STRINGSTRING
PLK2 PLK2 CYBB CYBB FKBPL FKBPL APLNR APLNR APOH APOH GPR4 GPR4 ABCC8 ABCC8 FGF1 FGF1 THBS2 THBS2 LOC105541640 LOC105541640 APELA APELA SPRED1 SPRED1 HK2 HK2 ENSMLEP00000003227 ENSMLEP00000003227 HRG HRG RHOB RHOB LOC105530554 LOC105530554 SMOC2 SMOC2 BTG1 BTG1 RECK RECK ABL1 ABL1 GRN GRN PDCD10 PDCD10 SIRT1 SIRT1 ECM1 ECM1 IL17F IL17F COL4A3 COL4A3 NAXE NAXE FUT1 FUT1 RRAS RRAS ISL1 ISL1 EPN1 EPN1 TJP1 TJP1 PML PML ADM ADM ENSMLEP00000007151 ENSMLEP00000007151 CHI3L1 CHI3L1 CDH5 CDH5 ENG ENG MAPK7 MAPK7 LOC105553391 LOC105553391 PTGIS PTGIS RUNX1 RUNX1 CYSLTR1 CYSLTR1 GATA4 GATA4 KRIT1 KRIT1 HGS HGS LOC105537373 LOC105537373 WARS2 WARS2 CTNNB1 CTNNB1 ADGRB3 ADGRB3 CCL24 CCL24 PGF PGF BMPER BMPER ROCK2 ROCK2 OR10J5 OR10J5 RHOJ RHOJ SPARC SPARC SPINK5 SPINK5 EMC10 EMC10 GLUL GLUL CD40 CD40 FGF18 FGF18 VASH2 VASH2 GTF2I GTF2I F3 F3 PDPK1 PDPK1 ANGPT2 ANGPT2 KLF4 KLF4 STAT3 STAT3 DAB2IP DAB2IP CCBE1 CCBE1 ANGPTL4 ANGPTL4 RNH1 RNH1 ITGAX ITGAX EGLN1 EGLN1 GHSR GHSR C3 C3 PTK2B PTK2B JUP JUP SIRT6 SIRT6 CCR3 CCR3 NOS3 NOS3 GDF2 GDF2 HPSE HPSE MTDH MTDH BRCA1 BRCA1 ZNF304 ZNF304 E2F2 E2F2 NODAL NODAL ITGB3 ITGB3 TERT TERT IL10 IL10 CXCL8 CXCL8 LOC105554401 LOC105554401 CXCR3 CXCR3 SFRP1 SFRP1 TNN TNN AGGF1 AGGF1 MINAR1 MINAR1 CD34 CD34 EMP2 EMP2 SYNJ2BP SYNJ2BP CYP1B1 CYP1B1 HIF1A HIF1A TIE1 TIE1 GAB1 GAB1 STIM1 STIM1 ERBB2 ERBB2 LOC105544513 LOC105544513 MECP2 MECP2 EPHA2 EPHA2 HOXA5 HOXA5 ECSCR ECSCR HMOX1 HMOX1 SASH1 SASH1 DLL1 DLL1 FGF2 FGF2 CD160 CD160 SEMA4A SEMA4A GADD45A GADD45A DDAH1 DDAH1 HSPG2 HSPG2 C5 C5 SMAD1 SMAD1 FLT1 FLT1 C5AR1 C5AR1 ISM1 ISM1 ALOX5 ALOX5 ZC3H12A ZC3H12A STAB1 STAB1 ENSMLEP00000020896 ENSMLEP00000020896 ENPP2 ENPP2 EPHA1 EPHA1 NF1 NF1 CREB3L1 CREB3L1 HMGA2 HMGA2 VEGFC VEGFC CX3CR1 CX3CR1 HIPK2 HIPK2 PDE3B PDE3B JCAD JCAD VEGFD VEGFD NRP1 NRP1 EMILIN1 EMILIN1 NIBAN2 NIBAN2 TNMD TNMD SEMA6A SEMA6A CXCL13 CXCL13 COL4A2 COL4A2 ANXA3 ANXA3 ROCK1 ROCK1 NFE2L2 NFE2L2 SP1 SP1 RTN4 RTN4 GPNMB GPNMB CELA1 CELA1 AKT3 AKT3 CHRNA7 CHRNA7 ENSMLEP00000036527 ENSMLEP00000036527 LOC105543400 LOC105543400 CCM2 CCM2 TGFBR2 TGFBR2 TGFB2 TGFB2 TBC1D31 TBC1D31 NR2E1 NR2E1 PKM PKM EPN2 EPN2 CNMD CNMD PAK4 PAK4 ADAMTS1 ADAMTS1 EMILIN2 EMILIN2 RAPGEF3 RAPGEF3 AQP1 AQP1 PPP1R16B PPP1R16B HTATIP2 HTATIP2 NPR1 NPR1 LEP LEP GATA2 GATA2 THBS4 THBS4 SEMA3E SEMA3E PRKD2 PRKD2 EFNA1 EFNA1 HIPK1 HIPK1 SEMA5A SEMA5A ACVRL1 ACVRL1 TBXA2R TBXA2R CLDN5 CLDN5 ANGPTL3 ANGPTL3 FOXO4 FOXO4 PROK1 PROK1 VASH1 VASH1 HYAL1 HYAL1 DCN DCN CXCL10 CXCL10 SPRY2 SPRY2 ERAP1 ERAP1 ADGRA2 ADGRA2 LOC105548563 LOC105548563 VEGFB VEGFB PTPRM PTPRM SFRP2 SFRP2 SERPINE1 SERPINE1 ADGRB1 ADGRB1 XBP1 XBP1 LRG1 LRG1 RLN2 RLN2 SERPINF1 SERPINF1 HHEX HHEX HSPB6 HSPB6 AMOT AMOT STAT1 STAT1 AGO2 AGO2 KDR KDR GHRL GHRL TEK TEK NTRK1 NTRK1 ETS1 ETS1 VEGFA VEGFA PLCG1 PLCG1 TLR3 TLR3 PRKD1 PRKD1 AGO1 AGO1 JAK1 JAK1 ADAMTS9 ADAMTS9 PIK3CB PIK3CB WNT5A WNT5A SP100 SP100 RAMP2 RAMP2 PLXND1 PLXND1 FASLG FASLG RGCC RGCC PIK3CD PIK3CD ITGB8 ITGB8 ADGRB2 ADGRB2 ITGB2 ITGB2 SULF1 SULF1 ADAM12 ADAM12 NPPB NPPB ITGA5 ITGA5 FOXJ2 FOXJ2 MDK MDK SPHK1 SPHK1 IL1B IL1B FOXC2 FOXC2 PRKCB PRKCB TSPAN12 TSPAN12 TNFSF12 TNFSF12 PF4 PF4 JMJD8 JMJD8 ATP2B4 ATP2B4 SARS1 SARS1 HGF HGF ATF2 ATF2 ADM2 ADM2 THBS1 THBS1 ANGPT4 ANGPT4 MYDGF MYDGF CTSH CTSH PIK3R6 PIK3R6 WARS1 WARS1 PRKCA PRKCA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLK2Serine/threonine-protein kinase PLK. (685 aa)
CYBBCytochrome b-245 beta chain. (486 aa)
FKBPLFKBP prolyl isomerase like. (349 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
