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| | ENSMLEP00000000301 | ANK_REP_REGION domain-containing protein. (297 aa) |
| | CLK2 | CDC like kinase 2. (507 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (637 aa) |
| | IGF2 | Insulin like growth factor 2. (236 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (802 aa) |
| | ZNF692 | Zinc finger protein 692. (524 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | SERPINA12 | Serpin family A member 12; Belongs to the serpin family. (414 aa) |
| | LOC105541640 | Uncharacterized protein. (526 aa) |
| | REST | RE1 silencing transcription factor. (1095 aa) |
| | ENSMLEP00000002280 | Biotin carboxylation domain-containing protein. (205 aa) |
| | LOC105537501 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (517 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (657 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase. (1017 aa) |
| | PID1 | Phosphotyrosine interaction domain containing 1. (250 aa) |
| | CD244 | CD244 molecule. (370 aa) |
| | SLC7A7 | Solute carrier family 7 member 7. (511 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | LOC105530911 | Uncharacterized protein. (251 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (542 aa) |
| | LEPR | Leptin receptor. (1163 aa) |
| | DGKQ | Diacylglycerol kinase. (778 aa) |
| | MAS1 | MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa) |
| | ABCG4 | ATP binding cassette subfamily G member 4. (646 aa) |
| | ADCYAP1R1 | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (523 aa) |
| | EPM2AIP1 | EPM2A interacting protein 1. (607 aa) |
| | SIRT1 | Sirtuin 1. (661 aa) |
| | TSPO | Translocator protein. (169 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | MALRD1 | MAM and LDL receptor class A domain containing 1. (2157 aa) |
| | P2RY6 | Pyrimidinergic receptor P2Y6. (328 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | IGF1 | Insulin like growth factor 1. (159 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (486 aa) |
| | FMO5 | Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa) |
| | P2RY1 | Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (463 aa) |
| | ADM | Adrenomedullin. (200 aa) |
| | FOXK1 | Forkhead box K1. (652 aa) |
| | ENSMLEP00000007059 | Uncharacterized protein. (169 aa) |
| | TTC39A | Tetratricopeptide repeat domain 39A. (612 aa) |
| | FMO1 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) |
| | CLCN2 | Chloride voltage-gated channel 2. (898 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (550 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (802 aa) |
| | PPTC7 | Protein phosphatase; Belongs to the PP2C family. (272 aa) |
| | LOC105551919 | Uncharacterized protein. (432 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A. (471 aa) |
| | LOC105534357 | RBR-type E3 ubiquitin transferase. (77 aa) |
| | LOC105534833 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (252 aa) |
| | RORA | RAR related orphan receptor A. (555 aa) |
| | FBP1 | Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (298 aa) |
| | ENSMLEP00000008495 | START domain-containing protein. (261 aa) |
| | ACTN3 | Actinin alpha 3 (gene/pseudogene). (916 aa) |
| | ENSMLEP00000008862 | Uncharacterized protein. (116 aa) |
| | ENSMLEP00000008990 | Uncharacterized protein. (858 aa) |
| | BEND3 | BEN domain containing 3. (828 aa) |
| | DHCR7 | 7-dehydrocholesterol reductase. (475 aa) |
| | STARD4 | StAR related lipid transfer domain containing 4. (205 aa) |
| | C1QTNF12 | C1q and TNF related 12. (243 aa) |
| | RD3 | Retinal degeneration 3, GUCY2D regulator. (195 aa) |
| | CLYBL | Citrate lyase beta like. (360 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa) |
| | SLC22A13 | Solute carrier family 22 member 13. (551 aa) |
| | FABP1 | Fatty acid binding protein 1. (127 aa) |
| | EPHX2 | Epoxide hydrolase 2. (521 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | IRS1 | Insulin receptor substrate 1. (1242 aa) |
| | ENSMLEP00000010887 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (415 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (757 aa) |
| | CBFA2T3 | CBFA2/RUNX1 partner transcriptional co-repressor 3. (589 aa) |
| | AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa) |
| | APOA5 | Apolipoprotein A5. (366 aa) |
| | ERLIN1 | ER lipid raft associated 1. (348 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa) |
| | LDLR | Low density lipoprotein receptor. (860 aa) |
| | LOC105532487 | Aldo-keto reductase family 1 member C1. (323 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) |
| | NOS1 | Nitric oxide synthase; Produces nitric oxide (NO). (1404 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (670 aa) |
| | FOXA2 | Forkhead box A2. (463 aa) |
| | STAT3 | Signal transducer and activator of transcription. (693 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | ENSMLEP00000013040 | Uncharacterized protein. (131 aa) |
| | POTEA | POTE ankyrin domain family member A. (526 aa) |
| | GHSR | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa) |
| | GUCA1A | Uncharacterized protein. (202 aa) |
| | SIRT6 | Sirtuin 6. (355 aa) |
| | NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1155 aa) |
| | CD320 | CD320 molecule. (174 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | FAM3A | Family with sequence similarity 3 member A. (244 aa) |
| | FMO2 | Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (553 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1843 aa) |
| | KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (778 aa) |
| | ATP5IF1 | ATP synthase inhibitory factor subunit 1. (106 aa) |
| | ENSMLEP00000015404 | Fork-head domain-containing protein. (531 aa) |
| | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (369 aa) |
| | PRKCE | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa) |
| | PDK1 | Protein-serine/threonine kinase. (436 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (242 aa) |
| | ERLIN2 | ER lipid raft associated 2. (370 aa) |
| | WDR5 | WD repeat domain 5. (334 aa) |
| | FIS1 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (758 aa) |
| | FLCN | Folliculin. (515 aa) |
| | ACMSD | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa) |
| | FABP5 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | ENSMLEP00000017280 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (149 aa) |
| | LDLRAP1 | Low density lipoprotein receptor adaptor protein 1. (308 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1301 aa) |
| | GIP | Gastric inhibitory polypeptide. (150 aa) |
| | POR | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa) |
| | FH | Fumarate hydratase. (510 aa) |
| | LOC105539813 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (534 aa) |
| | SLC27A4 | Solute carrier family 27 member 4. (651 aa) |
| | ZBTB20 | Zinc finger and BTB domain containing 20. (741 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (249 aa) |
| | SIRT7 | Sirtuin 7. (323 aa) |
| | FOXK2 | Forkhead box K2. (401 aa) |
| | PLIN5 | Perilipin 5. (476 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) |
| | CDA | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2404 aa) |
| | ENSMLEP00000019669 | Aldo_ket_red domain-containing protein. (282 aa) |
| | SLC4A1 | Anion exchange protein. (928 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (798 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (364 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1468 aa) |
| | GIT1 | GIT ArfGAP 1. (754 aa) |
| | ENSMLEP00000020744 | Uncharacterized protein. (107 aa) |
| | GUCA1C | Guanylate cyclase activator 1C. (196 aa) |
| | LONP2 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa) |
| | BCKDK | Protein-serine/threonine kinase. (412 aa) |
| | SOD1 | Superoxide dismutase 1. (129 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (365 aa) |
| | APOB | Apolipoprotein B. (4531 aa) |
| | ABCG1 | ATP binding cassette subfamily G member 1. (686 aa) |
| | CD74 | CD74 molecule. (294 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa) |
| | CPT1A | Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (753 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | SLC2A6 | Solute carrier family 2 member 6; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (507 aa) |
| | LACC1 | Uncharacterized protein. (430 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1116 aa) |
| | GCG | Glucagon. (180 aa) |
