41 items (Mandrillus leucophaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARHGEF2	Rho/Rac guanine nucleotide exchange factor 2. (996 aa)
	CAB39	Calcium binding protein 39. (341 aa)
	PYCARD	PYD and CARD domain containing. (195 aa)
	TSPO	Translocator protein. (169 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
	MLST8	MTOR associated protein, LST8 homolog. (335 aa)
	RPTOR	Regulatory associated protein of MTOR complex 1. (1291 aa)
	BDKRB2	Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
	AKR1B1	Aldo-keto reductase family 1 member B. (316 aa)
	AQP5	Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (262 aa)
	XRCC5	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa)
	AQP1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
	RELB	RELB proto-oncogene, NF-kB subunit. (509 aa)
	LRRC8E	Leucine rich repeat containing 8 VRAC subunit E. (796 aa)
	SLC12A6	Solute carrier family 12 member 6. (1150 aa)
	ERRFI1	ERBB receptor feedback inhibitor 1. (462 aa)
	PTGS2	Prostaglandin-endoperoxide synthase 2. (604 aa)
	DDX3X	DEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (733 aa)
	ZFP36L1	ZFP36 ring finger protein like 1. (338 aa)
	OXSR1	Oxidative stress responsive kinase 1. (580 aa)
	NFAT5	Nuclear factor of activated T cells 5. (1535 aa)
	SLC4A11	Solute carrier family 4 member 11. (921 aa)
	LRRC8C	Leucine rich repeat containing 8 VRAC subunit C. (803 aa)
	WNK3	WNK lysine deficient protein kinase 3. (1797 aa)
	SLC2A4	Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	EPO	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
	RCSD1	RCSD domain containing 1. (468 aa)
	LOC105534152	Uncharacterized protein; Belongs to the peptidase C14A family. (352 aa)
	MYLK	Myosin light chain kinase. (1912 aa)
	CAPN3	Calpain 3; Belongs to the peptidase C2 family. (821 aa)
	SLC2A1	Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (506 aa)
	STK39	Serine/threonine kinase 39. (475 aa)
	LOC105553473	Aldo_ket_red domain-containing protein. (294 aa)
	YBX3	Y-box binding protein 3. (364 aa)
	LOC105550341	Aldo_ket_red domain-containing protein. (306 aa)
	CASP1	Caspase 1; Belongs to the peptidase C14A family. (404 aa)
	TRPV4	Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
	ENSMLEP00000024588	Aldo_ket_red domain-containing protein. (279 aa)
	ENSMLEP00000024959	Pannexin_like domain-containing protein. (150 aa)
	PKD2	EF-hand domain-containing protein. (386 aa)
	SCN2A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2005 aa)

Your Current Organism:

Mandrillus leucophaeus

NCBI taxonomy Id: 9568
Other names: M. leucophaeus, Papio leucophaeus, drill

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQP1	AQP5	ENSMLEP00000034971	ENSMLEP00000034125	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.421
AQP5	AQP1	ENSMLEP00000034125	ENSMLEP00000034971	Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.421
AQP5	TRPV4	ENSMLEP00000034125	ENSMLEP00000023856	Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family.	0.504
CAB39	OXSR1	ENSMLEP00000004070	ENSMLEP00000005388	Calcium binding protein 39.	Oxidative stress responsive kinase 1.	0.548
CAB39	STK39	ENSMLEP00000004070	ENSMLEP00000018835	Calcium binding protein 39.	Serine/threonine kinase 39.	0.582
CASP1	PYCARD	ENSMLEP00000023030	ENSMLEP00000004730	Caspase 1; Belongs to the peptidase C14A family.	PYD and CARD domain containing.	0.996
ENSMLEP00000024959	LRRC8C	ENSMLEP00000024959	ENSMLEP00000009768	Pannexin_like domain-containing protein.	Leucine rich repeat containing 8 VRAC subunit C.	0.571
ENSMLEP00000024959	LRRC8E	ENSMLEP00000024959	ENSMLEP00000036819	Pannexin_like domain-containing protein.	Leucine rich repeat containing 8 VRAC subunit E.	0.559
LOC105534152	PYCARD	ENSMLEP00000014384	ENSMLEP00000004730	Uncharacterized protein; Belongs to the peptidase C14A family.	PYD and CARD domain containing.	0.973
LRRC8C	ENSMLEP00000024959	ENSMLEP00000009768	ENSMLEP00000024959	Leucine rich repeat containing 8 VRAC subunit C.	Pannexin_like domain-containing protein.	0.571
LRRC8C	LRRC8E	ENSMLEP00000009768	ENSMLEP00000036819	Leucine rich repeat containing 8 VRAC subunit C.	Leucine rich repeat containing 8 VRAC subunit E.	0.482
LRRC8E	ENSMLEP00000024959	ENSMLEP00000036819	ENSMLEP00000024959	Leucine rich repeat containing 8 VRAC subunit E.	Pannexin_like domain-containing protein.	0.559
LRRC8E	LRRC8C	ENSMLEP00000036819	ENSMLEP00000009768	Leucine rich repeat containing 8 VRAC subunit E.	Leucine rich repeat containing 8 VRAC subunit C.	0.482
MLST8	MTOR	ENSMLEP00000029859	ENSMLEP00000005374	MTOR associated protein, LST8 homolog.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.998
MLST8	RPTOR	ENSMLEP00000029859	ENSMLEP00000031715	MTOR associated protein, LST8 homolog.	Regulatory associated protein of MTOR complex 1.	0.998
MTOR	MLST8	ENSMLEP00000005374	ENSMLEP00000029859	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	MTOR associated protein, LST8 homolog.	0.998
MTOR	RPTOR	ENSMLEP00000005374	ENSMLEP00000031715	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	Regulatory associated protein of MTOR complex 1.	0.998
MTOR	XRCC5	ENSMLEP00000005374	ENSMLEP00000034176	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.877
OXSR1	CAB39	ENSMLEP00000005388	ENSMLEP00000004070	Oxidative stress responsive kinase 1.	Calcium binding protein 39.	0.548
OXSR1	WNK3	ENSMLEP00000005388	ENSMLEP00000010923	Oxidative stress responsive kinase 1.	WNK lysine deficient protein kinase 3.	0.672