APOHApolipoprotein H. (345 aa)
GPR4G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
THBS2Thrombospondin 2. (1008 aa)
LOC105541640Uncharacterized protein. (526 aa)
APELAUncharacterized protein. (54 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
HK2Hexokinase 2. (901 aa)
ENSMLEP00000003227Uncharacterized protein. (103 aa)
HRGHistidine rich glycoprotein. (516 aa)
RHOBRas homolog family member B. (196 aa)
LOC105530554Uncharacterized protein. (143 aa)
SMOC2SPARC related modular calcium binding 2. (446 aa)
BTG1BTG anti-proliferation factor 1. (96 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (970 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
GRNGranulin precursor. (593 aa)
PDCD10Uncharacterized protein. (212 aa)
SIRT1Sirtuin 1. (661 aa)
ECM1Extracellular matrix protein 1. (567 aa)
IL17FInterleukin 17F. (163 aa)
COL4A3Collagen type IV alpha 3 chain. (1635 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (366 aa)
RRASRAS related. (218 aa)
ISL1ISL LIM homeobox 1. (349 aa)
EPN1Epsin 1. (662 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1738 aa)
PMLPromyelocytic leukemia. (858 aa)
ADMAdrenomedullin. (200 aa)
ENSMLEP00000007151Pyruvate kinase; Belongs to the pyruvate kinase family. (293 aa)
CHI3L1Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (383 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (705 aa)
ENGEndoglin. (598 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
LOC105553391Uncharacterized protein. (106 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (423 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
CYSLTR1Cysteinyl leukotriene receptor 1. (337 aa)
GATA4GATA binding protein 4. (236 aa)
KRIT1Uncharacterized protein. (736 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (815 aa)
LOC105537373Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (728 aa)
WARS2Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (360 aa)
CTNNB1Catenin beta 1. (781 aa)
ADGRB3Adhesion G protein-coupled receptor B3. (803 aa)
CCL24C-C motif chemokine ligand 24. (119 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
BMPERBMP binding endothelial regulator. (686 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1375 aa)
OR10J5Olfactory receptor family 10 subfamily J member 5. (300 aa)
RHOJRas homolog family member J. (214 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
SPINK5Serine peptidase inhibitor, Kazal type 5. (1086 aa)
EMC10ER membrane protein complex subunit 10. (260 aa)
GLULGlutamine synthetase. (373 aa)
CD40CD40 molecule. (278 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
VASH2Vasohibin 2. (314 aa)
GTF2IGeneral transcription factor IIi. (998 aa)
F3Coagulation factor III, tissue factor. (296 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (529 aa)
ANGPT2Angiopoietin 2. (496 aa)
KLF4Uncharacterized protein. (145 aa)
STAT3Signal transducer and activator of transcription. (693 aa)
DAB2IPDAB2 interacting protein. (1153 aa)
CCBE1Collagen and calcium binding EGF domains 1. (406 aa)
ANGPTL4Angiopoietin like 4. (406 aa)
RNH1Ribonuclease/angiogenin inhibitor 1. (456 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1163 aa)
EGLN1Fe2OG dioxygenase domain-containing protein. (128 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
C3Complement C3. (1601 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
JUPJunction plakoglobin. (745 aa)
SIRT6Sirtuin 6. (355 aa)
CCR3C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1155 aa)
GDF2Growth differentiation factor 2. (429 aa)
HPSEHeparanase. (545 aa)
