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ENSMLEP00000005586 | ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (179 aa) | ||||
FURIN | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa) | ||||
ARIH2 | RBR-type E3 ubiquitin transferase. (471 aa) | ||||
ZYG11A | Zyg-11 family member A, cell cycle regulator. (671 aa) | ||||
RBX1 | RING-type domain-containing protein. (108 aa) | ||||
DDB1 | Damage specific DNA binding protein 1. (1147 aa) | ||||
BAG6 | BCL2 associated athanogene 6. (1162 aa) | ||||
PCSK9 | Proprotein convertase subtilisin/kexin type 9. (692 aa) | ||||
SIRT2 | Sirtuin 2. (528 aa) | ||||
ENSMLEP00000038668 | Prot_ATP_ID_OB domain-containing protein. (166 aa) | ||||
USP5 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (858 aa) | ||||
TNFRSF1B | TNF receptor superfamily member 1B. (462 aa) | ||||
FBXO22 | F-box protein 22. (404 aa) | ||||
TIPARP | TCDD inducible poly(ADP-ribose) polymerase. (657 aa) | ||||
SGTA | Small glutamine rich tetratricopeptide repeat containing alpha. (313 aa) | ||||
PACSIN3 | Protein kinase C and casein kinase substrate in neurons 3. (424 aa) | ||||
SH3D19 | SH3 domain containing 19. (1008 aa) | ||||
RNF180 | Uncharacterized protein. (416 aa) | ||||
DAB2 | DAB adaptor protein 2. (770 aa) | ||||
NFE2L2 | Nuclear factor, erythroid 2 like 2. (596 aa) | ||||
PRKN | Ubiquitin-like domain-containing protein. (368 aa) | ||||
STX5 | Syntaxin 5; Belongs to the syntaxin family. (361 aa) | ||||
ZNF268 | Zinc finger protein 268. (947 aa) | ||||
ZER1 | Zyg-11 related cell cycle regulator. (766 aa) | ||||
PIAS1 | Protein inhibitor of activated STAT 1. (653 aa) | ||||
ENSMLEP00000036399 | Uncharacterized protein. (95 aa) | ||||
FZR1 | Fizzy and cell division cycle 20 related 1. (522 aa) | ||||
NUPR1 | Nuclear protein 1, transcriptional regulator. (100 aa) | ||||
RNF14 | RBR-type E3 ubiquitin transferase. (474 aa) | ||||
ARIH1 | RBR-type E3 ubiquitin transferase. (407 aa) | ||||
TRIB3 | Tribbles pseudokinase 3. (385 aa) | ||||
RNF19B | RBR-type E3 ubiquitin transferase. (541 aa) | ||||
RCHY1 | Ring finger and CHY zinc finger domain containing 1. (261 aa) | ||||
CBLB | Cbl proto-oncogene B. (982 aa) | ||||
GCLC | Glutamate-cysteine ligase catalytic subunit. (587 aa) | ||||
DDRGK1 | DDRGK domain containing 1. (314 aa) | ||||
BAG2 | BCL2 associated athanogene 2. (175 aa) | ||||
GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (794 aa) | ||||
ENSMLEP00000033784 | Sox C-terminal domain-containing protein. (99 aa) | ||||
PLK3 | Serine/threonine-protein kinase PLK. (626 aa) | ||||
APC | APC regulator of WNT signaling pathway. (2806 aa) | ||||
IDE | Insulin degrading enzyme; Belongs to the peptidase M16 family. (1019 aa) | ||||
PRICKLE1 | Prickle planar cell polarity protein 1. (831 aa) | ||||
DACT1 | Dishevelled binding antagonist of beta catenin 1. (753 aa) | ||||
COP1 | COP1 E3 ubiquitin ligase. (731 aa) | ||||
C4BPB | Complement component 4 binding protein beta. (252 aa) | ||||
GGA3 | Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (723 aa) | ||||
OSBPL7 | Oxysterol-binding protein; Belongs to the OSBP family. (842 aa) | ||||
RAB7A | RAB7A, member RAS oncogene family. (207 aa) | ||||
PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (467 aa) | ||||
VIP | Vasoactive intestinal peptide. (170 aa) | ||||
LRP1 | LDL receptor related protein 1. (4546 aa) | ||||
ASB9 | Ankyrin repeat and SOCS box containing 9. (262 aa) | ||||
VGLL4 | Vestigial like family member 4. (296 aa) | ||||
SH3RF2 | SH3 domain containing ring finger 2. (729 aa) | ||||
PSMC6 | AAA domain-containing protein; Belongs to the AAA ATPase family. (403 aa) | ||||
SORL1 | Sortilin related receptor 1. (2218 aa) | ||||
RHBDD3 | Rhomboid domain containing 3. (386 aa) | ||||
XBP1 | X-box binding protein 1. (204 aa) | ||||
ENSMLEP00000030622 | Small ubiquitin-related modifier. (81 aa) | ||||
SGSM3 | Small G protein signaling modulator 3. (750 aa) | ||||
HSPBP1 | HSPA (Hsp70) binding protein 1. (342 aa) | ||||
RNFT1 | Ring finger protein, transmembrane 1. (401 aa) | ||||
RNF41 | Ring finger protein 41. (317 aa) | ||||
SMAD7 | MH2 domain-containing protein. (211 aa) | ||||
ANKIB1 | RBR-type E3 ubiquitin transferase. (826 aa) | ||||
ENSMLEP00000029005 | ATG7_N domain-containing protein. (78 aa) | ||||
CDC20B | Cell division cycle 20B. (477 aa) | ||||
TREM2 | Triggering receptor expressed on myeloid cells 2. (231 aa) | ||||
RGMA | Repulsive guidance molecule BMP co-receptor a. (458 aa) | ||||
GABARAP | GABA type A receptor-associated protein. (117 aa) | ||||
ENSMLEP00000028226 | RBR-type E3 ubiquitin transferase. (391 aa) | ||||
ADAM8 | ADAM metallopeptidase domain 8. (715 aa) | ||||
ASB5 | Ankyrin repeat and SOCS box containing 5. (322 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase. (432 aa) | ||||
LOC105529698 | Uncharacterized protein. (597 aa) | ||||
PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) | ||||
CDC20 | Cell division cycle 20. (499 aa) | ||||
EGLN2 | Egl-9 family hypoxia inducible factor 2. (405 aa) | ||||
CSNK2A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) | ||||
PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) | ||||
IL33 | Interleukin 33. (270 aa) | ||||
GGA1 | Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (639 aa) | ||||
LOC105538880 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa) | ||||
SNF8 | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa) | ||||
STUB1 | STIP1 homology and U-box containing protein 1. (250 aa) | ||||
HECTD1 | HECT domain E3 ubiquitin protein ligase 1. (2610 aa) | ||||
VPS11 | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa) | ||||
GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (603 aa) | ||||
FBXW9 | F-box and WD repeat domain containing 9. (458 aa) | ||||
MSN | Moesin. (581 aa) | ||||
AMER1 | APC membrane recruitment protein 1. (803 aa) | ||||
NKD2 | NKD inhibitor of WNT signaling pathway 2. (407 aa) | ||||
ATXN3 | Ataxin 3. (340 aa) | ||||
LOC105552274 | Uncharacterized protein. (906 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) | ||||
RNF144A | RBR-type E3 ubiquitin transferase. (249 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa) | ||||
APC2 | APC regulator of WNT signaling pathway 2. (1668 aa) | ||||
ENSMLEP00000024469 | Uncharacterized protein. (284 aa) | ||||
TRIB2 | Tribbles pseudokinase 2. (343 aa) | ||||
FMR1 | Fragile X mental retardation 1. (632 aa) | ||||
TNFSF12 | TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa) | ||||
