STRINGSTRING
SNRPE SNRPE HNRNPA1 HNRNPA1 SF3B3 SF3B3 GPATCH1 GPATCH1 AQR AQR PPIL1 PPIL1 ALYREF ALYREF PRPF19 PRPF19 ENSMLEP00000038335 ENSMLEP00000038335 MAGOH MAGOH DDX23 DDX23 CWC22 CWC22 LOC105554415 LOC105554415 HNRNPM HNRNPM ENSMLEP00000036212 ENSMLEP00000036212 ENSMLEP00000035896 ENSMLEP00000035896 SF3A1 SF3A1 DDX5 DDX5 ENSMLEP00000035062 ENSMLEP00000035062 ENSMLEP00000034998 ENSMLEP00000034998 HNRNPK HNRNPK C19orf54 C19orf54 MTREX MTREX DDX41 DDX41 PPIE PPIE MAGOHB MAGOHB HNRNPC HNRNPC SRSF1 SRSF1 ENSMLEP00000032493 ENSMLEP00000032493 LOC105531220 LOC105531220 HNRNPU HNRNPU LOC105554897 LOC105554897 ENSMLEP00000031093 ENSMLEP00000031093 TFIP11 TFIP11 RBM8A RBM8A PPIL3 PPIL3 PPWD1 PPWD1 SRRM1 SRRM1 SNRPA1 SNRPA1 PRPF8 PRPF8 PLRG1 PLRG1 DHX35 DHX35 ENSMLEP00000027102 ENSMLEP00000027102 SLU7 SLU7 SNRPD3 SNRPD3 LSM2 LSM2 XAB2 XAB2 ENSMLEP00000025623 ENSMLEP00000025623 LOC105546285 LOC105546285 LOC105535732 LOC105535732 BCAS2 BCAS2 SART1 SART1 ENSMLEP00000024071 ENSMLEP00000024071 LSM3 LSM3 CDC40 CDC40 CWC15 CWC15 SNRNP40 SNRNP40 ENSMLEP00000021858 ENSMLEP00000021858 BUD31 BUD31 CRNKL1 CRNKL1 LOC105550087 LOC105550087 ENSMLEP00000020013 ENSMLEP00000020013 SNRPD2 SNRPD2 ISY1 ISY1 SNRPF SNRPF LOC105534884 LOC105534884 ENSMLEP00000018153 ENSMLEP00000018153 PNN PNN EFTUD2 EFTUD2 EIF4A3 EIF4A3 ENSMLEP00000016940 ENSMLEP00000016940 ENSMLEP00000016299 ENSMLEP00000016299 ENSMLEP00000016142 ENSMLEP00000016142 SYNCRIP SYNCRIP ZCCHC8 ZCCHC8 SNRPG SNRPG ENSMLEP00000014058 ENSMLEP00000014058 LSM7 LSM7 ENSMLEP00000013226 ENSMLEP00000013226 SF3A3 SF3A3 ENSMLEP00000013046 ENSMLEP00000013046 CDC5L CDC5L PRPF4B PRPF4B SYF2 SYF2 SNRPB2 SNRPB2 ENSMLEP00000011184 ENSMLEP00000011184 DHX38 DHX38 SF3B2 SF3B2 ESS2 ESS2 RALY RALY FRG1 FRG1 SNRPD1 SNRPD1 LOC105554965 LOC105554965 SNW1 SNW1 ENSMLEP00000008607 ENSMLEP00000008607 ENSMLEP00000008162 ENSMLEP00000008162 PABPC1 PABPC1 SF3B1 SF3B1 ENSMLEP00000005622 ENSMLEP00000005622 HNRNPF HNRNPF SNRPB SNRPB RBMX RBMX PPIL2 PPIL2 SF3B6 SF3B6 ENSMLEP00000004386 ENSMLEP00000004386 SNRNP200 SNRNP200 CACTIN CACTIN ENSMLEP00000003707 ENSMLEP00000003707 LOC105535221 LOC105535221 WDR25 WDR25 HNRNPR HNRNPR LOC105542818 LOC105542818 RBM44 RBM44 ENSMLEP00000001649 ENSMLEP00000001649 DHX8 DHX8 WDR83 WDR83 LOC105528776 LOC105528776 ENSMLEP00000000335 ENSMLEP00000000335
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
HNRNPA1Heterogeneous nuclear ribonucleoprotein A1. (372 aa)
SF3B3Splicing factor 3b subunit 3. (1197 aa)
GPATCH1G-patch domain containing 1. (831 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1480 aa)
PPIL1Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
ALYREFAly/REF export factor. (207 aa)
PRPF19Pre-mRNA processing factor 19. (504 aa)
ENSMLEP00000038335Uncharacterized protein. (575 aa)
MAGOHMago homolog, exon junction complex subunit. (149 aa)
DDX23DEAD-box helicase 23. (820 aa)
CWC22CWC22 spliceosome associated protein homolog. (907 aa)
LOC105554415Uncharacterized protein. (139 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (730 aa)
ENSMLEP00000036212Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (157 aa)
ENSMLEP00000035896RRM domain-containing protein. (313 aa)
SF3A1Splicing factor 3a subunit 1. (793 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
ENSMLEP00000035062Uncharacterized protein. (187 aa)
ENSMLEP00000034998Uncharacterized protein. (437 aa)
HNRNPKHeterogeneous nuclear ribonucleoprotein K. (464 aa)
C19orf54Chromosome 19 open reading frame 54. (351 aa)
MTREXMtr4 exosome RNA helicase. (1042 aa)
DDX41DEAD-box helicase 41. (626 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (301 aa)
MAGOHBMago homolog B, exon junction complex subunit. (148 aa)
HNRNPCRRM domain-containing protein. (321 aa)
SRSF1Serine and arginine rich splicing factor 1. (248 aa)
ENSMLEP00000032493RRM domain-containing protein. (350 aa)
LOC105531220RRM domain-containing protein. (264 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (602 aa)
LOC105554897Uncharacterized protein. (305 aa)
ENSMLEP00000031093Uncharacterized protein. (136 aa)
TFIP11Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] (837 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
PPIL3Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (180 aa)
PPWD1Peptidylprolyl isomerase domain and WD repeat containing 1. (646 aa)
SRRM1PWI domain-containing protein. (898 aa)
