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CALM2 CALM2 PDE4D PDE4D MCUB MCUB MICU1 MICU1 LOC105537369 LOC105537369 RYR2 RYR2 CATSPER3 CATSPER3 ENSMLEP00000010338 ENSMLEP00000010338 CALM1 CALM1 TRPC5 TRPC5 TRPC4 TRPC4 CACNB1 CACNB1 CATSPERD CATSPERD CACNG7 CACNG7 CACNG2 CACNG2 CACNB4 CACNB4 CACNA2D2 CACNA2D2 ORAI1 ORAI1 CACNB2 CACNB2 PKD2L1 PKD2L1 CACNG1 CACNG1 CACNA2D4 CACNA2D4 CACNG4 CACNG4 TMEM262 TMEM262 STAC3 STAC3 ASPH ASPH PTPA PTPA CACNA2D1 CACNA2D1 MCU MCU SMDT1 SMDT1 CACHD1 CACHD1 CACNA2D3 CACNA2D3 CACNA1S CACNA1S CATSPER4 CATSPER4 CACNG6 CACNG6 CALM3 CALM3 CACNA1B CACNA1B CACNA1A CACNA1A PDE4B PDE4B RYR1 RYR1 HSPA2 HSPA2 CACNA1I CACNA1I MICU3 MICU3 EFCAB9 EFCAB9 TRPV5 TRPV5 CACNA1C CACNA1C MICU2 MICU2 FKBP1B FKBP1B AKAP6 AKAP6 CATSPERG CATSPERG CACNA1G CACNA1G CACNA1F CACNA1F CATSPERE CATSPERE CACNA1E CACNA1E ENSMLEP00000020666 ENSMLEP00000020666 CACNA1D CACNA1D CATSPERB CATSPERB CATSPERZ CATSPERZ CATSPER1 CATSPER1 TRPV6 TRPV6 CACNA1H CACNA1H TMEM249 TMEM249 CACNB3 CACNB3 PKD1 PKD1 LOC105540811 LOC105540811 PKD1L1 PKD1L1 ATP2A1 ATP2A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CALM2Calmodulin 2. (149 aa)
PDE4DPhosphodiesterase. (748 aa)
MCUBMitochondrial calcium uniporter dominant negative beta subunit. (303 aa)
MICU1Uncharacterized protein. (482 aa)
LOC105537369Ion_trans domain-containing protein. (472 aa)
RYR2Ryanodine receptor 2. (4862 aa)
CATSPER3Cation channel sperm associated 3. (398 aa)
ENSMLEP00000010338Ion_trans domain-containing protein. (257 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (643 aa)
CATSPERDCation channel sperm associated auxiliary subunit delta. (712 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (262 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (490 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1081 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (238 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
PKD2L1Polycystin 2 like 1, transient receptor potential cation channel. (805 aa)
CACNG1Calcium voltage-gated channel auxiliary subunit gamma 1. (197 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1137 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (346 aa)
TMEM262Transmembrane protein 262. (116 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
ASPHAspartate beta-hydroxylase. (729 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (358 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (1018 aa)
MCUMitochondrial calcium uniporter. (318 aa)
SMDT1Single-pass membrane protein with aspartate rich tail 1. (107 aa)
CACHD1Cache domain containing 1. (1235 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1050 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1846 aa)
CATSPER4Cation channel sperm associated 4. (484 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (261 aa)
CALM3Calmodulin 3. (149 aa)
CACNA1BCalcium voltage-gated channel subunit alpha1 B. (2001 aa)
CACNA1ACalcium voltage-gated channel subunit alpha1 A. (1985 aa)
PDE4BPhosphodiesterase. (736 aa)
RYR1Ryanodine receptor 1. (4628 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (600 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2080 aa)
MICU3Mitochondrial calcium uptake family member 3. (422 aa)
EFCAB9EF-hand calcium binding domain 9. (153 aa)
TRPV5Transient receptor potential cation channel subfamily V member 5; Belongs to the transient receptor (TC 1.A.4) family. (729 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2169 aa)
MICU2Mitochondrial calcium uptake 2. (362 aa)
FKBP1BPeptidylprolyl isomerase. (95 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
CATSPERGCation channel sperm associated auxiliary subunit gamma. (1159 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2360 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1960 aa)
CATSPERECatsper channel auxiliary subunit epsilon. (906 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2315 aa)
ENSMLEP00000020666EF-hand domain-containing protein. (462 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2181 aa)
CATSPERBCation channel sperm associated auxiliary subunit beta. (1115 aa)
CATSPERZCatsper channel auxiliary subunit zeta. (200 aa)
CATSPER1Cation channel sperm associated 1. (768 aa)
TRPV6Transient receptor potential cation channel subfamily V member 6; Belongs to the transient receptor (TC 1.A.4) family. (770 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2170 aa)
TMEM249Transmembrane protein 249. (234 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4124 aa)
LOC105540811Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
PKD1L1Polycystin 1 like 1, transient receptor potential channel interacting. (2757 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1027 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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