SNX9 | Sorting nexin. (596 aa) | ||||
VCP | Valosin containing protein; Belongs to the AAA ATPase family. (806 aa) | ||||
RHBDD1 | Rhomboid domain containing 1. (316 aa) | ||||
FBXL5 | F-box and leucine rich repeat protein 5. (673 aa) | ||||
PLK1 | Serine/threonine-protein kinase PLK. (603 aa) | ||||
ENSMLEP00000022706 | Zf-rbx1 domain-containing protein. (93 aa) | ||||
ITCH | E3 ubiquitin-protein ligase. (862 aa) | ||||
FBXW7 | F-box and WD repeat domain containing 7. (707 aa) | ||||
OAZ3 | Ornithine decarboxylase antizyme 3. (235 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa) | ||||
OAZ2 | Ornithine decarboxylase antizyme 2. (189 aa) | ||||
LOC105536463 | AAA domain-containing protein; Belongs to the AAA ATPase family. (366 aa) | ||||
CLU | Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (449 aa) | ||||
DET1 | Uncharacterized protein. (562 aa) | ||||
TAF1 | Transcription initiation factor TFIID subunit. (1881 aa) | ||||
ENSMLEP00000021441 | FERM domain-containing protein. (478 aa) | ||||
SUMO1 | Ubiquitin-like domain-containing protein. (62 aa) | ||||
HERPUD1 | Homocysteine inducible ER protein with ubiquitin like domain 1. (391 aa) | ||||
ENSMLEP00000019789 | ANK_REP_REGION domain-containing protein. (165 aa) | ||||
PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) | ||||
RILP | Rab interacting lysosomal protein. (253 aa) | ||||
RNF19A | RBR-type E3 ubiquitin transferase. (838 aa) | ||||
TMTC3 | Transmembrane O-mannosyltransferase targeting cadherins 3. (914 aa) | ||||
DTL | Denticleless E3 ubiquitin protein ligase homolog. (730 aa) | ||||
RACK1 | Receptor for activated C kinase 1. (318 aa) | ||||
USP13 | Ubiquitin specific peptidase 13; Belongs to the peptidase C19 family. (458 aa) | ||||
PSMC3 | AAA domain-containing protein; Belongs to the AAA ATPase family. (446 aa) | ||||
NEDD4 | NEDD4 E3 ubiquitin protein ligase. (1272 aa) | ||||
ECSCR | Uncharacterized protein. (205 aa) | ||||
ENSMLEP00000016698 | AAA domain-containing protein; Belongs to the AAA ATPase family. (390 aa) | ||||
NOP53 | Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (466 aa) | ||||
NKD1 | NKD inhibitor of WNT signaling pathway 1. (501 aa) | ||||
ENSMLEP00000016378 | AAA domain-containing protein. (201 aa) | ||||
PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) | ||||
AXIN1 | Axin 1. (859 aa) | ||||
ENSMLEP00000015948 | Uncharacterized protein. (90 aa) | ||||
ENSMLEP00000015845 | Rad60-SLD domain-containing protein. (78 aa) | ||||
BBS7 | Bardet-Biedl syndrome 7. (503 aa) | ||||
LRRK2 | Leucine rich repeat kinase 2. (2182 aa) | ||||
ENSMLEP00000015404 | Fork-head domain-containing protein. (531 aa) | ||||
ENSMLEP00000015186 | Uncharacterized protein. (338 aa) | ||||
ENSMLEP00000015075 | RBR-type E3 ubiquitin transferase. (290 aa) | ||||
SEC22B | SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa) | ||||
BARD1 | BRCA1 associated RING domain 1. (759 aa) | ||||
OAZ1 | Ornithine decarboxylase antizyme 1. (195 aa) | ||||
SIRT6 | Sirtuin 6. (355 aa) | ||||
ENSMLEP00000013987 | Uncharacterized protein. (60 aa) | ||||
C4BPA | Complement component 4 binding protein alpha. (597 aa) | ||||
HAMP | Hepcidin antimicrobial peptide. (84 aa) | ||||
