(13 nodes) Maintenance of protein localization in endoplasmic reticulum network (Mandrillus leucophaeus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KDELR3	ER lumen protein-retaining receptor. (214 aa)
	INSIG2	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
	ENSMLEP00000017280	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (149 aa)
	ANKRD13C	Ankyrin repeat domain 13C. (541 aa)
	KDELR1	KDEL endoplasmic reticulum protein retention receptor 1. (220 aa)
	GPAA1	Glycosylphosphatidylinositol anchor attachment 1. (620 aa)
	KDELR2	ER lumen protein-retaining receptor. (181 aa)
	GRIK5	Glutamate ionotropic receptor kainate type subunit 5. (946 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
	ENSMLEP00000022361	Uncharacterized protein; Belongs to the heat shock protein 70 family. (580 aa)
	OS9	OS9 endoplasmic reticulum lectin. (716 aa)
	TAPT1	Transmembrane anterior posterior transformation 1. (461 aa)
	PDIA2	Protein disulfide isomerase family A member 2. (384 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMLEP00000022361	OS9	ENSMLEP00000022361	ENSMLEP00000002873	Uncharacterized protein; Belongs to the heat shock protein 70 family.	OS9 endoplasmic reticulum lectin.	0.597
ENSMLEP00000022361	PDIA2	ENSMLEP00000022361	ENSMLEP00000007142	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Protein disulfide isomerase family A member 2.	0.899
HSPA5	OS9	ENSMLEP00000022843	ENSMLEP00000002873	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	OS9 endoplasmic reticulum lectin.	0.597
HSPA5	PDIA2	ENSMLEP00000022843	ENSMLEP00000007142	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	Protein disulfide isomerase family A member 2.	0.899
OS9	ENSMLEP00000022361	ENSMLEP00000002873	ENSMLEP00000022361	OS9 endoplasmic reticulum lectin.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.597
OS9	HSPA5	ENSMLEP00000002873	ENSMLEP00000022843	OS9 endoplasmic reticulum lectin.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.597
OS9	PDIA2	ENSMLEP00000002873	ENSMLEP00000007142	OS9 endoplasmic reticulum lectin.	Protein disulfide isomerase family A member 2.	0.512
PDIA2	ENSMLEP00000022361	ENSMLEP00000007142	ENSMLEP00000022361	Protein disulfide isomerase family A member 2.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.899
PDIA2	HSPA5	ENSMLEP00000007142	ENSMLEP00000022843	Protein disulfide isomerase family A member 2.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.899
PDIA2	OS9	ENSMLEP00000007142	ENSMLEP00000002873	Protein disulfide isomerase family A member 2.	OS9 endoplasmic reticulum lectin.	0.512