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| | CSNK1A1 | Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (358 aa) |
| | LMBR1L | Limb development membrane protein 1 like; Belongs to the LIMR family. (489 aa) |
| | RBX1 | RING-type domain-containing protein. (108 aa) |
| | TLE7 | TLE family member 7. (441 aa) |
| | LRP4 | LDL receptor related protein 4. (1822 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (350 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | SOX9 | SRY-box transcription factor 9. (428 aa) |
| | GLI1 | GLI family zinc finger 1. (1106 aa) |
| | AMFR | Autocrine motility factor receptor. (558 aa) |
| | LZTS2 | Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa) |
| | DAB2 | DAB adaptor protein 2. (770 aa) |
| | DACT3 | Uncharacterized protein. (181 aa) |
| | PRKN | Ubiquitin-like domain-containing protein. (368 aa) |
| | NOTUM | Notum, palmitoleoyl-protein carboxylesterase. (338 aa) |
| | PTPRO | Protein tyrosine phosphatase receptor type O. (1216 aa) |
| | ENSMLEP00000037023 | HH_signal domain-containing protein. (126 aa) |
| | LATS2 | Non-specific serine/threonine protein kinase. (810 aa) |
| | CTNND1 | Catenin delta 1. (968 aa) |
| | DKK2 | Dickkopf WNT signaling pathway inhibitor 2. (259 aa) |
| | CSNK1A1L | Casein kinase 1 alpha 1 like. (243 aa) |
| | LATS1 | Large tumor suppressor kinase 1. (1019 aa) |
| | OTUD5 | OTU deubiquitinase 5. (434 aa) |
| | ENSMLEP00000033784 | Sox C-terminal domain-containing protein. (99 aa) |
| | APC | APC regulator of WNT signaling pathway. (2806 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (533 aa) |
| | PRICKLE1 | Prickle planar cell polarity protein 1. (831 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (753 aa) |
| | SDHAF2 | Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (154 aa) |
| | CCDC88C | Coiled-coil domain containing 88C. (2029 aa) |
| | BICC1 | BicC family RNA binding protein 1. (969 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (295 aa) |
| | SOX10 | SRY-box transcription factor 10. (420 aa) |
| | TLE5 | TLE family member 5, transcriptional modulator. (251 aa) |
| | EMD | Emerin. (328 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (260 aa) |
| | FERMT1 | Fermitin family member 1. (677 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | NPHP4 | Nephrocystin 4. (1380 aa) |
| | LOC105529488 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (458 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (473 aa) |
| | AMER1 | APC membrane recruitment protein 1. (803 aa) |
| | SOST | Sclerostin. (213 aa) |
| | NKD2 | NKD inhibitor of WNT signaling pathway 2. (407 aa) |
| | MDK | Uncharacterized protein. (161 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (555 aa) |
| | AXIN1 | Axin 1. (859 aa) |
| | PTPRU | Protein tyrosine phosphatase receptor type U. (1451 aa) |
| | NKD1 | NKD inhibitor of WNT signaling pathway 1. (501 aa) |
| | MCC | MCC regulator of WNT signaling pathway. (1014 aa) |
| | SHISA3 | Shisa family member 3. (238 aa) |
| | ENSMLEP00000017756 | Uncharacterized protein. (321 aa) |
| | LOC105545834 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (470 aa) |
| | TLE3 | TLE family member 3, transcriptional corepressor. (782 aa) |
| | AMER2 | APC membrane recruitment protein 2. (464 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (242 aa) |
| | ENSMLEP00000015812 | Uncharacterized protein. (66 aa) |
| | G3BP1 | G3BP stress granule assembly factor 1. (447 aa) |
| | LOC105532097 | Inversin. (859 aa) |
| | LOC105532200 | Uncharacterized protein. (381 aa) |
| | IGFBP1 | Insulin like growth factor binding protein 1. (260 aa) |
| | TNN | Tenascin N. (1299 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (206 aa) |
| | ENSMLEP00000015404 | Fork-head domain-containing protein. (531 aa) |
| | DKK4 | Dickkopf WNT signaling pathway inhibitor 4. (224 aa) |
| | TLE1 | TLE family member 1, transcriptional corepressor. (770 aa) |
| | JADE1 | Jade family PHD finger 1. (843 aa) |
| | DAB2IP | DAB2 interacting protein. (1153 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) |
| | CTHRC1 | Collagen triple helix repeat containing 1. (243 aa) |
| | HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1540 aa) |
| | RBMS3 | RNA binding motif single stranded interacting protein 3. (437 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (230 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (224 aa) |
| | SCYL2 | SCY1 like pseudokinase 2. (929 aa) |
| | AXIN2 | Axin 2. (843 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | GLI3 | GLI family zinc finger 3. (1580 aa) |
| | STK3 | Serine/threonine kinase 3. (519 aa) |
| | LOC105534357 | RBR-type E3 ubiquitin transferase. (77 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (221 aa) |
| | DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (266 aa) |
| | ENSMLEP00000006898 | Uncharacterized protein. (117 aa) |
| | ENSMLEP00000006851 | ANK_REP_REGION domain-containing protein. (101 aa) |
| | ISL1 | ISL LIM homeobox 1. (349 aa) |
| | FRMD8 | FERM domain containing 8. (401 aa) |
| | TBX18 | T-box transcription factor 18. (436 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (368 aa) |
| | MLLT3 | MLLT3 super elongation complex subunit. (504 aa) |
| | UBAC2 | UBA domain containing 2. (345 aa) |
| | CBY1 | Chibby family member 1, beta catenin antagonist. (126 aa) |
| | TMEM170B | Transmembrane protein 170B. (132 aa) |
| | LOC105530554 | Uncharacterized protein. (143 aa) |
| | SOX13 | SRY-box transcription factor 13. (621 aa) |
| | KREMEN1 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (465 aa) |
| | TLE2 | TLE family member 2, transcriptional corepressor. (748 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (289 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | FRZB | Frizzled related protein. (325 aa) |
| | CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa) |
| | DRAXIN | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa) |
| | CTNNBIP1 | Catenin beta interacting protein 1. (81 aa) |
| | TMEM88 | Transmembrane protein 88. (159 aa) |
| | TLE6 | TLE family member 6, subcortical maternal complex member. (496 aa) |
| | NKX2-5 | NK2 homeobox 5. (324 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (478 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (1668 aa) |
| | TLE4 | TLE family member 4, transcriptional corepressor. (765 aa) |
| | WWTR1 | WW domain containing transcription regulator 1. (390 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2581 aa) |
| | FUZ | Fuzzy planar cell polarity protein. (418 aa) |
| | ENSMLEP00000022706 | Zf-rbx1 domain-containing protein. (93 aa) |
| | LOC105543661 | Uncharacterized protein. (152 aa) |
| | ANKRD6 | Ankyrin repeat domain 6. (727 aa) |
| | PFDN5 | Uncharacterized protein. (160 aa) |
| | NOTCH1 | Notch receptor 1. (2076 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (364 aa) |
| | NPPA | Natriuretic peptide A. (153 aa) |
| | LIMD1 | LIM domains containing 1. (676 aa) |
| | ENSMLEP00000019571 | Protein kinase domain-containing protein. (324 aa) |
| | TMEM131L | Transmembrane 131 like. (1600 aa) |