RNFT2 | Ring finger protein, transmembrane 2. (435 aa) | ||||
CSNK1D | Casein kinase 1 delta. (434 aa) | ||||
DAB2IP | DAB2 interacting protein. (1153 aa) | ||||
LOC105537007 | Ubiquitin-like domain-containing protein. (103 aa) | ||||
LDLR | Low density lipoprotein receptor. (860 aa) | ||||
ZYG11B | Zyg-11 family member B, cell cycle regulator. (761 aa) | ||||
NDFIP1 | Nedd4 family interacting protein 1. (200 aa) | ||||
ADAM9 | ADAM metallopeptidase domain 9. (819 aa) | ||||
CBFA2T3 | CBFA2/RUNX1 partner transcriptional co-repressor 3. (589 aa) | ||||
CUL4B | Cullin 4B; Belongs to the cullin family. (931 aa) | ||||
LRP2 | LDL receptor related protein 2. (4655 aa) | ||||
CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) | ||||
FBXW8 | F-box and WD repeat domain containing 8. (492 aa) | ||||
CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa) | ||||
RNF185 | Ring finger protein 185. (195 aa) | ||||
AXIN2 | Axin 2. (843 aa) | ||||
ENSMLEP00000008857 | Uncharacterized protein. (263 aa) | ||||
VPS35 | Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (664 aa) | ||||
ENSMLEP00000008466 | Josephin domain-containing protein. (133 aa) | ||||
LOC105534357 | RBR-type E3 ubiquitin transferase. (77 aa) | ||||
FAF1 | Fas associated factor 1. (490 aa) | ||||
MYLIP | Myosin regulatory light chain interacting protein. (445 aa) | ||||
LOC105546533 | ANK_REP_REGION domain-containing protein. (271 aa) | ||||
DVL1 | Dishevelled segment polarity protein 1. (591 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (395 aa) | ||||
UBQLN2 | Ubiquilin 2. (624 aa) | ||||
SOCS5 | Suppressor of cytokine signaling 5. (536 aa) | ||||
EZR | Ezrin. (588 aa) | ||||
ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (704 aa) | ||||
NDUFA13 | NADH:ubiquinone oxidoreductase subunit A13. (163 aa) | ||||
ENSMLEP00000006413 | AAA domain-containing protein; Belongs to the AAA ATPase family. (423 aa) | ||||
TRIM32 | Tripartite motif containing 32. (653 aa) | ||||
ENSMLEP00000006383 | Uncharacterized protein. (234 aa) | ||||
SNX33 | Sorting nexin. (574 aa) | ||||
RAD23A | RAD23 homolog A, nucleotide excision repair protein. (363 aa) | ||||
RNF144B | RBR-type E3 ubiquitin transferase. (303 aa) | ||||
TNFAIP3 | TNF alpha induced protein 3. (790 aa) | ||||
CLUL1 | Clusterin; Belongs to the clusterin family. (506 aa) | ||||
PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) | ||||
TAF1L | Transcription initiation factor TFIID subunit. (1884 aa) | ||||
DNAJB2 | DnaJ heat shock protein family (Hsp40) member B2. (324 aa) | ||||
ENSMLEP00000003274 | Uncharacterized protein. (105 aa) | ||||
ENSMLEP00000002739 | RBR-type E3 ubiquitin transferase. (273 aa) | ||||
MKRN2 | Makorin ring finger protein 2. (405 aa) | ||||
SH3RF3 | SH3 domain containing ring finger 3. (731 aa) | ||||
KLHL40 | Kelch like family member 40. (621 aa) | ||||
AURKA | Aurora kinase A; Belongs to the protein kinase superfamily. (384 aa) | ||||
TRIB1 | Tribbles pseudokinase 1. (372 aa) | ||||
SOCS4 | Suppressor of cytokine signaling 4. (440 aa) | ||||
CREBRF | CREB3 regulatory factor. (639 aa) | ||||
PLK2 | Serine/threonine-protein kinase PLK. (685 aa) | ||||
NUB1 | Negative regulator of ubiquitin like proteins 1. (610 aa) |