| | LPGAT1 | Lysophosphatidylglycerol acyltransferase 1. (370 aa) |
| | MBTPS1 | Membrane bound transcription factor peptidase, site 1. (1052 aa) |
| | ARV1 | ARV1 homolog, fatty acid homeostasis modulator. (271 aa) |
| | LOC105533626 | Uncharacterized protein. (220 aa) |
| | LPCAT3 | Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa) |
| | FABP3 | Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1241 aa) |
| | JMJD8 | Jumonji domain containing 8. (236 aa) |
| | PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa) |
| | GNMT | Glycine N-methyltransferase. (295 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (806 aa) |
| | HPCA | Hippocalcin. (193 aa) |
| | ATPSCKMT | ATP synthase c subunit lysine N-methyltransferase. (233 aa) |
| | NCOR2 | Nuclear receptor corepressor 2. (2402 aa) |
| | ENSMLEP00000023867 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (139 aa) |
| | GFI1 | Growth factor independent 1 transcriptional repressor. (422 aa) |
| | SIRT5 | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (310 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (604 aa) |
| | SESN2 | Sestrin 2. (450 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | NTSR1 | Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (401 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (613 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) |
| | CCDC144NL | Uncharacterized protein. (1413 aa) |
| | GUCA2B | Guanylate cyclase activator 2B. (112 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1085 aa) |
| | ENSMLEP00000025294 | Uncharacterized protein. (109 aa) |
| | SORBS1 | Sorbin and SH3 domain containing 1. (1294 aa) |
| | ATCAY | ATCAY kinesin light chain interacting caytaxin. (377 aa) |
| | PDK4 | Protein-serine/threonine kinase. (411 aa) |
| | ENSMLEP00000025945 | Uncharacterized protein. (137 aa) |
| | ABCD2 | ATP binding cassette subfamily D member 2. (740 aa) |
| | ARPP19 | cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (116 aa) |
| | ANKRD26 | Ankyrin repeat domain 26. (1694 aa) |
| | CLN3 | Battenin. (418 aa) |
| | SDHAF3 | Succinate dehydrogenase complex assembly factor 3. (125 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (426 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (506 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | PRXL2C | Uncharacterized protein. (232 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase. (432 aa) |
| | DUSP12 | Dual specificity phosphatase 12. (340 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (586 aa) |
| | GPT | Glutamic--pyruvic transaminase. (496 aa) |
| | IGFBP4 | Insulin like growth factor binding protein 4. (194 aa) |
| | ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa) |
| | SOGA1 | Suppressor of glucose, autophagy associated 1. (1474 aa) |
| | COX11 | Cytochrome c oxidase copper chaperone COX11. (276 aa) |
| | GUCA1B | Guanylate cyclase activator 1B. (180 aa) |
| | KAT2A | Lysine acetyltransferase 2A. (755 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (231 aa) |
| | MLXIPL | MLX interacting protein like. (784 aa) |
| | PINK1 | PTEN induced kinase 1. (545 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (403 aa) |
| | RCVRN | Recoverin. (200 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (335 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (441 aa) |
| | ENSMLEP00000029949 | Uncharacterized protein. (265 aa) |
| | SELENOS | Selenoprotein S. (211 aa) |
| | SNAI1 | Snail family transcriptional repressor 1. (264 aa) |
| | HPCAL1 | Hippocalcin like 1. (193 aa) |
| | SEC14L3 | SEC14 like lipid binding 3. (400 aa) |
| | PLEK | Pleckstrin. (350 aa) |
| | PLA2G3 | Phospholipase A2 group III. (509 aa) |
| | TFF3 | Trefoil factor 3. (94 aa) |
| | ENSMLEP00000030723 | Aldo_ket_red domain-containing protein. (192 aa) |
| | GCK | Phosphotransferase. (466 aa) |
| | HNF1A | HNF1 homeobox A. (662 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1124 aa) |
| | EP300 | E1A binding protein p300. (2411 aa) |
| | FMO4 | Dimethylaniline monooxygenase [N-oxide-forming]. (558 aa) |
| | C1QTNF3 | C1q domain-containing protein. (319 aa) |
| | APP | Amyloid beta precursor protein. (772 aa) |