MTDHMetadherin. (582 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1843 aa)
ZNF304Zinc finger protein 304. (707 aa)
E2F2E2F transcription factor 2. (437 aa)
NODALNodal growth differentiation factor. (303 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (360 aa)
IL10Interleukin 10. (178 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
LOC105554401Pyruvate kinase; Belongs to the pyruvate kinase family. (504 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
SFRP1Secreted frizzled related protein 1. (206 aa)
TNNTenascin N. (1299 aa)
AGGF1Uncharacterized protein. (710 aa)
MINAR1Membrane integral NOTCH2 associated receptor 1. (916 aa)
CD34CD34 molecule. (385 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (758 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
STIM1Stromal interaction molecule 1. (790 aa)
ERBB2Receptor protein-tyrosine kinase. (1260 aa)
LOC105544513Uncharacterized protein. (144 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
EPHA2EPH receptor A2. (976 aa)
HOXA5Homeobox A5. (188 aa)
ECSCRUncharacterized protein. (205 aa)
HMOX1Heme oxygenase 1. (311 aa)
SASH1SAM and SH3 domain containing 1. (1229 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (606 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
CD160CD160 molecule. (232 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (760 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
DDAH1Dimethylarginine dimethylaminohydrolase 1. (185 aa)
HSPG2Heparan sulfate proteoglycan 2. (4358 aa)
C5Complement C5. (1676 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1316 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
ISM1Isthmin 1. (418 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (601 aa)
STAB1Stabilin 1. (2572 aa)
ENSMLEP00000020896Uncharacterized protein. (486 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa)
EPHA1EPH receptor A1. (948 aa)
NF1Neurofibromin 1. (2839 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (466 aa)
HMGA2High mobility group AT-hook 2. (109 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (402 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (384 aa)
HIPK2Homeodomain interacting protein kinase 2. (1196 aa)
PDE3BPhosphodiesterase. (1113 aa)
JCADJunctional cadherin 5 associated. (1356 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
EMILIN1Elastin microfibril interfacer 1. (1016 aa)
NIBAN2Niban apoptosis regulator 2. (746 aa)
TNMDTenomodulin. (257 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
CXCL13C-X-C motif chemokine. (109 aa)
COL4A2Collagen type IV alpha 2 chain. (1673 aa)
ANXA3Annexin. (291 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (596 aa)
SP1Uncharacterized protein. (661 aa)
RTN4Reticulon. (1007 aa)
GPNMBGlycoprotein nmb. (573 aa)
CELA1Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (257 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
CHRNA7Uncharacterized protein. (473 aa)
ENSMLEP00000036527Uncharacterized protein. (89 aa)
LOC105543400Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (335 aa)
CCM2CCM2 scaffold protein. (466 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (560 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TBC1D31Uncharacterized protein. (1067 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (556 aa)
EPN2Epsin 2. (643 aa)
CNMDChondromodulin. (287 aa)
PAK4Non-specific serine/threonine protein kinase. (349 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (967 aa)
EMILIN2Elastin microfibril interfacer 2. (881 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (925 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (568 aa)
