) | ||||
OTOP1 | Otopetrin 1. (610 aa) | ||||
GRB2 | Growth factor receptor bound protein 2. (217 aa) | ||||
GHRHR | Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa) | ||||
SYAP1 | Synapse associated protein 1. (350 aa) | ||||
SLC27A4 | Solute carrier family 27 member 4. (651 aa) | ||||
ADIPOQ | Adiponectin, C1Q and collagen domain containing. (249 aa) | ||||
PTPRA | Receptor-type tyrosine-protein phosphatase alpha. (805 aa) | ||||
PRKDC | Protein kinase, DNA-activated, catalytic subunit. (3556 aa) | ||||
CAPN10 | Calpain 10; Belongs to the peptidase C2 family. (672 aa) | ||||
GAL | Galanin and GMAP prepropeptide. (131 aa) | ||||
SLC29A2 | Solute carrier family 29 member 2. (451 aa) | ||||
ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa) | ||||
EIF4EBP2 | Eukaryotic translation initiation factor 4E binding protein 2. (71 aa) | ||||
PPARA | Peroxisome proliferator activated receptor alpha. (365 aa) | ||||
RB1 | RB transcriptional corepressor 1. (891 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
HDAC9 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa) | ||||
ENSMLEP00000022796 | Uncharacterized protein. (111 aa) | ||||
LPIN3 | Lipin 3. (852 aa) | ||||
AGRP | Agouti related neuropeptide. (132 aa) | ||||
TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa) | ||||
IGF1R | Tyrosine-protein kinase receptor. (1281 aa) | ||||
BCAR3 | BCAR3 adaptor protein, NSP family member. (825 aa) | ||||
SESN2 | Sestrin 2. (450 aa) | ||||
FOXC2 | Forkhead box C2. (254 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa) | ||||
CCDC144NL | Uncharacterized protein. (1413 aa) | ||||
EGR2 | Early growth response 2. (476 aa) | ||||
SORBS1 | Sorbin and SH3 domain containing 1. (1294 aa) | ||||
TSC1 | TSC complex subunit 1. (1162 aa) | ||||
VPS13C | Vacuolar protein sorting 13 homolog C. (3754 aa) | ||||
KLF15 | Kruppel like factor 15. (416 aa) | ||||
LPIN1 | Lipin 1. (974 aa) | ||||
PHIP | Pleckstrin homology domain interacting protein. (1771 aa) | ||||
PDK4 | Protein-serine/threonine kinase. (411 aa) | ||||
ENSMLEP00000025945 | Uncharacterized protein. (137 aa) | ||||
MYO5A | Myosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1846 aa) | ||||
CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) | ||||
ANKRD26 | Ankyrin repeat domain 26. (1694 aa) | ||||
RETN | Resistin. (108 aa) | ||||
RAB15 | RAB15, member RAS oncogene family. (257 aa) | ||||
ENSMLEP00000027728 | Uncharacterized protein. (105 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase. (432 aa) | ||||
DNAI1 | Dynein axonemal intermediate chain 1. (704 aa) | ||||
CRY1 | Cryptochrome circadian regulator 1. (586 aa) | ||||
KBTBD2 | Kelch repeat and BTB domain containing 2. (623 aa) | ||||
INPP5K | Inositol polyphosphate-5-phosphatase K. (448 aa) | ||||
GPT | Glutamic--pyruvic transaminase. (496 aa) | ||||
USF1 | Upstream transcription factor 1. (310 aa) | ||||
SOGA1 | Suppressor of glucose, autophagy associated 1. (1474 aa) | ||||
ENSMLEP00000028984 | Uncharacterized protein. (196 aa) | ||||
PTPN2 | Tyrosine-protein phosphatase non-receptor type. (403 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (758 aa) | ||||
SELENOS | Selenoprotein S. (211 aa) | ||||
HMGCS2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa) | ||||
TBC1D4 | TBC1 domain family member 4. (1132 aa) | ||||
RAB10 | RAB10, member RAS oncogene family. (200 aa) | ||||
XBP1 | X-box binding protein 1. (204 aa) | ||||
GCK | Phosphotransferase. (466 aa) | ||||
PIK3R3 | Phosphoinositide-3-kinase regulatory subunit 3. (461 aa) | ||||
PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (583 aa) | ||||
SREBF1 | Sterol regulatory element binding transcription factor 1. (1124 aa) | ||||
LOC105548563 | Uncharacterized protein. (245 aa) | ||||
RAB31 | RAB31, member RAS oncogene family. (259 aa) | ||||
LPIN2 | Lipin 2. (896 aa) | ||||
PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa) | ||||
PRLH | Prolactin releasing hormone. (87 aa) | ||||
FOXO4 | Forkhead box O4. (505 aa) | ||||
ZNF106 | Zinc finger protein 106. (1883 aa) | ||||
C2CD5 | C2 calcium dependent domain containing 5. (1084 aa) | ||||
KL | Klotho; Belongs to the glycosyl hydrolase 1 family. (645 aa) | ||||
RAB8A | RAB8A, member RAS oncogene family. (207 aa) | ||||
ZBTB7B | Zinc finger and BTB domain containing 7B. (573 aa) | ||||
IDE | Insulin degrading enzyme; Belongs to the peptidase M16 family. (1019 aa) | ||||