| | C1QTNF1 | C1q and TNF related 1. (281 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1291 aa) |
| | KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa) |
| | AVPR1B | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (424 aa) |
| | FAM3C | Family with sequence similarity 3 member C. (227 aa) |
| | AK4 | Adenylate kinase 4; Belongs to the adenylate kinase family. (171 aa) |
| | LCMT1 | Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (347 aa) |
| | PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa) |
| | SPHK2 | Sphingosine kinase 2. (663 aa) |
| | NNMT | Nicotinamide N-methyltransferase. (264 aa) |
| | PHKG2 | Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (410 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (326 aa) |
| | GPD1 | Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (543 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (270 aa) |
| | ENSMLEP00000033425 | Uncharacterized protein. (234 aa) |
| | PGAM1 | Uncharacterized protein. (205 aa) |
| | TTC39B | Tetratricopeptide repeat domain 39B. (639 aa) |
| | ENSMLEP00000033803 | DJ-1_PfpI domain-containing protein. (153 aa) |
| | C1QTNF6 | C1q and TNF related 6. (278 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (794 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (233 aa) |
| | RORC | RAR related orphan receptor C. (560 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (559 aa) |
| | ENSMLEP00000034499 | Uncharacterized protein. (244 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (745 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | SLC7A11 | Solute carrier family 7 member 11. (501 aa) |
| | SEC14L4 | SEC14 like lipid binding 4. (388 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (385 aa) |
| | PRMT3 | Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (531 aa) |
| | PDK2 | Protein-serine/threonine kinase. (407 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | SRC | Tyrosine-protein kinase. (542 aa) |
| | PANK2 | Pantothenate kinase 2. (447 aa) |
| | NUPR1 | Nuclear protein 1, transcriptional regulator. (100 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (308 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (400 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa) |
| | PRKN | Ubiquitin-like domain-containing protein. (368 aa) |
| | ANTKMT | Adenine nucleotide translocase lysine methyltransferase. (182 aa) |
| | SCAP | SREBF chaperone. (1279 aa) |
| | BMP6 | Bone morphogenetic protein 6. (346 aa) |
| | DAB2 | DAB adaptor protein 2. (770 aa) |
| | GCKR | Glucokinase regulator. (625 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (734 aa) |
| | DGAT2 | Diacylglycerol O-acyltransferase 2. (388 aa) |
| | SOX9 | SRY-box transcription factor 9. (428 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (284 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | APOC2 | Apolipoprotein C2. (72 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1304 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (517 aa) |
| | PDZD3 | PDZ domain containing 3. (505 aa) |
| | MIDN | Midnolin. (391 aa) |
| | ARNT | Aryl hydrocarbon receptor nuclear translocator. (734 aa) |
| | ENSMLEP00000039593 | ADK_lid domain-containing protein; Belongs to the adenylate kinase family. (185 aa) |
| | SLC4A4 | Anion exchange protein. (1100 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa) |
| | SEC14L5 | SEC14 like lipid binding 5. (636 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | ZBTB7A | Zinc finger and BTB domain containing 7A. (347 aa) |
| | PDK3 | Protein-serine/threonine kinase. (415 aa) |
| | SREBF2 | Sterol regulatory element binding transcription factor 2. (1138 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1147 aa) |
| | ETFBKMT | Electron transfer flavoprotein subunit beta lysine methyltransferase. (262 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (428 aa) |
| | ENSMLEP00000040511 | Uncharacterized protein. (645 aa) |
| | GUCA2A | Guanylate cyclase activator 2A. (115 aa) |
| | ARL2 | ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (182 aa) |
| | IGFBP3 | Insulin like growth factor binding protein 3. (156 aa) |
| | CES1 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (515 aa) |
