STRINGSTRING
FZD4 FZD4 ERN2 ERN2 SYK SYK FZD10 FZD10 MAP3K11 MAP3K11 MAP3K7 MAP3K7 MAP4K2 MAP4K2 WNT5A WNT5A TNFRSF11A TNFRSF11A DVL2 DVL2 DUSP19 DUSP19 FGD2 FGD2 ERN1 ERN1 DVL3 DVL3 PAK1 PAK1 CCL19 CCL19 SASH1 SASH1 LOC105546431 LOC105546431 AXIN1 AXIN1 MAP2K7 MAP2K7 PTK2B PTK2B TAOK3 TAOK3 DAB2IP DAB2IP MAP3K13 MAP3K13 ARHGEF5 ARHGEF5 EPHA4 EPHA4 MAP3K12 MAP3K12 DKK1 DKK1 RPS3 RPS3 PTPN1 PTPN1 EDN1 EDN1 LOC105535581 LOC105535581 TRAF6 TRAF6 AGER AGER LOC105535945 LOC105535945 MAP3K5 MAP3K5 MAP3K4 MAP3K4 ENSMLEP00000038006 ENSMLEP00000038006 TRAF2 TRAF2 ROR2 ROR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (533 aa)
ERN2Endoplasmic reticulum to nucleus signaling 2. (821 aa)
SYKTyrosine-protein kinase. (618 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (847 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
MAP4K2Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (788 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
TNFRSF11ATNF receptor superfamily member 11a. (591 aa)
DVL2Dishevelled segment polarity protein 2. (736 aa)
DUSP19Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (217 aa)
FGD2FYVE, RhoGEF and PH domain containing 2. (655 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (959 aa)
DVL3Dishevelled segment polarity protein 3. (731 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
CCL19C-C motif chemokine. (103 aa)
SASH1SAM and SH3 domain containing 1. (1229 aa)
LOC105546431KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (256 aa)
AXIN1Axin 1. (859 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (442 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
TAOK3TAO kinase 3. (887 aa)
DAB2IPDAB2 interacting protein. (1153 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1601 aa)
EPHA4EPH receptor A4. (992 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (890 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (259 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
EDN1Endothelin 1. (211 aa)
LOC105535581Ribosomal_S3_C domain-containing protein. (250 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
LOC105535945Uncharacterized protein. (226 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1306 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1570 aa)
ENSMLEP00000038006Uncharacterized protein; Belongs to the protein kinase superfamily. (275 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (776 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.