SNRPA1Small nuclear ribonucleoprotein polypeptide A. (255 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
PLRG1Pleiotropic regulator 1. (494 aa)
DHX35DEAH-box helicase 35. (703 aa)
ENSMLEP00000027102RRM domain-containing protein. (280 aa)
SLU7SLU7 homolog, splicing factor. (586 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
XAB2XPA binding protein 2. (855 aa)
ENSMLEP00000025623Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (90 aa)
LOC105546285RRM domain-containing protein. (286 aa)
LOC105535732Matrin-type domain-containing protein. (470 aa)
BCAS2BCAS2 pre-mRNA processing factor. (225 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (729 aa)
ENSMLEP00000024071Sm domain-containing protein. (71 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
CDC40Cell division cycle 40. (579 aa)
CWC15CWC15 spliceosome associated protein homolog. (229 aa)
SNRNP40Small nuclear ribonucleoprotein U5 subunit 40. (357 aa)
ENSMLEP00000021858Uncharacterized protein; Belongs to the DEAD box helicase family. (749 aa)
BUD31BUD31 homolog. (144 aa)
CRNKL1Crooked neck pre-mRNA splicing factor 1. (842 aa)
LOC105550087Uncharacterized protein. (310 aa)
ENSMLEP00000020013annotation not available (74 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (69 aa)
ISY1Uncharacterized protein. (285 aa)
SNRPFSm domain-containing protein. (127 aa)
LOC105534884RRM domain-containing protein. (352 aa)
ENSMLEP00000018153Uncharacterized protein. (372 aa)
PNNPinin, desmosome associated protein. (717 aa)
EFTUD2Elongation factor Tu GTP binding domain containing 2. (972 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (354 aa)
ENSMLEP00000016940Uncharacterized protein. (318 aa)
ENSMLEP00000016299Uncharacterized protein. (54 aa)
ENSMLEP00000016142PWI domain-containing protein. (761 aa)
SYNCRIPSynaptotagmin binding cytoplasmic RNA interacting protein. (641 aa)
ZCCHC8Zinc finger CCHC-type containing 8. (681 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (96 aa)
ENSMLEP00000014058Sm domain-containing protein. (91 aa)
LSM7LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (103 aa)
ENSMLEP00000013226RRM domain-containing protein. (256 aa)
SF3A3Splicing factor 3a subunit 3. (501 aa)
ENSMLEP00000013046Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (74 aa)
CDC5LCell division cycle 5 like. (802 aa)
PRPF4BPre-mRNA processing factor 4B. (1007 aa)
SYF2SYF2 pre-mRNA splicing factor. (243 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (208 aa)
ENSMLEP00000011184Uncharacterized protein. (308 aa)
DHX38DEAH-box helicase 38. (1234 aa)
SF3B2Splicing factor 3b subunit 2. (895 aa)
ESS2Ess-2 splicing factor homolog. (476 aa)
RALYRALY heterogeneous nuclear ribonucleoprotein. (310 aa)
FRG1FSHD region gene 1. (258 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (130 aa)
LOC105554965Uncharacterized protein. (436 aa)
SNW1SNW domain containing 1. (571 aa)
ENSMLEP00000008607Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (70 aa)
ENSMLEP00000008162WD_REPEATS_REGION domain-containing protein. (345 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (634 aa)
SF3B1Splicing factor 3b subunit 1. (1200 aa)
ENSMLEP00000005622Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
HNRNPFHeterogeneous nuclear ribonucleoprotein F. (415 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (240 aa)
RBMXRRM domain-containing protein. (391 aa)
PPIL2Peptidylprolyl isomerase like 2. (509 aa)
SF3B6Splicing factor 3b subunit 6. (125 aa)
ENSMLEP00000004386Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (85 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa)
CACTINCactin, spliceosome C complex subunit. (741 aa)
ENSMLEP00000003707SF3A2 domain-containing protein. (182 aa)
LOC105535221Uncharacterized protein. (248 aa)
WDR25WD repeat domain 25. (544 aa)
HNRNPRHeterogeneous nuclear ribonucleoprotein R. (620 aa)
LOC105542818Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa)
RBM44RNA binding motif protein 44. (1055 aa)
ENSMLEP00000001649RRM domain-containing protein. (305 aa)
DHX8DEAH-box helicase 8. (1142 aa)
WDR83WD repeat domain 83. (315 aa)
LOC105528776RRM domain-containing protein. (180 aa)
ENSMLEP00000000335Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
Your Current Organism:
Mandrillus leucophaeus
NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill
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