STRINGSTRING
RAB3D RAB3D CLASP1 CLASP1 HYAL3 HYAL3 CADPS2 CADPS2 RAB2B RAB2B SMPD3 SMPD3 ENSMLEP00000036399 ENSMLEP00000036399 ENSMLEP00000035626 ENSMLEP00000035626 ENSMLEP00000035344 ENSMLEP00000035344 LOC105539755 LOC105539755 LOC105537009 LOC105537009 STAM STAM CFTR CFTR FGG FGG STX1A STX1A GATA2 GATA2 PLA2G6 PLA2G6 RAB7A RAB7A DOC2B DOC2B SYT10 SYT10 NLGN1 NLGN1 CNR2 CNR2 VSNL1 VSNL1 S100A10 S100A10 LAMP1 LAMP1 RAB9A RAB9A FGB FGB IL13 IL13 CACNA1H CACNA1H ENSMLEP00000005644 ENSMLEP00000005644 KIAA0100 KIAA0100 LOC105539461 LOC105539461 PDCD6IP PDCD6IP HGS HGS LOC105535298 LOC105535298 ENSMLEP00000008924 ENSMLEP00000008924 CD177 CD177 SYT9 SYT9 CADPS CADPS SYT1 SYT1 SDCBP SDCBP SDC1 SDC1 GATA1 GATA1 EXPH5 EXPH5 ENSMLEP00000014987 ENSMLEP00000014987 SNX4 SNX4 ITGAM ITGAM RAB27B RAB27B SYT4 SYT4 IL4R IL4R FGR FGR CACNB4 CACNB4 ENSMLEP00000017246 ENSMLEP00000017246 SYT7 SYT7 SDC4 SDC4 FGA FGA CACNB2 CACNB2 CD160 CD160 SLC4A8 SLC4A8 CHMP2A CHMP2A CDK5 CDK5 ENSMLEP00000019778 ENSMLEP00000019778 UNC13D UNC13D CACNA1G CACNA1G SCAMP5 SCAMP5 VAMP8 VAMP8 VPS4A VPS4A TSG101 TSG101 ITGB2 ITGB2 ATP13A2 ATP13A2 ENSMLEP00000026510 ENSMLEP00000026510 SNF8 SNF8 RAB15 RAB15 ENSMLEP00000028396 ENSMLEP00000028396 ADORA2B ADORA2B CACNA1I CACNA1I STX4 STX4 SYTL4 SYTL4 PLA2G3 PLA2G3 STXBP5 STXBP5 ENSMLEP00000031001 ENSMLEP00000031001 RAB27A RAB27A SYK SYK SPHK2 SPHK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAB3DRAB3D, member RAS oncogene family. (219 aa)
CLASP1Cytoplasmic linker associated protein 1. (1533 aa)
HYAL3Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Belongs to the glycosyl hydrolase 56 family. (417 aa)
CADPS2Calcium dependent secretion activator 2. (1242 aa)
RAB2BRAB2B, member RAS oncogene family. (216 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
ENSMLEP00000036399Uncharacterized protein. (95 aa)
ENSMLEP00000035626Ig-like domain-containing protein; Belongs to the MHC class I family. (313 aa)
ENSMLEP00000035344Uncharacterized protein. (198 aa)
LOC105539755PDZ domain-containing protein. (290 aa)
LOC105537009PDZ domain-containing protein. (157 aa)
STAMSignal transducing adaptor molecule. (540 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1484 aa)
FGGFibrinogen gamma chain. (453 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (288 aa)
GATA2GATA binding protein 2. (480 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
DOC2BDouble C2 domain beta. (357 aa)
SYT10Synaptotagmin 10. (523 aa)
NLGN1Neuroligin 1. (823 aa)
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
VSNL1Visinin like 1. (191 aa)
S100A10S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
LAMP1Lysosomal associated membrane protein 1. (410 aa)
RAB9ARAB9A, member RAS oncogene family. (201 aa)
FGBFibrinogen beta chain. (491 aa)
IL13Interleukin 13. (146 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2170 aa)
ENSMLEP00000005644Ig-like domain-containing protein; Belongs to the MHC class I family. (216 aa)
KIAA0100KIAA0100. (2176 aa)
LOC105539461Cytoplasmic linker associated protein 2. (702 aa)
PDCD6IPProgrammed cell death 6 interacting protein. (873 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (815 aa)
LOC105535298Ig-like domain-containing protein; Belongs to the MHC class I family. (345 aa)
ENSMLEP00000008924PDZ domain-containing protein. (294 aa)
CD177CD177 molecule. (430 aa)
SYT9Synaptotagmin 9. (491 aa)
CADPSCalcium dependent secretion activator. (1242 aa)
SYT1Synaptotagmin 1. (422 aa)
SDCBPSyndecan binding protein. (318 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (332 aa)
GATA1GATA binding protein 1. (413 aa)
EXPH5Exophilin 5. (1950 aa)
ENSMLEP00000014987IGc1 domain-containing protein; Belongs to the MHC class I family. (327 aa)
SNX4Sorting nexin 4. (369 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
SYT4Synaptotagmin 4. (425 aa)
IL4RInterleukin 4 receptor. (819 aa)
FGRTyrosine-protein kinase. (529 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (490 aa)
ENSMLEP00000017246Uncharacterized protein. (149 aa)
SYT7Synaptotagmin 7. (684 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
FGAFibrinogen alpha chain. (861 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
CD160CD160 molecule. (232 aa)
SLC4A8Anion exchange protein. (1093 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (302 aa)
ENSMLEP00000019778IGc1 domain-containing protein; Belongs to the MHC class I family. (327 aa)
UNC13DUnc-13 homolog D. (1090 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2360 aa)
SCAMP5Secretory carrier-associated membrane protein. (243 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (474 aa)
TSG101Tumor susceptibility 101. (390 aa)
ITGB2Integrin beta. (769 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1182 aa)
ENSMLEP00000026510Ig-like domain-containing protein; Belongs to the MHC class I family. (301 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
RAB15RAB15, member RAS oncogene family. (257 aa)
ENSMLEP00000028396IGc1 domain-containing protein. (205 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2080 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
SYTL4Synaptotagmin like 4. (670 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
STXBP5Syntaxin binding protein 5. (1152 aa)
ENSMLEP00000031001Ig-like domain-containing protein; Belongs to the MHC class I family. (333 aa)
RAB27ARAB27A, member RAS oncogene family. (179 aa)
SYKTyrosine-protein kinase. (618 aa)
SPHK2Sphingosine kinase 2. (663 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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