HTATIP2HIV-1 Tat interactive protein 2. (239 aa)
NPR1Guanylate cyclase. (900 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
GATA2GATA binding protein 2. (480 aa)
THBS4Thrombospondin 4. (961 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (744 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (888 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
SEMA5ASemaphorin 5A. (1027 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
TBXA2RThromboxane A2 receptor. (329 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (277 aa)
ANGPTL3Angiopoietin like 3. (459 aa)
FOXO4Forkhead box O4. (505 aa)
PROK1Prokineticin 1. (105 aa)
VASH1Vasohibin 1. (365 aa)
HYAL1Hyaluronidase. (435 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
CXCL10C-X-C motif chemokine. (98 aa)
SPRY2Sprouty RTK signaling antagonist 2. (338 aa)
ERAP1Aminopeptidase. (939 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1303 aa)
LOC105548563Uncharacterized protein. (245 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (168 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1403 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1495 aa)
XBP1X-box binding protein 1. (204 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (347 aa)
RLN2Relaxin 2. (185 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
HHEXHomeobox domain-containing protein. (98 aa)
HSPB6Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (160 aa)
AMOTAngiomotin. (1085 aa)
STAT1Signal transducer and activator of transcription. (758 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (888 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (210 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1276 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (832 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1073 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SP100SP100 nuclear antigen. (866 aa)
RAMP2Receptor activity modifying protein 2. (216 aa)
PLXND1Uncharacterized protein. (52 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (280 aa)
RGCCRegulator of cell cycle. (234 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (769 aa)
ADGRB2Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family. (1587 aa)
ITGB2Integrin beta. (769 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
ADAM12ADAM metallopeptidase domain 12. (879 aa)
NPPBNatriuretic peptide B. (132 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1053 aa)
FOXJ2Forkhead box J2. (555 aa)
MDKUncharacterized protein. (161 aa)
SPHK1Sphingosine kinase 1. (470 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
FOXC2Forkhead box C2. (254 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
TSPAN12Tetraspanin. (305 aa)
TNFSF12TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa)
PF4C-X-C motif chemokine. (101 aa)
JMJD8Jumonji domain containing 8. (236 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1241 aa)
SARS1Seryl-tRNA synthetase. (448 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
ADM2Adrenomedullin 2. (145 aa)
THBS1Thrombospondin 1. (1170 aa)
ANGPT4Angiopoietin 4. (503 aa)
MYDGFMyeloid derived growth factor. (156 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (332 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (754 aa)
WARS1Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (475 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (614 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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