STXBP3 | Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa) | ||||
APC | APC regulator of WNT signaling pathway. (2806 aa) | ||||
BCAR1 | BCAR1 scaffold protein, Cas family member. (916 aa) | ||||
PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) | ||||
GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (794 aa) | ||||
GCLC | Glutamate-cysteine ligase catalytic subunit. (587 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) | ||||
GRB10 | Growth factor receptor bound protein 10. (593 aa) | ||||
TRIB3 | Tribbles pseudokinase 3. (385 aa) | ||||
PDK2 | Protein-serine/threonine kinase. (407 aa) | ||||
SRC | Tyrosine-protein kinase. (542 aa) | ||||
MAX | MYC associated factor X. (160 aa) | ||||
RAB13 | Uncharacterized protein. (203 aa) | ||||
DENND4C | DENN domain containing 4C. (1927 aa) | ||||
PNPLA3 | Patatin like phospholipase domain containing 3. (462 aa) | ||||
PCK2 | Phosphoenolpyruvate carboxykinase 2, mitochondrial. (645 aa) | ||||
SP1 | Uncharacterized protein. (661 aa) | ||||
RHOQ | Ras homolog family member Q. (192 aa) | ||||
SCAP | SREBF chaperone. (1279 aa) | ||||
MEAK7 | MTOR associated protein, eak-7 homolog. (456 aa) | ||||
ZDHHC7 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (344 aa) | ||||
APRT | Adenine phosphoribosyltransferase. (157 aa) | ||||
ERRFI1 | ERBB receptor feedback inhibitor 1. (462 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (350 aa) | ||||
TRARG1 | Trafficking regulator of GLUT4 (SLC2A4) 1. (177 aa) | ||||
EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (517 aa) | ||||
CPEB1 | Cytoplasmic polyadenylation element binding protein 1. (620 aa) | ||||
RAB12 | Uncharacterized protein. (65 aa) | ||||
CRY2 | Cryptochrome circadian regulator 2. (614 aa) | ||||
PCSK9 | Proprotein convertase subtilisin/kexin type 9. (692 aa) | ||||
PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) | ||||
PDE3B | Phosphodiesterase. (1113 aa) | ||||
KCNQ1 | Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (592 aa) | ||||
UCP3 | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa) | ||||
ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) | ||||
ENSMLEP00000040511 | Uncharacterized protein. (645 aa) | ||||
SLC39A14 | Solute carrier family 39 member 14. (410 aa) | ||||
CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1233 aa) | ||||
OTC | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (328 aa) | ||||
ENSMLEP00000000301 | ANK_REP_REGION domain-containing protein. (297 aa) | ||||
SORT1 | Sortilin. (676 aa) | ||||
ENSMLEP00000000526 | Uncharacterized protein. (64 aa) | ||||
SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1077 aa) | ||||
SESN3 | Sestrin 3. (530 aa) | ||||
IGF2 | Insulin like growth factor 2. (236 aa) | ||||
ABCC8 | ATP binding cassette subfamily C member 8. (1582 aa) | ||||
LYN | Tyrosine-protein kinase. (470 aa) | ||||
PIK3R2 | Uncharacterized protein. (587 aa) | ||||
LOC105541640 | Uncharacterized protein. (526 aa) | ||||
INPPL1 | Inositol polyphosphate phosphatase like 1. (1235 aa) | ||||
STXBP4 | Syntaxin binding protein 4. (555 aa) | ||||
PARP1 | Poly [ADP-ribose] polymerase. (1017 aa) | ||||
SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa) | ||||
SLC2A8 | Solute carrier family 2 member 8; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (389 aa) | ||||
SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa) | ||||
PLA2G1B | Phospholipase A(2). (148 aa) | ||||
APPL1 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (694 aa) | ||||
GCNT1 | Glucosaminyl (N-acetyl) transferase 1. (428 aa) | ||||
SLC22A12 | Solute carrier family 22 member 12. (553 aa) | ||||
HADHA | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa) | ||||
EPM2AIP1 | EPM2A interacting protein 1. (607 aa) | ||||
SIRT1 | Sirtuin 1. (661 aa) | ||||
MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) | ||||
PTPN1 | Tyrosine-protein phosphatase non-receptor type. (435 aa) | ||||
CPEB2 | Uncharacterized protein. (480 aa) | ||||
ADM | Adrenomedullin. (200 aa) | ||||
RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) | ||||
WDTC1 | WD and tetratricopeptide repeats 1. (550 aa) | ||||
HADH | Hydroxyacyl-CoA dehydrogenase. (331 aa) | ||||
FBP1 | Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (298 aa) | ||||
ENSMLEP00000008862 | Uncharacterized protein. (116 aa) | ||||
IRS4 | Insulin receptor substrate 4. (1245 aa) |